Measurement of hematological and biochemical parameters in sheep infected with intestinal protozoa and helminthes

Abstract

Fifty blood samples were collected from sheep of different regions in Salah Al-Din Governorate for the period from November 2019 to April 2020 to detected some hematological and biochemical criteria and the infection with intestinal protozoa (Eimeria, Cryptosporidium) and helminthes (Marshallagia sp, Trichostrongylus sp, Ostertagia sp ,Haemonchus sp, Chabertia sp , Nematodirus sp , Toxocara sp, Cooperia sp , Oesophagostomum sp , Strongyloid sp) .
 The results of the study showed that the infection with intestinal protozoa and nematodes in sheep had an effect on the haematological parameters, as there was a significant decrease in the red blood cells (RBCs), volume of packed blood cells (PCV), lymphocytes compared to the control Groups reaching 4.9±1.173,21.9±7.2±1.871, 21.9± 2.881, 45.1± 3.624 respectively.
 While there was a significant increase in the number of white blood cells (WBCs) compared to the control groups reaching 13.2±3.116 respectively.
 Regarding biochemical parameters, there was a significant decrease in the concentration of protein and albumin, 5.308±0.552, 2.124±0.372 respectively, as well as a significant decrease in the concentration of iron and calcium, 158.6 ± 34.4, 8.73± 2.48 respectively, while no change in the concertation of magnesium and potassium was reported.

Analysis of gastrointestinal parasitic impact on goats: insights into infection rates, hematological and biochemical changes, and oxidative stress responses

“…The results of the current study showed a significant decrease in PCV%, Hb, and TEC; these findings are consistent with those of previous studies ( [23,3,24,27,4] . The ability of the parasitic infection to draw blood from the host as in heamonchosis and the extent of blood loss from leakage or haemorrhage resulting from severe damage caused by the heavy intestinal parasitic burden may be linked to the significantly lower concentrations of Hb, TEC and PCV in the infected animals (Urquhart et al, 1996; Aziz and Mahmoud, 2021) [45,7] . Additionally, our results indicated a considerable rise in the WBCs and absolute eosinophil count which were consistent with studies conducted by other researchers nationwide (Kumar et [24,3,2,7,5] .…”

“…The ability of the parasitic infection to draw blood from the host as in heamonchosis and the extent of blood loss from leakage or haemorrhage resulting from severe damage caused by the heavy intestinal parasitic burden may be linked to the significantly lower concentrations of Hb, TEC and PCV in the infected animals (Urquhart et al, 1996; Aziz and Mahmoud, 2021) [45,7] . Additionally, our results indicated a considerable rise in the WBCs and absolute eosinophil count which were consistent with studies conducted by other researchers nationwide (Kumar et [24,3,2,7,5] . This is because intestinal protozoa and nematodes can cause inflammation in the GI tract walls, and WBCs play a crucial part in the immunological response (Salem et al, 2017) [34] or may be the result of eosinophils increased local immunological response (Ahmed et al, 2015) [3] .…”

“…Therefore, physiological and biochemical parameters are sensitive indicators of the severity of parasite burden, and the disruption of vital metabolic activities by the liver that are necessary for the animal's optimal health and productivity. The migration of parasite larvae in hepatic and pulmonary tissues is the main source of bleeding and major tissue damage that leads to the alteration of haematological and biochemical parameters associated to GI parasites (Tariq et al, 2008; Aziz and Mahmoud, 2022) [42,7] . Stressful circumstances might increase the risk of GI parasite infections.…”

The effects of Gastro-intestinal Parasites on haemato-biochemical parameters of sheep in Kirkuk province, Iraq

“…Physiological and biochemical measures are sensitivity markers of parasite infestation severity, degree of liver damage, and liver disrupting crucial metabolic processes for the animal's normal health and maximum production. The principal cause of bleeding and significant tissue damage that results in the modification of haematological and biochemical parameters related to gastrointestinal parasites is the migration of larvae parasites in liver and pulmonary tissues (Tariq et al, 2008;Aziz and Mahmoud, 2022). Stressful situations, including weaning, food changes, bad weather, travel, and regrouping, can predispose to gastrointestinal tract (GIT) parasite infestations (Pedreira et al, 2006).…”