Measurement of mechanical properties of naked cell membranes using atomic force microscope puncture test

Alkaline “Nanoswords” Coordinate Ferroptosis-like Bacterial Death for Antibiosis and Osseointegration

“…It is known that cells and bacteria are different in structure, resulting in their different sensitivity to the extracellular microenvironment, including alkalinity and Fe ions . Furthermore, cells are reported to have a lower modulus than bacteria, resulting in their low sensitivity to nanotopography. , The intrinsic differences of structure and biological functions between osteoblast and bacteria lead to their different response on MH.…”

“…For example, Fe is an essential component of several metalloproteinases, and an appropriate concentration of Fe 2+ /Fe 3+ (e.g., <12 μg/mL) plays a crucial role in the stimulation of bone regeneration; Ca 2+ increases the intracellular calcium level through Ca 2+ channels, resulting in enhanced osteoblast behaviors by upregulating the Wnt/β-catenin signaling pathway; , Si can synergistically activate MAPK and PI3K signaling pathways, directing osteoblasts migration and proliferation and accelerating bone regeneration . Furthermore, cells are reported to have a much lower modulus than bacteria, resulting in their different sensitivity to nanotopography. , …”

Mixed Silane‐based Self‐assembled Monolayers Deposited on Fluorine Doped Tin Oxide as Model System for Development of Biosensors for Toxin Detection

“…In the last couple of decades, models of the phospholipid membranes on solid surfaces have been investigated widely [11][12][13][14][15][16]. The artificial bilayer provides milieu for reconstitution of biomaterials such as proteins [17,18], DNA chains [19], pore-forming toxins [20], etc.…”

Recent Advances on the Model, Measurement Technique, and Application of Single Cell Mechanics

“…AFM can be used to measure the mechanical parameters of various biological samples, such as elasticity and adhesion [119]. So far, AFM has been applied to many kinds of cells, including epithelial cells [120][121][122], fibrocytes [123,124], cancer cells [125][126][127][128][129][130][131][132], hematopoietic stem cells [133][134][135][136], yeast cells [137], and somatic cells [138]. Bastian [139] observed the elastic behavior of epithelial cells with AFM.…”