Mechanical and Biological Characterization of Pressureless Sintered Hydroxapatite-Polyetheretherketone Biocomposite

Chang, Hengky; Bastari, Kelsen; Saraswati,; Cheang, P.

doi:10.1007/978-3-540-92841-6_63

Cited by 10 publications

(10 citation statements)

References 6 publications

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“…In-vitro bioactivity was examined by immersing the scaffolds in 5 mL of stimulated body fluid (SBF) [14] for 7 days. After which, samples were washed thrice with DI water and vacuum dried for 24 h before taking gravimetric measurements.…”

Section: In-vitro Bioactivity Of Electrospun Scaffoldsmentioning

confidence: 99%

Calcium phosphate coated Keratin–PCL scaffolds for potential bone tissue regeneration

Zhao

Lui

Choo

et al. 2015

Materials Science and Engineering: C

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Section: In-vitro Bioactivity Of Electrospun Scaffoldsmentioning

confidence: 99%

Calcium phosphate coated Keratin–PCL scaffolds for potential bone tissue regeneration

Zhao

Lui

Choo

et al. 2015

Materials Science and Engineering: C

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“…Whilst addition of bioactive materials to PEEK offers an efficient method to engineer implants with tailored biomechanical properties, it may result in reduced strength and toughness of the implant [1] . Different processing methods such as compounding and injection moulding [2][3][4] , compression moulding [5][6][7][8] , cold press sintering [9][10][11] and selective laser sintering (SLS) [12][13][14] have been used to produce bioactive PEEK/HA and β-TCP composites.…”

Section: Introductionmentioning

confidence: 99%

A novel bioactive PEEK/HA composite with controlled 3D interconnected HA network

Vaezi¹,

Yang²

2024

IJB

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Polyetheretherketone (PEEK) is a high-performance thermoplastic biomaterial which is currently used in a variety of biomedical orthopaedic applications. It has comparable tensile and compressive strength to cortical bone with favourable biocompatibility. However, natural grade PEEK-OPTIMA has shown insufficient bioactivity and limited bone integration. Bioactive PEEK composites (e.g., PEEK/calcium phosphates or Bioglass) and porous PEEK have been used to improve bone-implant interface of PEEK-based devices, but the bioactive phase distribution or porosity control is poor. In this paper, a novel method is developed to fabricate a bioactive PEEK/hydroxyapatite (PEEK/HA) composite with a unique configuration in which the HA (bioactive phase) distribution is computer-controlled within a PEEK matrix. This novel process results in complete interconnectivity of the HA network within a composite material, representing a superior advantage over alternative forms of product. The technique combines extrusion freeforming, a type of additive manufacturing (AM), and compression moulding. Compression moulding parameters, including pressure, temperature, dwelling time, and loading method together with HA microstructure were optimized by experimentation for successful biocomposite production. PEEK/HA composites with a range of HA were produced using static pressure loading to minimise air entrapment within PEEK matrix. In addition, the technique can also be employed to produce porous PEEK structures with controlled pore size and distribution.

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“…This is why considerable effort has been made to incorporate bioactive ceramics, including calcium phosphate (CaP) ceramics and bioactive glasses, as a reinforcement into PEEK implants . However, one of the problems associated with the use of brittle ceramic reinforcements is a drastic reduction in mechanical strength for large volume fractions of ceramics . In general, the mechanical properties and the biological performance of these composites are strongly affected by the amount of reinforcements as well as their properties …”

Section: Introductionmentioning

confidence: 99%

“…[13][14][15][16] However, one of the problems associated with the use of brittle ceramic reinforcements is a drastic reduction in mechanical strength for large volume fractions of ceramics. 17,18 In general, the mechanical properties and the biological performance of these composites are strongly affected by the amount of reinforcements as well as their properties. 15,19,20 In this article, we demonstrate that an alternative approach, viz., the use of ductile Ti metal as a novel reinforcement leads to improved mechanical properties while at the same time enhancing the in vitro biocompatibility of PEEK implants.…”

Section: Introductionmentioning

confidence: 99%

Reinforcement of polyetheretherketone polymer with titanium for improved mechanical properties and in vitro biocompatibility

et al. 2015

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Blends of ductile Ti metal with polyetheretherketone (PEEK) polymer were studied with regard to their mechanical properties and in vitro biocompatibility. PEEK/Ti composites with various Ti contents, ranging from 0 vol % to 60 vol %, were produced by compression molding at 370°C. In all composites produced, regardless of the initial Ti content, Ti particles were well distributed in the PEEK matrix. Addition of Ti led to a significant increase in mechanical properties of PEEK. Specifically, an increase in Ti content enhanced compressive strength and stiffness, while preserving ductile fracture behavior. In addition, the use of Ti for reinforcement of PEEK provided the composites with improved in vitro biocompatibility in terms of the attachment, proliferation, and differentiation of MC3T3-E1 cells.

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Mechanical and Biological Characterization of Pressureless Sintered Hydroxapatite-Polyetheretherketone Biocomposite

Cited by 10 publications

References 6 publications

Calcium phosphate coated Keratin–PCL scaffolds for potential bone tissue regeneration

Calcium phosphate coated Keratin–PCL scaffolds for potential bone tissue regeneration

A novel bioactive PEEK/HA composite with controlled 3D interconnected HA network

Reinforcement of polyetheretherketone polymer with titanium for improved mechanical properties and in vitro biocompatibility

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