Measurements of Serum Calcium and Magnesium by Atomic Absorption Spectrometry

Fw, Sunderman; Je, Carroll

doi:10.1093/ajcp/43.4.302

Cited by 90 publications

(14 citation statements)

References 13 publications

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“…15 Hypomagnesemia was de¬ fined as a serum magnesium concentration of less than 1.5 mg/dL (0.62 mmol/L) on at least one of the samples,1 and hypocal¬ cemia in the present study was defined as a serum total calcium concentration of less than 8 mg/dL (2.00 mmol/L) on at least one of the samples, using the traditional defini¬ tion for full-term infants. 15 Hypomagnesemia was de¬ fined as a serum magnesium concentration of less than 1.5 mg/dL (0.62 mmol/L) on at least one of the samples,1 and hypocal¬ cemia in the present study was defined as a serum total calcium concentration of less than 8 mg/dL (2.00 mmol/L) on at least one of the samples, using the traditional defini¬ tion for full-term infants.…”

Section: Methodsmentioning

confidence: 92%

Polycythemia, Hypomagnesemia, and Hypocalcemia in Infants of Diabetic Mothers

Mimouni¹

1986

Arch Pediatr Adolesc Med

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Section: Methodsmentioning

confidence: 92%

Polycythemia, Hypomagnesemia, and Hypocalcemia in Infants of Diabetic Mothers

Mimouni¹

1986

Arch Pediatr Adolesc Med

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“…As a result of this rkers. Willis (1961) recovered investigation, we now correct all estimations of dded calcium and 100-7 % of calcium in serum to a specific gravity of 1-026. iderman Jr. and Carroll (1965) The range of values of serum calcium and magg.…”

mentioning

confidence: 99%

Estimation of calcium and magnesium in serum and urine by atomic absorption spectrophotometry

Thin

Thomson

1967

Journal of Clinical Pathology

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SYNOPSIS A method has been described for the estimation of calcium and magnesium in serum and urine using atomic absorption spectrophotometry. The precision and accuracy of the techniques have been determined and were found to be acceptable.The range of values for calcium and magnesium in the sera of normal adults was found to be: serum calcium (corrected to a specific gravity of 1 026) 8 38-10 08 mg. per 100 ml.; serum magnesium 1.83-2-43 mg. per 100 ml.A wide variety of methods has been used for the estimation of calcium and magnesium in biological fluids. Among the more recent, the technique employing the principle of atomic absorption spectroscopy appears to offer a relatively specific method, and one in which interference from other factors can be reduced to a mininum.The apparatus employed in this laboratory is a Techtron atomic absorption spectrophotometer model A.A.3, manufactured

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“…Plasma and urine Ca and Mg were measured by atomic reabsorption spectrometry [20] during acidosis caused by temporary treatment removal (3 patients) or during ammonium chloride-induced acidosis (8 patients). These 8 patients received oral ammonium chloride (100 mmol/m 2 ) at home at 12 p.m. and arrived at the hospital the next day at 8 a.m. [21].…”

Section: Methodsmentioning

confidence: 99%

Acidosis increases magnesiuria in children with distal renal tubular acidosis

2004

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In experimental animals, metabolic acidosis increases renal magnesium (Mg) excretion, whereas metabolic alkalosis reduces it. The objective of this study was to examine renal magnesium handling (U(Mg)) in children with primary distal renal tubular acidosis (DRTA). We measured U(Mg) in 11 children (3 females, 8 males, aged 6.9+/-4.9 years) with primary DRTA. They were studied either during spontaneous acidosis post treatment removal (3 patients) or after ammonium chloride (100 mmol/m2) induced acidosis (8 patients), and then following oral sodium bicarbonate load (4 g/1.73 m2). During acidosis (plasma pH 7.28+/-0.09, bicarbonate 13.2+/-4.3 mEq/l), U(Mg) was elevated (U(Mg/Cr) 0.18+/-0.06 mg/mg, normal values 0.1+/-0.06, P=0.003) although plasma Mg (P(Mg)) was in the normal range (1.93+/-0.31 mg/dl, controls 1.77+/-0.19, P=NS). After acute correction of metabolic acidosis (plasma pH 7.44+/-0.05, bicarbonate 25.6+/-1.6 mEq/l, P<0.001; urine pH 7.52+/-0.28, bicarbonate 86.9+/-39.1 mEq/l), U(Mg) decreased significantly (P=0.003), returning to control values after about 2 h (U(Mg/Cr) 0.09+/-0.06 mg/mg). Bicarbonate load resulted not only in reduction in U(Mg) but also in a decrease in urinary calcium excretion (U(Ca/Cr)) from 0.46+/-0.17 mg/mg to 0.14+/-0.12 mg/mg (P<0.001). We conclude that in children with primary DRTA, urinary Mg excretion is markedly increased and that this defect, like the hypercalciuric defect, is correctable by sodium bicarbonate administration.

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Measurements of Serum Calcium and Magnesium by Atomic Absorption Spectrometry

Cited by 90 publications

References 13 publications

Polycythemia, Hypomagnesemia, and Hypocalcemia in Infants of Diabetic Mothers

Polycythemia, Hypomagnesemia, and Hypocalcemia in Infants of Diabetic Mothers

Estimation of calcium and magnesium in serum and urine by atomic absorption spectrophotometry

Acidosis increases magnesiuria in children with distal renal tubular acidosis

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