Background We developed a radiological method, trans-lateral decubitus view, to measure stem version and assessed its reliability as well as the validity.Methods Trans-lateral decubitus view of the hip was a lateral radiograph, which was taken with the patient in lateral decubitus position, hip extension, 90° knee flexion and patella facing forward. In 40 patients, who underwent total hip replacement (THR), a trans-lateral decubitus view and CT scan of the hip were taken. Three observers measured stem neck-shaft angle (α) on hip AP view, and the stem anteversion (β), which was the angle between the axis of stem neck and axis of the femur, on the trans-lateral decubitus view. The stem version (θ) was calculated using the formula; θ = arc ((tan (180°-β) /tan (180°-α)). The intra and inter-observer reliabilities of each measurement were examined. The radiological measurements were compared with those on the CT scan to evaluate their validity.Results The mean stem anteversion on radiological measurement was 23.72° (SD 8.17) and the mean CT measurement was 23.91° (SD 10.25) (p = 0.929). The intra- and interobserver reliabilities of the radiological measurements were 0.934 and 0.931, respectively. Those of CT measurements were 0.941 and 0.942, respectively. When the radiological anteversion was between -30° and 30°, the correlation coefficient between radiological measurements and CT measurements was 0.729 (p = 0.001).Conclusion The trans-lateral decubitus method appears reliable and valid for the measurement of femoral stem version. Trial Registration: NCT02554149 (29 March 2016).