Measles: Peculiarities of the Immune Response and Therapy Possibilities at the Present Stage

Рымаренко, Н В; Krüger, Elke

doi:10.24110/0031-403x-2018-97-3-69-74

Pediatria

2018

DOI: 10.24110/0031-403x-2018-97-3-69-74

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Measles: Peculiarities of the Immune Response and Therapy Possibilities at the Present Stage

Н В Рымаренко¹,

Elke Krüger²

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2024

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The causes of TB development in a child with HIV infection

Gubkina,

Khokhlova,

Yukhimenko

et al. 2024

VIČ-infekc. immunosupr.

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The article represents a clinical observation of the development of disseminated TB in a 12-year-old child with HIV infection, a high CD4 lymphocyte count (1315 cells/μl), and undetectable viral load (<20 copies per ml of blood). Perinatal transmission occurred, HIV infection was diagnosed immediately after birth, ART was administered from the first days of life. The girl has lived in a foster family since the age of 12 months. Poor adherence to treatment resulted in raised viral load. At the same time, the girl got ill with severe measles. ART was corrected with a rapid positive immunological and virological effect. One year later, TB manifested under the guise of acute bronchopulmonary disease. The examination revealed traces of infancy intrathoracic lymph node TB in the form of small calcinates. The patient had not been previously examined for TB infection and never received preventive TB treatment. The development of acute progressive TB in the child with HIV infection and satisfactory immunological and virological indicators was caused by: lack of due interdisciplinary (pediatricians, infectiologists, phthisiologists) and interdepartmental (medical services, children’s services) interactions; poor adherence to treatment; past measles.

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The causes of TB development in a child with HIV infection

Gubkina,

Khokhlova,

Yukhimenko

et al. 2024

VIČ-infekc. immunosupr.

View full text Add to dashboard Cite

show abstract

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Measles: Peculiarities of the Immune Response and Therapy Possibilities at the Present Stage

Cited by 1 publication

References 0 publications

The causes of TB development in a child with HIV infection

The causes of TB development in a child with HIV infection

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