Measuring orthostatic hypotension with the Finometer device: is a blood pressure drop of one heartbeat clinically relevant?

Velde, Nathalie van der; Meiracker, Anton H. van den; Stricker, Bruno H.; Cammen, Tischa J. M. van der

doi:10.1097/mbp.0b013e3280b083bd

Cited by 60 publications

(49 citation statements)

References 37 publications

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“…[18][19][20] Custom-written MATLAB R2013 version 8.2 software was used to perform this first stage of analysis. Values extracted for analysis are defined in Table 1 and included supine values and transient stabilization parameters (Figure 1).…”

Section: Orthostatic Bp Analysismentioning

confidence: 99%

“…For example, here, we applied minimally filtered data (1-2 seconds of averaging), whereas the work reported by Romero-Ortuno 37 used a 5-second moving-average filter, which is likely to provide a lower prevalence estimate. 20 The clinical significance of this has been studied by van der Velde et al, 20 who noted that 1-and 5-second averaged signals conferred very similar odds to falls risk.…”

mentioning

confidence: 94%

“…38 A number of recent studies using beat-to-beat approaches have reported a higher prevalence of OH, which is not unexpected given the methods OH (50) OH (60) OH (70) OH (80) OH (90) OH (100) OH (110) used. One study sampled subjects attending a geriatric day center and reported a prevalence of 72% in fallers and 50% in nonfallers, 20 whereas the second reported a prevalence of 94% in community-dwelling elders. 18 Cooke et al 15 most recently reported a prevalence of 59% in community-dwelling older adults using head-up tilt testing.…”

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confidence: 99%

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Age-Related Normative Changes in Phasic Orthostatic Blood Pressure in a Large Population Study

et al. 2014

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Background-In this report, we provide the first normative reference data and prevalence estimates of impaired orthostatic blood pressure (BP) stabilization, initial orthostatic hypotension, and orthostatic hypotension based on beat-to-beat blood pressure methods in a population-representative sample. Methods and Results-Participants were recruited from a nationally representative cohort study (≥50 years). Beat-tobeat systolic BP, diastolic BP, and heart rate records were analyzed among those who underwent an active stand test (n=4475). Normograms were estimated by use of generalized additive models for location, shape, and scale with BoxCox power exponential distribution. ) of the population aged ≥50 years, with no age gradient evident. The prevalence of orthostatic hypotension was 6.9% (95% CI, 5.9%-7.8%) in the total population, increasing to 18.5% (95% CI, 9.0%-28.0%) in those aged ≥80 years old. Conclusions-Significant age-related differences exist in the time course of postural BP responses, with abnormal responses taking longer than 30 seconds to stabilize. Impaired BP stabilization is more common as we age, affecting more than two-fifths of the population aged ≥80 years, and may play a future role in the management of falls and syncope. (Circulation. 2014;130:1780-1789.)

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Section: Orthostatic Bp Analysismentioning

confidence: 99%

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confidence: 94%

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confidence: 99%

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Age-Related Normative Changes in Phasic Orthostatic Blood Pressure in a Large Population Study

et al. 2014

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“…Active stand data were exported to Microsoft Excel ® spreadsheets with the BeatScope ® 1.1a software according to the 5-second averages method [11].…”

Section: Active Stand Data Processingmentioning

confidence: 99%

Orthostatic haemodynamics may be impaired in frailty†

Romero-Ortuño¹,

Cogan²,

O’Shea³

et al. 2011

Age and Ageing

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Background: orthostatic hypotension (OH) is a physical sign that reflects a final common pathway of various forms of disordered physiology, which is the hallmark of geriatric frailty. Fried et al. recognise three increasing frailty phenotypes in older people, based on measurements of weight loss, exhaustion, grip strength, walking speed and physical activity. Orthostatic haemodynamics have not been considered as markers of frailty in older people. Objective: to classify a community sample of older people into three increasing frailty phenotypes and compare their orthostatic haemodynamics. Design: cross-sectional study. Setting: geriatric research clinic. Subjects: a total of 442 subjects (mean age 72, 72% females) without dementia or risk factors for autonomic neuropathy. Methods: the sample was classified according to modified Fried criteria. Orthostatic systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) responses were monitored during an active stand with Finometer®. Results: one hundred and ninety-eight subjects (44.8%) were classified as non-frail, 213 (48.2%) as pre-frail, and 31 (7.0%) as frail. Across groups, there was a significant increasing gradient in baseline HR (P = 0.008) and decreasing gradients in Delta HR (i.e. maximum HR within 30 s-baseline HR) (P < 0.001) and maximum HR by 30 s (P < 0.001). On average, by 30 s after stand, non-frail subjects had recovered 98% of their baseline SBP, while pre-frail and frail subjects had recovered 95 and 92%, respectively (P for trend = 0.064). Conclusions: the orthostatic HR response and, to a lesser extent, SBP recoverability, appear impaired in frailty. Orthostatic haemodynamics may be useful markers of frailty.

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“…Generally, continuous BP measurements are likely to lead to valuable new knowledge that intermittent measurements cannot detect; 31 however, presently, it is difficult to measure beat-to-beat finger BP over long periods because the pressure caused when measuring BP at the fingertip might attenuate the oxygenation of the fingertip tissue. To respond to the need for a portable device that neither restricts movement of the limbs nor causes ischemia by oppression of the cuff, we have developed this new wearable miniature cephalic laser blood flowmeter.…”

Section: Discussionmentioning

confidence: 99%

Measurement of Hemodynamics During Postural Changes Using a New Wearable Cephalic Laser Blood Flowmeter

Fujikawa

Tochikubo

Kura

et al. 2009

Circ J

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Measuring orthostatic hypotension with the Finometer device: is a blood pressure drop of one heartbeat clinically relevant?

Cited by 60 publications

References 37 publications

Age-Related Normative Changes in Phasic Orthostatic Blood Pressure in a Large Population Study

Age-Related Normative Changes in Phasic Orthostatic Blood Pressure in a Large Population Study

Orthostatic haemodynamics may be impaired in frailty†

Measurement of Hemodynamics During Postural Changes Using a New Wearable Cephalic Laser Blood Flowmeter

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