Measurement of Red Blood Cell Zinc Concentration with Zn-Test Kit: Discrimination between Hyperthyroid Graves' Disease and Transient Thyrotoxicosis.

Abstract

Abstract.We have previously reported in patients with hyperthyroidism that the red blood cell (RBC) zinc (Zn) concentration reflects the mean thyroid hormone concentration over the preceding months. In the present study, the concentration of RBC Zn was measured by a simple and easy method with a Zntest Wako kit.Within-run and between-run precision were 1.4% and 1.3%, respectively. The relationship between RBC concentration and dilution was linear. The average recovery was 103%. A good correlation (r=0.97) was obtained between this method and atomic absorption spectrophotometry.

Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients

“…thyrotropin (TSH) receptor antibody and thyroglobulin levels, and amount of urinary iodine extraction, are regarded as useful information to discriminate GD from DT [2]. However, these tests are not necessarily available in general hospitals and clinics in Japan, and it could take several days to obtain the results.…”

“…Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients Toyoyoshi Uchida 1) , Kageumi Takeno 1) , Masahiro Goto 1) , Rei Kanno 1) , Sayaka Kubo 1) , Satomi Takahashi 1) , Kousuke Azuma 1) , Ken Sakai 1) , Yoshio Fujitani 1), 2) , Takahisa Hirose 1), 2) , Ryuzo Kawamori 1), 2), 3) and Hirotaka Watada 1) ultrasonography (EUB-525, Hitachi, Tokyo) with a 10-MHz linear transducer. Thyroid volume was calculated using the ellipsoid model ((width x length x thickness x π/3) for each lobe + (width x length x thickness) for isthmus).…”

Usefulness of the 2nd Generation Assay for Anti-TSH Receptor Antibodies to Differentiate Relapse of Graves' Thyrotoxicosis from Development of Painless Thyroiditis after Antithyroid Drug Treatment for Graves' Disease

“…Eosinophil to monocyte ratio, T3/T4 ratio and free T3/free T4 ratio are simple parameters to differentiate these two types of thyrotoxicosis [7,17,18]. Both the zinc concentration in red blood cells [19] and the third-generation assay for highly sensitive TSH measurement [20] have also been reported to be useful for differentiation. However, so far the clinical usefulness of each parameter was investigated only at the first diagnosis of thyrotoxicosis.…”

Voltammetric Determination of Trace Levels of Hg in Ayurvedic Medicine and in Cobalt-Containing Samples Using a Carbon Paste Electrode

“…Inorganic mercury undergoes methylation by microorganisms present in the environment and easily accumulates in the food chain. 3 Mercury accumulates in the human body through the food chain, resulting in nausea, vomiting, abdominal pain and ultimately kidney damage 3 in the case of an acute mercury exposure. Mercury exhibits very complex behavior in the food chain and in the human body system.…”