Measurement of in vitro cardiac deformation by means of 3D digital image correlation and ultrasound 2D speckle-tracking echocardiography

Ferraiuoli, Paolo; Fixsen, Louis S.; Kappler, Benjamin; Lopata, R.G.P.; Fenner, John; Narracott, Andrew

doi:10.1016/j.medengphy.2019.09.021

Cited by 14 publications

(9 citation statements)

References 24 publications

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“…Notably, the validation of fibre orientations in the study by Papadacci et al (2017) was performed at a depth of 15 mm, with the histological samples being 25 mm thick, that is, within the accurately estimated depth range. This means use of the method is restricted to in vitro or ex vivo experimental setups, such as those used in Ferraiuoli et al (2019) and Fixsen et al (2020), until larger-aperture matrix-array transducers with individually addressable elements are available.…”

Section: Fibre Orientationmentioning

confidence: 99%

Ultrasound-Based Estimation of Fibre-Directional Strain: A Simulation Study

Fixsen

Lopata

2022

Ultrasound in Medicine & Biology

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Section: Fibre Orientationmentioning

confidence: 99%

Ultrasound-Based Estimation of Fibre-Directional Strain: A Simulation Study

Fixsen

Lopata

2022

Ultrasound in Medicine & Biology

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“…As an example, the connective tissue fibers in the epicardium are inclined at 70° to the circumference of the heart (longitudinal direction). [ 1,2 ] As a result, the epicardium is stiffer and undergoes less deformation in the transverse direction (0.2–0.5 MPa modulus, [ 3 ] 2–6% strain [ 4 ] ) compared to the longitudinal (0.05–0.25 MPa modulus, [ 5 ] 3–10% strain [ 4 ] ). Not only is the anisotropy in these tissues directionally dependent, but the predominant orientation and composition of the biological components also varies significantly across different regions of the tissue.…”

Section: Introductionmentioning

confidence: 99%

Multiscale Anisotropic Tissue Biofabrication via Bulk Acoustic Patterning of Cells and Functional Additives in Hybrid Bioinks

Chansoria

Asif

Gupta

et al. 2022

Adv Healthcare Materials

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Recapitulation of the microstructural organization of cellular and extracellular components found in natural tissues is an important but challenging feat for tissue engineering, which demands innovation across both process and material fronts. In this work, a highly versatile ultrasound-assisted biofabrication (UAB) approach is demonstrated that utilizes radiation forces generated by superimposing ultrasonic bulk acoustic waves to rapidly organize arrays of cells and other biomaterial additives within single and multilayered hydrogel constructs. UAB is used in conjunction with a novel hybrid bioink system, comprising of cartilage-forming cells (human adipose-derived stem cells or chondrocytes) and additives to promote cell adhesion (collagen microaggregates or polycaprolactone microfibers) encapsulated within gelatin methacryloyl (GelMA) hydrogels, to fabricate cartilaginous tissue constructs featuring bulk anisotropy. The hybrid matrices fabricated under the appropriate synergistic thermo-reversible and photocrosslinking conditions demonstrate enhanced mechanical stiffness, stretchability, strength, construct shape fidelity and aligned encapsulated cell morphology and collagen II secretion in long-term culture. Hybridization of UAB is also shown with extrusion and stereolithography printing to fabricate constructs featuring 3D perfusable channels for vasculature combined with a crisscross or circumferential organization of cells and adhesive bioadditives, which is relevant for further translation of UAB toward complex physiological-scale biomimetic tissue fabrication. IntroductionCentral to the function of most tissues in the human body is the specific organization of the constitutive cells and extracellular

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“…Most manipulators known as robotic-assisted minimally invasive eye surgery, provide tilt and pan angles about the pivoting point besides one other degree of freedom along the tool axis. [13][14][15][16][17] The RCM may be achieved using various mechanisms, some of them are reported in literature. [18][19][20][21][22][23][24][25][26] Researchers mostly use these RCM mechanisms for developing robotics systems for robotic-assisted surgery and surgery training applications.…”

Section: Introductionmentioning

confidence: 99%

Robust H∞-based control of ARAS-diamond: A vitrectomy eye surgery robot

Bataleblu

Khorrambakht

Taghirad

2020

Proceedings of the Institution of Mechanical Engineers, Part C:

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In this paper, we investigate the challenges of controlling the ARAS-Diamond robot for robotic-assisted eye surgery. To eliminate the system’s inherent uncertainty effects on its performance, a cascade architecture control structure is proposed in this paper. For the inner loop of this structure, two different robust controls, namely, [Formula: see text] and μ-synthesis, with stability and performance analysis, are synthesized. The outer loop of the structure, on the other hand, controls the orientation of the surgical instrument using a well-tuned PD controller. The stability of the system as a whole, considering both inner and outer loop controllers, is analyzed in detail. Furthermore, implementation results on the real robot are presented to illustrate the effectiveness of the proposed control structure compared to that of conventional controller designs in the presence of inherent uncertainties of the system and external disturbances, and it is observed that using [Formula: see text] controller in the inner loop has superior robust performance.

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Measurement of in vitro cardiac deformation by means of 3D digital image correlation and ultrasound 2D speckle-tracking echocardiography

Cited by 14 publications

References 24 publications

Ultrasound-Based Estimation of Fibre-Directional Strain: A Simulation Study

Ultrasound-Based Estimation of Fibre-Directional Strain: A Simulation Study

Multiscale Anisotropic Tissue Biofabrication via Bulk Acoustic Patterning of Cells and Functional Additives in Hybrid Bioinks

Robust H∞-based control of ARAS-diamond: A vitrectomy eye surgery robot

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