MDCT assessment of ulcerative colitis: radiologic analysis with clinical, endoscopic, and pathologic correlation

Patel, Bijal; Mottola, Jeffrey; Sahni, V. Anik; Cantisani, Vito; Ertruk, Mehmet; Friedman, Sonia; Bellizzi, Andrew M.; Marcantonio, Andrea; Mortelé, Koenraad J.

doi:10.1007/s00261-011-9741-x

Cited by 25 publications

(32 citation statements)

References 21 publications

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“…c Axial contrast-enhanced GRE at 3T MRI demonstrates the large abscess (arrow heads) fistulized with sigmoid colon and rectum (arrows). d As with MSCT, MRI shows the nodular thickening of the left lateral wall of the rectum and the posterior wall of the bladder (arrows) austrature, and rectal luminal narrowing up to a condition of stenosis (Patel et al 2011). …”

Section: Ulcerative Colitismentioning

confidence: 97%

“…As for Crohn's disease, the symptoms of ulcerative colitis are nonspecific in nature, and consist mainly in diarrhea, tenesmus, urgency to defecation, rectal bleeding, weight loss, fever, and abdominal pain (Patel et al 2011). In this context, the diagnostic approach takes advantage by the combination of optical colonoscopy, histopathological analysis, and radiological examinations.…”

Section: Ulcerative Colitismentioning

confidence: 98%

“…MSCT allows to evaluate the intramural extension of ulcerative colitis with high accuracy and sensitivity, particularly when colonoscopy or barium enema are contraindicated (e.g., severe colitis) (Roggeveen et al 2006). Furthermore, MSCT plays a pivotal role in the detection of extraintestinal manifestations and complications, which is useful to plan therapeutic managements, as well as to assess treatment response and prognosis (Patel et al 2011;Bitterling et al 2003;Lefèvre et al 2011). Specific CT findings in the acute phase include circular and symmetric wall thickening (about 7.8 mm), ulcers, enlarged lymph nodes, mucosal hyperenhancement, reflecting a hyperemic and hypervascular conditions, and mural stratification with ''double halo'' or ''target'' sign, which can be found more frequently than in Crohn's disease (Horton et al 2000b).…”

Section: Ulcerative Colitismentioning

confidence: 99%

See 2 more Smart Citations

MSCT of the Abdomen: Colon, Rectum and CT Colonography

Neri

Mantarro

Scandiffio

et al. 2012

Multislice-Ct of the Abdomen

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Section: Ulcerative Colitismentioning

confidence: 97%

Section: Ulcerative Colitismentioning

confidence: 98%

Section: Ulcerative Colitismentioning

confidence: 99%

See 1 more Smart Citation

MSCT of the Abdomen: Colon, Rectum and CT Colonography

Neri

Mantarro

Scandiffio

et al. 2012

Multislice-Ct of the Abdomen

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“…Um estudo realizado com 23 pacientes com doença de Crohn identificou correlação positiva entre o espessamento da parede intestinal, presente na TC contrastada, e a gravidade histológica da doença. A TC convencional é limitada na sua avaliação da inflamação do intestino delgado devido a artefatos produzidos pelo colapso intestinal (PATEL et al, 2012).…”

Section: Tomografia Computadorizadaunclassified

Doença De Crohn

Papacosta¹,

Nunes²,

Pacheco³

et al. 2017

Rev Pat Tocantins

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INTRODUÇÃO: A doença de Crohn é qualificada como uma doença inflamatória intestinal, de caráter crônico, recidivante, transmural e que pode afetar qualquer parte do trato digestivo, desde a boca até o ânus, mas, principalmente, o intestino delgado e o cólon. São de cunho multifatorial, com prevalência e incidência variando de acordo com a genética, meio ambiente, microbiota intestinal e até mesmo um possível agente entérico infeccioso. É uma doença que afeta pessoas de várias idades, sexos e raças, apesar de se verificar maior incidência em jovens do sexo feminino e em regiões urbanas. METODOLOGIA: Trata-se de um artigo de revisão no qual, a partir das palavras “doença de Crohn” e “doença inflamatórias intestinais”, foi realizado busca por periódicos nos bancos de dados: PubMed, Scielo, Portal Periódicos CAPES e Google acadêmico. CONCLUSÃO: A doença de Crohn apresenta uma importante taxa de morbimortalidade no mundo, principalmente em regiões em franca urbanização e industrialização. O diagnóstico é um procedimento extremamente complicado devido a sua clínica inespecífica e pelos vários aspetos em comum com outras patologias. Dessa forma, ainda se faz necessário uma melhor investigação científica na área, com intuito de se desenvolver melhores técnicas diagnosticas e condutas a serem tomadas no seguimento e cura dessa patologia.Palavras-chave: Doença de Crohn, Doença inflamatórias intestinais, Diarreia. ABSTRACT INTRODUCTION: Crohn's disease is described as an inflammatory, chronic, recurrent, transmural inflammatory disease that can affect any part of the digestive tract, from the mouth to the anus, but especially the small intestine and colon. They are multifactorial, with prevalence and incidence varying according to genetics, environment, intestinal microbiota and even a possible infectious enteric agent. It is a disease that affects people of various ages, sexes and races, although there is a greater incidence in young women and in urban areas. METHODOLOGY: This is a review article in which, from the words "Crohn's disease" and "inflammatory bowel disease", a search was made for journals in the databases: PubMed, Scielo, Portal Periódicos CAPES and Google academic. CONCLUSION: Crohn's disease presents an important morbidity and mortality rate in the world, especially in regions where there is rapid urbanization and industrialization. Diagnosis is an extremely complicated procedure due to its nonspecific clinical and various aspects in common with other pathologies. Thus, a better scientific investigation in the area is still necessary, in order to develop better diagnostic techniques and behaviors to be taken in the follow-up and cure of this pathology. Keywords: Crohn's disease, Inflammatory bowel disease, Diarrhea.

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“…A small study by Patel et al [24] of 23 patients with UC (2012), identified positive correlation of contrast-enhanced CT features (bowel wall thickening, mucosal hyperenhancement and mural stratification), compared with clinical assessment (p < 0.05) and colonoscopy (p < 0.0001) in evaluating UC disease severity. However, only increasing bowel wall thickness on CT correlated with histological disease severity [24] . Conventional CT is limited in its assessment of small bowel inflammation due to artefact produced from collapsed bowel loops.…”

Section: Ulcerative Colitismentioning

confidence: 99%