Mean Platelet Volume in Pseudoexfoliation Syndrome and Glaucoma

Türkçü, Fatih Mehmet; Yüksel, Harun; Şahin, Alparslan; Çınar, Yasin; Yüksel, Hatice; Cingü, Kürşat; Şahin, Muhammed; Yıldırım, Adnan; Çaça, İhsan

doi:10.5301/ejo.5000340

Cited by 12 publications

(11 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The role of the MPV in differentiation between BD and recurrent oral aphthous ulcers was also investigated, but no evidence for the effectiveness of the MPV in such differentiation could be obtained 23. In a recent study, Türkçü et al examined the MPV in 36 BD patients with ocular findings and found no significant change 6. However, in a very recent study from Turkey, MPV and severity of BD were found to be correlated with each other 31.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Can we use the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values for the diagnosis of anterior uveitis in patients with Behcet’s disease?

Avcı¹,

Avci²,

Erden

et al. 2017

TCRM

View full text Add to dashboard Cite

IntroductionThe purpose of this study was to compare the value of hematological parameters, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV), as indicators of anterior uveal segment involvement in patients with Behcet’s disease (BD).Patients and methodsHospital-based records of a total of 912 patients with BD from the dermatology clinic and healthy volunteers from the checkup clinic were assessed retrospectively. After applying the exclusion criteria of the study, 71 of the BD patients with anterior uveitis, 69 of the BD patients without ophthalmological pathology and 151 healthy volunteers were included in the study. MPV, PLR, and NLR values of patients and healthy volunteers were compared.ResultsAll MPV, PLR, and NLR values of patients who had anterior uveitis were significantly higher than those of other patients and healthy volunteers. Statistically, considering area under curves (ratio): NLR was 0.725 (0.653–0.797), P<0.001; PLR was 0.600 (0.523–0.676), P=0.012, and MPV was 0.358 (0.279–0.437), P<0.001.ConclusionMPV, PLR, and NLR are all valuable for assessment of anterior uveal segment involvement in patients with BD. However, the NLR seems to be better than the PLR and MPV for indicating anterior uveitis due to BD.

show abstract

Section: Discussionmentioning

confidence: 99%

“…In the literature, a limited number of studies have attempted to identify an inflammatory marker which can predict uveitis. Türkçü et al reported that initially, mean platelet volume (MPV) was significantly lower in patients with active uveitis than in controls, but the significance disappeared over time 6,7…”

Section: Introductionmentioning

confidence: 99%

Can we use the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values for the diagnosis of anterior uveitis in patients with Behcet’s disease?

Avcı¹,

Avci²,

Erden

et al. 2017

TCRM

View full text Add to dashboard Cite

show abstract

“…Özellikle tıkayıcı vasküler hastalıklarda ortalama trombosit hacmi (OTH) değerlerinin normal popülasyona göre daha yüksek olduğu çeşitli çalışmalarda bildirilmiştir [3,4]. Daha önceki çalışmalarımızda OTH değerlerinin retinal ven tıkanıklıkları [5], psödoeksfoliasyon sendromu [6] ve aktif oküler Behçet [7] [3,11]. Pulmoner emboli hastalarında erken dönem hastane mortalitesi için bir belirteç olabileceği de öne sürülmüştür [12].…”

Section: Introductionunclassified

“…Kliniğimizde gerçekleştirdiğimiz bir çalışmada psödoeksfoliasyonlu ve psödoeksfoliatif glokomlu olgularda OTH değerlerinin kontrol grubuna göre anlamlı olarak yüksek olduğunu saptadık [6]. Bu çalışmada OTH yüksekliğinin nedeni olarak psödoeksfoliatif materyalin endotelde birikimine bağlı endotel hücre yetmezliği neticesi oluşabileceği öne sürülmüştür [17].…”

Section: Introductionunclassified

Mean platelet volume in patients with retinopathy of prematurity

Yüksel

Şahin²,

Şahin³

et al. 2014

J Clin Exp Invest

Self Cite

View full text Add to dashboard Cite

Objective: We aimed to evaluate the mean platelet volume (MPV) in patients with retinopathy of prematurity (ROP) with respect to development of type 1 ROP Methods: The medical records of the premature infants were evaluated. Babies with a birth weight under 1500 g and a gestational age under 32 weeks were enrolled to the study. Birth weight, gestational age, onset and grade of retinopathy, presence of plus disease were analyzed. At the time of type 1 ROP diagnosis, blood samples were obtained. In the patients without type 1 ROP the blood samples were also obtained at similar gestational age. Hemoglobin, hematocrit, platelet count, and MPV results were recorded. Results: Sixty-three infants were studied. 22 of them had type 1 ROP and 41 had not developed type 1 ROP. The mean gestational age and the mean birth weight between groups were not statistically significant. The mean MPV values in patients with type 1 ROP and without type 1 ROP was 9,1±2,0 fL and 9,4±1,8 fL, respectively (p=0.61). Conclusion: The results demonstrated that MPV values were not associated with severity of ROP in our study population.

show abstract

“…Empirical evidence indicates that an increased mean platelet volume (MPV) is associated with several vascular diseases [27]. Also, the increased MPV is higher in subjects with XFM relative to the healthy controls [28]. Additionally, the platelet count (PLT) and MPV have high specificity and predictive value for platelet activity.…”

Section: Introductionmentioning

confidence: 99%

Nailfold capillary morphology and platelet function in patients with exfoliative glaucoma

et al. 2019

View full text Add to dashboard Cite

Purpose The purpose of the present study was to evaluate the nailfold capillary morphological features in patients with exfoliative glaucoma (XFG) and compare them with those pertaining to primary open-angle glaucoma (POAG), normal controls and subjects with exfoliation syndrome (XFS). The second purpose was to investigate all parameters related to platelet function on the hemogram, including the platelet count (PLT), the mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT) in patients with XFG. These parameters were subsequently compared with those belonging to normal controls, POAG and XFS subjects. Methods This case control study involved 152 consecutive patients that were examined at the Glaucoma Department of Clinic for Eye Diseases, Clinical Centre of Serbia, as the referral center for glaucoma in Serbia, between June 2016 and December 2017. Results Regarding capillaroscopic characteristics, statistically significant difference was found in capillary diameter and tortuosity between the XFG and POAG group (p = 0.050 and p = 0.035) and the XFG and NC group (p = 0.003 and p = 0.044), as well as in the distribution of capillary loops and avascular zones between the XFG and NC group (p = 0.014 and p = 0.004). The subjects with XFG had lower PLT values compared to POAG patients (p = 0.022). Conclusions In conclusion, to the best of our knowledge, this study marks the first attempt to evaluate capillary morphology as well as to investigate all parameters related to platelet function on the hemogram, in patients with newly diagnosed XFG. Our findings revealed nailfold capillary morphological vascular changes in XFG patients. The subjects with XFG had lower PLT values and a higher MPV serum parameter compared to normal controls and patients with POAG. Further research in this field should therefore aim to evaluate the consequences of the aforementioned microvascular abnormalities in patients with XFG.

show abstract

Mean Platelet Volume in Pseudoexfoliation Syndrome and Glaucoma

Abstract: The MPV values in both groups with PEX were higher than those in the healthy group.

Cited by 12 publications

References 24 publications

Can we use the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values for the diagnosis of anterior uveitis in patients with Behcet’s disease?

Can we use the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values for the diagnosis of anterior uveitis in patients with Behcet’s disease?

Mean platelet volume in patients with retinopathy of prematurity

Nailfold capillary morphology and platelet function in patients with exfoliative glaucoma

Contact Info

Product

Resources

About

Mean Platelet Volume in Pseudoexfoliation Syndrome and Glaucoma

Abstract: The MPV values in both groups with PEX were higher than those in the healthy group.

Cited by 12 publications

References 24 publications

Can we use the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values for the diagnosis of anterior uveitis in patients with Behcet&rsquo;s disease?

Can we use the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values for the diagnosis of anterior uveitis in patients with Behcet&rsquo;s disease?

Mean platelet volume in patients with retinopathy of prematurity

Nailfold capillary morphology and platelet function in patients with exfoliative glaucoma

Contact Info

Product

Resources

About

Can we use the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values for the diagnosis of anterior uveitis in patients with Behcet’s disease?

Can we use the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume values for the diagnosis of anterior uveitis in patients with Behcet’s disease?