Measurement of the uptake of<sup>99m</sup>Tc by the thyroid

Garreta, A. C. de; Glass, H. I.; Goolden, A. W. G.

doi:10.1259/0007-1285-41-492-896

Cited by 20 publications

(8 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The small radiation dose to the thyroid and whole body (De Garreta et al 1968) and more suitable counting characteristics argue that "mTc should replace 132I for measure¬ ments in children and pregnant women. Since binding of the isotope is minimal, "mTc kinetics are not influenced by concurrent administration of the thiourylene drugs such as carbimazole.…”

Section: Discussionmentioning

confidence: 99%

A SIMPLIFIED METHOD FOR MEASURING THYROIDAL UPTAKE OF TECHNETIUM99m USING DIRECTIONAL COUNTING

Gray¹,

Hooper²,

Greig³

1973

Journal of Endocrinology

View full text Add to dashboard Cite

The uptake of technetium-99m (99mTc) by the thyroid was measured 15 min after injection using a directional counting technique. The 'washout' of thyroidal 99mTc after intravenous perchlorate injection was quantitated so that separate measurement of the extrathyroidal activity of 99mTc was unnecessary.In normal subjects the thyroidal uptake was 1\m=.\28\ m=+-\ 0\m=.\61% of the administered dose (mean \ m=+-\ 1 s.d.); in primary myxoedema 0\m=.\26\ m=+-\ 0\m=.\28%, in simple goitre 2\m=.\18\ m=+-\ 2\m=.\10%, in thyrotoxicosis 11\m=.\0 \ m=+-\ 5\m=.\4%, in hypothyroid patients with Hashimoto's disease 4\m=.\50\ m=+-\ 3\m=.\70% and in three patients with Pendred's syndrome the mean uptake was 9\m=.\3%. The technique has been evaluated and its advantages as a simple alternative to quantitative scintiscanning are discussed.

show abstract

Section: Discussionmentioning

confidence: 99%

A SIMPLIFIED METHOD FOR MEASURING THYROIDAL UPTAKE OF TECHNETIUM99m USING DIRECTIONAL COUNTING

Gray¹,

Hooper²,

Greig³

1973

Journal of Endocrinology

View full text Add to dashboard Cite

show abstract

“…Methods of measuring "sTcm uptake are based on the use of scanning equipment (Andros et al, 1965;Shimmins et al, 1968;Atkins and Richards, 1968;de Garreta et al, 1968). Such methods depend on the net difference in dot density between BRITISH MEDICAL JOURNAL 13 NOVEMBER 1971 the thyroidal and extrathyroidal regions at the time of measurement and are not based on assumptions about changes in extrathyroidal radioactivity with time.…”

Section: Discussionmentioning

confidence: 99%

Use of"Tcm for the Routine Assessment of Thyroid Function

Goolden¹,

Glass²,

Williams³

1971

BMJ

Self Cite

View full text Add to dashboard Cite

“…Patients taking cardiac glycosides were excluded. The diagnosis of thyrotoxicosis was made on clinical grounds and confirmed by two or more of the following tests: 20-minute uptake of 99mTc by the thyroid (De Garreta et al, 1968), serum proteinbound iodine, serum thyroxine, and T3-Sephadex uptake (Gimlette, 1967).…”

Section: Methodsmentioning

confidence: 99%