Reinforcement of polyetheretherketone polymer with titanium for improved mechanical properties and in vitro biocompatibility

Abstract

Blends of ductile Ti metal with polyetheretherketone (PEEK) polymer were studied with regard to their mechanical properties and in vitro biocompatibility. PEEK/Ti composites with various Ti contents, ranging from 0 vol % to 60 vol %, were produced by compression molding at 370°C. In all composites produced, regardless of the initial Ti content, Ti particles were well distributed in the PEEK matrix. Addition of Ti led to a significant increase in mechanical properties of PEEK. Specifically, an increase in Ti content enhanced compressive strength and stiffness, while preserving ductile fracture behavior. In addition, the use of Ti for reinforcement of PEEK provided the composites with improved in vitro biocompatibility in terms of the attachment, proliferation, and differentiation of MC3T3-E1 cells.

Enhanced Bioactivity of Micropatterned Hydroxyapatite Embedded Poly(L-lactic) Acid for a Load-Bearing Implant

“…To evaluate the mechanical properties of pure PLLA, HA/PLLA, and patterned HA/PLLA, tension tests were conducted in accordance with ASTM 638 [ 21 , 22 ]. Specimens with a thickness of 1.5 mm and a gauge length of 8 mm were elongated uniaxially at a constant crosshead speed of 1 mm/min.…”

A Highly Hydrophilic and Biodegradable Novel Poly(amide-imide) for Biomedical Applications

“…The in vitro biocompatibility of novel PAI and pure PAI was evaluated in terms of cell adhesion and proliferation of bone mesenchymal stem cells (BMSCs). Before the experiments, the specimens were sterilized by ethylene oxide for 2 h. The BMSCs were seeded onto the specimens with densities of 5 × 10 4 cell/mL and 2 × 10 4 cell/mL for cell adhesion and proliferation, respectively [34,35]. The cells were cultured in a medium consisting of an α-MEM (Gibco) supplemented with 10% fetal bovine serum (FBS) and 1% penicillin–streptomycin in a humidified incubator with 5% CO 2 at 37 °C.…”

Strategies to improve bioactive and antibacterial properties of polyetheretherketone (PEEK) for use as orthopedic implants

“…The mechanical tests demonstrated that the compressive strength and stiffness of the composites increased with titanium content. Furthermore, the adhesion, proliferation, and differentiation of MC3T3-E1 cells on the composite material were significantly improved [ 188 ].…”

“… [ 187 ] Ti particles In vitro : increased cytocompatibility and differentiation. [ 188 ] N/A, not applicable. …”