This research study discusses the flow of a magnetohydrodynamic Casson fluid under the influence of Soret, Dufour, and thermal radiation. Nonlinear partial differential equation (PDE) of governing equations is transformed into a dimensionless version of the modified PDEs presented in terms of dimensionless parameters. The solution of coupled PDEs is obtained by the finite difference method with a combination of the quasilinearization technique. The effects of various dimensionless parameters are shown graphically, such as buoyancy force (λ $\lambda $), concentration buoyancy force (
λ
C
) $({\lambda }_{{\rm{C}}})$, Casson parameter (β $\beta $), magnetic parameter (H $H$), thermal radiation (R
d $Rd$), Darcy parameter (K
0 ${K}_{0}$), Forchheimer (fr), Dufour (D
f ${D}_{f}$), Soret (Sor), Brownian motion (N
b $Nb$), thermopohersis (N
t $Nt$), and Lewis number (L
e $Le$). Prevention of heat transfer in the industrial system is critical, the velocity behavior (F $F$), thermal variation (θ $\theta $), and concentration profile (ϕ $\phi $) are more prominent in the roles of coal, gas, and solar thermal collectors.