Measurement and control of the streamer head electric field in an atmospheric-pressure dielectric barrier plasma jet

Olszewski, Piotr; Wagenaars, E.; McKay, Kirsty; Bradley, James W.; Walsh, James L.

doi:10.1088/0963-0252/23/1/015010

Cited by 52 publications

(45 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, using spectroscopic measurements of electric field in the discharge, they report that filamentary structures create strong electric fields locally within plasma, resulting in distinctly higher electric fields in the non-uniform regime compared to that of the uniform regime [110]. This has been reported both experimentally and in simulations, for plasma jets and DBDs [111,112,113]. Due to the close relationship between electric fields and plasma chemistry, changing the mode of plasma could also influence biological effects [39,113].…”

Section: Figure A1mentioning

confidence: 93%

Nanosecond-Pulsed DBD Plasma-Generated Reactive Oxygen Species Trigger Immunogenic Cell Death in A549 Lung Carcinoma Cells through Intracellular Oxidative Stress

Lin

Truong

Patel

et al. 2017

IJMS

177

162

View full text Add to dashboard Cite

A novel application for non-thermal plasma is the induction of immunogenic cancer cell death for cancer immunotherapy. Cells undergoing immunogenic death emit danger signals which facilitate anti-tumor immune responses. Although pathways leading to immunogenic cell death are not fully understood; oxidative stress is considered to be part of the underlying mechanism. Here; we studied the interaction between dielectric barrier discharge plasma and cancer cells for oxidative stress-mediated immunogenic cell death. We assessed changes to the intracellular oxidative environment after plasma treatment and correlated it to emission of two danger signals: surface-exposed calreticulin and secreted adenosine triphosphate. Plasma-generated reactive oxygen and charged species were recognized as the major effectors of immunogenic cell death. Chemical attenuators of intracellular reactive oxygen species successfully abrogated oxidative stress following plasma treatment and modulated the emission of surface-exposed calreticulin. Secreted danger signals from cells undergoing immunogenic death enhanced the anti-tumor activity of macrophages. This study demonstrated that plasma triggers immunogenic cell death through oxidative stress pathways and highlights its potential development for cancer immunotherapy.

show abstract

Section: Figure A1mentioning

confidence: 93%

Nanosecond-Pulsed DBD Plasma-Generated Reactive Oxygen Species Trigger Immunogenic Cell Death in A549 Lung Carcinoma Cells through Intracellular Oxidative Stress

Lin

Truong

Patel

et al. 2017

IJMS

177

162

View full text Add to dashboard Cite

show abstract

“…18 This means that the observed line is not significantly broadened by the influence of the emission from the tail of the streamer, which is the case for higher electric fields in the plume, especially for the plasma jets supplied with fast rising high-voltage pulses. 40 The observed helium line is weak and visible only in the regions with significant electric field strength. 19 Electric filed along the whole capillary appears to be not so high, and consequently, the electric field behind the streamer head is lower and in this case insufficient to excite enough helium atoms to emit He 492.19 nm line in that region.…”

Section: Experimental Set-upmentioning

confidence: 97%

Electric field measurement in the dielectric tube of helium atmospheric pressure plasma jet

Sretenović

Guaitella

Sobota

et al. 2017

Journal of Applied Physics

View full text Add to dashboard Cite

The results of the electric field measurements in the capillary of the helium plasma jet are presented in this article. Distributions of the electric field for the streamers are determined for different gas flow rates. It is found that electric field strength in front of the ionization wave decreases as it approaches to the exit of the tube. The values obtained under presented experimental conditions are in the range of 5–11 kV/cm. It was found that the increase in gas flow above 1500 SCCM could induce substantial changes in the discharge operation. This is reflected through the formation of the brighter discharge region and appearance of the electric field maxima. Furthermore, using the measured values of the electric field strength in the streamer head, it was possible to estimate electron densities in the streamer channel. Maximal density of 4 × 1011 cm−3 is obtained in the vicinity of the grounded ring electrode. Similar behaviors of the electron density distributions to the distributions of the electric field strength are found under the studied experimental conditions.

show abstract

Section: Cold Atmospheric Plasma Generationmentioning

confidence: 99%

“…[67] The applied voltage influences the streamer head electric field affording a level of control over the propagation dynamics of the plasma jet. [68,69] The streamer head electric field of the plasma jet can be measured by the optical spectroscopy technique based on the polarization-dependent Stark splitting and shifting of visible helium lines. [64] For the DBD plasma jet driven by a 4.7 kV, 2.06 μs voltage pulse at a repetition rate of 7 kHz, the streamer head consisted of a strong electric field region (~24 kV/cm), which was followed by a low field region (~9 kV/cm).…”

Section: Charged Species and Electric Field Of Capmentioning

confidence: 99%

“…The streamer head electric field was influenced by the varying polarity voltage pulses to supplementary electrodes placed along the axis of the plasma jet, which also provides a new way to control the propagation dynamics of the CAP. [69] The electric charge and electric field effects discussed in this section are very important for dermatology because the energetic charged particles including electrons and ions can modify the cell membrane surface morphology, contact angle, and electric characteristics. For example, subjected to ion bombardment, the membrane surface was roughened, the contact angle of the membrane surface was varied, the membrane impedance was decreased and the conductance and capacitance were increased.…”

Section: Charged Species and Electric Field Of Capmentioning

confidence: 99%

See 1 more Smart Citation

Cold atmospheric pressure plasmas in dermatology: Sources, reactive agents, and therapeutic effects

Liu

Zhang

et al. 2020

Plasma Processes & Polymers

View full text Add to dashboard Cite

Recently, cold atmospheric pressure plasmas (CAPs) have provided many new opportunities in dermatology by providing a multimodal action of reactive agents (RA). This review critically examines the generation, transport, and physical effects induced by CAPs in dermatologic treatments. We introduce the most suitable plasma sources, which provide a multitude of physical effects on the skin without any electric or thermal shocks. The mechanisms of generation and transport of the key reactive species are introduced and examined from the viewpoint of their applications in dermatology. Special attention is paid to study the “plasmaporation” effect, which enables RA penetration through healthy and damaged skin. Plausible physical mechanisms involved in the CAP treatment of some of the most common skin diseases are analyzed.

show abstract

Measurement and control of the streamer head electric field in an atmospheric-pressure dielectric barrier plasma jet

Cited by 52 publications

References 25 publications

Nanosecond-Pulsed DBD Plasma-Generated Reactive Oxygen Species Trigger Immunogenic Cell Death in A549 Lung Carcinoma Cells through Intracellular Oxidative Stress

Nanosecond-Pulsed DBD Plasma-Generated Reactive Oxygen Species Trigger Immunogenic Cell Death in A549 Lung Carcinoma Cells through Intracellular Oxidative Stress

Electric field measurement in the dielectric tube of helium atmospheric pressure plasma jet

Cold atmospheric pressure plasmas in dermatology: Sources, reactive agents, and therapeutic effects

Contact Info

Product

Resources

About