Measuring the Impact of Psychoactive Substance on Health-Related Quality of Life: An Update

González‐Sáiz, Francisco; Lozano, Óscar; Castillo, Ioseba Iraurgi

doi:10.2174/1874473710902010005

Cited by 29 publications

(16 citation statements)

References 40 publications

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“…Our results confirm that heroin users treated with methadone have significantly lower HRQoL in all domains (physical, psychological, social, environmental) of the WHOQOL and EuroQol-5D VAS than healthy controls, which was in line with previous studies 5,15. In a review by González-Saiz et al, opiate users had poorer HRQoL in most Short Form-36 dimensions (role limitation due to physical problems, bodily pain, general health, vitality, social functioning, emotional problems, and mental health) except for physical functioning, as compared with patients having minor physical problems.…”

Section: Discussionsupporting

confidence: 93%

“…Actually, HRQoL can better reflect the relationship between psychiatric symptoms and real daily life among heroin users 15. It is well recognized that heroin users have worse HRQoL than the healthy population, and in longitudinal studies, heroin users treated on a methadone maintenance treatment program have poorer HRQoL than the general population 5,15. Methadone does not “normalize” the daily lives of heroin users, and underlying problems may be neglected.…”

Section: Introductionmentioning

confidence: 99%

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Self-reported psychopathology and health-related quality of life in heroin users treated with methadone

Chen¹,

Huang²,

Shan³

et al. 2012

NDT

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BackgroundHealth-related quality of life (HRQoL) remains poor among heroin users, even after being treated with methadone. Evidence regarding self-reported psychopathology and HRQoL in heroin users is also limited. The present study aimed to investigate the association between self-reported psychopathology and HRQoL in Asian heroin users treated with methadone.MethodsThirty-nine heroin users treated with methadone and 39 healthy controls were recruited. Both groups self-reported on demographic data, the Brief Symptom Rating Scale, EuroQoL-5D, and World Health Organization Questionnaire on Quality of Life: Short Form. We compared clinical characteristics, psychopathology, and HRQoL between the two study groups. Correlation and regression analyses were conducted to explore the association between psychopathology and HRQoL in the heroin user group.ResultsHeroin users had more psychopathology and worse HRQoL than healthy controls. The HRQoL of heroin users had significant correlations with Brief Symptom Rating Scale scores. HRQoL could be predicted by depression, anxiety, paranoia, and additional symptoms (ie, poor appetite and sleep difficulties) independently.ConclusionSelf-reported psychopathology, depression, anxiety, paranoia, poor appetite, and sleep difficulties had a negative impact on each domain of HRQoL among heroin users treated with methadone. The importance of the environmental domain of HRQoL is discussed. Clinicians should recognize comorbid psychiatric symptoms early on to improve HRQoL in heroin users.

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Self-reported psychopathology and health-related quality of life in heroin users treated with methadone

Chen¹,

Huang²,

Shan³

et al. 2012

NDT

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“…Quality of life (QoL) is a subjective, person‐centered, multi‐dimensional concept that assesses physical, mental, emotional, and social well‐being. The assessment of QoL in cannabis users shows promise as one outcome measure to track alongside changes in cannabis use during treatment . Regular and heavy cannabis users have associated poorer subjective ratings on QoL with regards to exercise, activity, sleep, and general health as compared to light or non‐users .…”

Section: Introductionmentioning

confidence: 99%

Abstinence and reduced frequency of use are associated with improvements in quality of life among treatment‐seekers with cannabis use disorder

Brezing

Choi²,

Pavlicová

et al. 2018

American J Addict

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Background And Objective Many patients with cannabis use disorder (CUD) do not achieve or do not have abstinence as a goal of treatment, rather they reduce their use. Assessing outcome measures as they relate to functioning and reductions in cannabis use is an important area of study. Quality of life (QoL) shows promise as one such measure. Past studies have demonstrated gender differences in QoL and CUD. We aim to assess (1) the relationship between cannabis use and QoL and (2) gender effects in an outpatient medication treatment study for CUD. Methods Data from an 11-weeks, double-blind, placebo-controlled trial of lofexidine and dronabinol for CUD (n = 62) was analyzed. Pearson’s correlations between baseline QoL as measured with the Quality of Life, Enjoyment, and Satisfaction Questionnaire-Short Form (QLES-Q-SF) and cannabis use assessed with modified timeline follow-back (TLFB) were examined. Multiple linear regression models of cannabis use on end of study QLES-Q-SF were analyzed, while adjusting for baseline QLES-Q-SF, study arm, and gender. Moderation effects with gender were also tested. Results No significant association between baseline cannabis use and QoL was found. End of study abstinence (F1,47 = 8.34, p = .006) and reduced proportion of using days (F1,47 = 9.48, p = .004) were each significantly associated with end of study QoL. Reduction in grams (F1,27 = 0.25, p = .62) was not associated with QoL at end of study. Gender was not a significant moderator. Discussion and Conclusions Abstinence and lower frequency of use are associated with higher QoL, regardless of gender. Scientific Significance This is the first time QoL has been demonstrated to change over the course of CUD medication treatment. QoL is an important outcome in CUD treatment. Trial Registration NCT01020019. (Am J Addict 2018;27:101–107).

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“…6,7 Lower levels of social support may also predict relapse, 8 while higher social support levels are associated with reduced substance use. 9 In light of recent studies showing a relationship between quality of life and the outcome of drug dependence treatments, 10 research into this area has grown at an exponential rate. Even though only a few of these studies have focused on crack cocaine users, 11 those that do also report global impairment in quality of life in this population, with lower scores in all domains of the World Health Organization Quality of Life (WHOQOL)-bref as compared to individuals without substance use disorders.…”

Section: Introductionmentioning

confidence: 99%

Quality of life, social functioning, family structure, and treatment history associated with crack cocaine use in youth from the general population

Narvaez

Pechansky

Jansen

et al. 2015

Braz. J. Psychiatry

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Objective: To assess the relationship between crack cocaine use and dimensions of quality of life and social functioning in young adults. Methods: This was a cross-sectional, population-based study involving 1,560 participants in Pelotas, Brazil. Crack cocaine use and abuse were investigated using the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) inventory. Outcomes of interest were quality of life, religiosity, and social functioning in terms of education, occupational status, family structure, and medical treatment history. Results: Lifetime crack cocaine use was associated with poor quality of life, worse functioning, impaired academic performance, and lower religious involvement. A greater maternal presence and higher paternal absence were more also more pronounced in crack cocaine users, who were also more likely to seek psychological and psychiatric treatment than the general population. Conclusion: Quality of life was severely impacted by crack cocaine use, especially in terms of general and physical health. Social functioning also differed between the general population and crack users, who had lower educational attainment and religious involvement. Maternal presence, paternal absence, and mental health-seeking behaviors were also more frequent among crack cocaine users, although these individuals reported lower rates of treatment satisfaction. Crack cocaine users also had significant social impairment, so that interventions involving family management and a greater focus on general health, quality of life, and functioning may make crucial contributions to the recovery of this group.

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Measuring the Impact of Psychoactive Substance on Health-Related Quality of Life: An Update

Abstract: The measurement of HRQoL in the area of drug dependence is a suitable complement for finding out the deterioration caused by substance use, abuse or dependence. It is also a useful indicator for evaluating therapeutic results in this population.

Cited by 29 publications

References 40 publications

Self-reported psychopathology and health-related quality of life in heroin users treated with methadone

Self-reported psychopathology and health-related quality of life in heroin users treated with methadone

Abstinence and reduced frequency of use are associated with improvements in quality of life among treatment‐seekers with cannabis use disorder

Quality of life, social functioning, family structure, and treatment history associated with crack cocaine use in youth from the general population

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