Mechanical behaviours and mass transport properties of bone-mimicking scaffolds consisted of gyroid structures manufactured using selective laser melting

Ma, Shuai; Tang, Qian; Feng, Qiang; Song, Jun; Han, Xiaoxiao; Guo, Fuyu

doi:10.1016/j.jmbbm.2019.01.023

Cited by 175 publications

(101 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The lattice designs are carefully conceived to allow for all the qualifying attributes and to achieve the appropriate pore architecture which can enhance the artificial vascular system [20,21]. In most cases, the permeability [22,23] of a scaffold is studied in isolation without quantifying its influence on E, and due to the complex pore size. A porosity and pore size of 70-90% and 450-700 μm respectively are usually suggested as appropriate to approach the properties of human bone [12,[24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Mechanical performance of highly permeable laser melted Ti6Al4V bone scaffolds

Arjunan

Demetriou

Baroutaji

et al. 2020

Journal of the Mechanical Behavior of Biomedical Materials

125

View full text Add to dashboard Cite

Critically engineered stiffness and strength of a scaffold are crucial for managing maladapted stress concentration and reducing stress shielding. At the same time, suitable porosity and permeability are key to facilitate biological activities associated with bone growth and nutrient delivery. A systematic balance of all these parameters are required for the development of an effective bone scaffold. Traditionally, the approach has been to study each of these parameters in isolation without considering their interdependence to achieve specific properties at a certain porosity. The purpose of this study is to undertake a holistic investigation considering the stiffness, strength, permeability, and stress concentration of six scaffold architectures featuring a 68.46-90.98% porosity. With an initial target of a tibial host segment, the permeability was characterised using Computational Fluid Dynamics (CFD) in conjunction with Darcy's law. Following this, Ashby's criterion, experimental tests, and Finite Element Method (FEM) were employed to study the mechanical behaviour and their interdependencies under uniaxial compression. The FE model was validated and further extended to study the influence of stress concentration on both the stiffness and strength of the scaffolds. The results showed that the pore shape can influence permeability, stiffness, strength, and the stress concentration factor of Ti6Al4V bone scaffolds. Furthermore, the numerical results demonstrate the effect to which structural performance of highly porous scaffolds deviate, as a result of the Selective Laser Melting (SLM) process. In addition, the study demonstrates that stiffness and strength of bone scaffold at a targeted porosity is linked to the pore shape and the associated stress concentration allowing to exploit the design freedom associated with SLM.

show abstract

Section: Introductionmentioning

confidence: 99%

Mechanical performance of highly permeable laser melted Ti6Al4V bone scaffolds

Arjunan

Demetriou

Baroutaji

et al. 2020

Journal of the Mechanical Behavior of Biomedical Materials

125

View full text Add to dashboard Cite

show abstract

“…Compared to fully dense materials, porous metallic materials have many excellent properties [1], such as low density, large specific surface area, good energy absorption, and excellent permeability; therefore, they are widely used in the aerospace [2], automobile [3], architecture, medical [4][5][6][7], environmental protection [8], and acoustics [9] industries. Moreover, porous structures are ubiquitous and have been found in bones, bamboo, wood, and coral.…”

Section: Introductionmentioning

confidence: 99%

The Effects of Post Heat Treatment on the Microstructural and Mechanical Properties of an Additive-Manufactured Porous Titanium Alloy

Hua

et al. 2020

Materials

View full text Add to dashboard Cite

In this work, Ti-6Al-4V (Ti64) porous structures were prepared by selective laser melting (SLM), and the effects of post heat treatment on its microstructural and mechanical properties were investigated. The results showed that as SLM samples were mainly composed of needle-like α′ martensite. Heat treatment at 750 °C caused α′ phase to decompose, forming a lamellar α+β mixed microstructure. As the heat treatment temperature increased to 950 °C, the width of lamellar α phase gradually increased to 3.1 μm. Heat treatment also reduced the compressive strength of the samples; however, it significantly improved the ductility of the porous Ti64. Moreover, heat treatment improved the energy absorption efficiency of the porous Ti64. The samples heat-treated at 750 °C had the highest energy absorption of 233.6 ± 1.5 MJ/m3 at ε = 50%.

show abstract

“…For CIR and CU structures, the internal structure is relatively simple, so the velocity difference of the scaffold is not very large. For DIA and TC structures, due to their complex internal structure, there is also a big difference in speed [30]. DIA velocity cloud shows that the velocity on the side of the scaffold is significantly greater than the fluid flow inside the scaffold.…”

Section: Cfd Analysismentioning

confidence: 99%

3d Printed Ti6al4v Bone Scaffolds With Different Pore Structure Effects on Bone Ingrowth

Deng

Liu

et al. 2020

Preprint

View full text Add to dashboard Cite

The pore size, pore structure and porosity of porous scaffold play a vital role in bone regeneration, but its optimal shape is still unclear. In this study four kinds of porous titanium alloy scaffolds with similar porosity (65%) and pore size (650µm) and different structures were prepared by selective laser melting. Four scaffolds were implanted into the distal femur of rabbits to evaluate their bone tissue growth in vivo. Micro-CT and hard tissue sections were performed 6 and 12 weeks after the operation to reveal the bone growth of the porous scaffold. The results show that diamond lattice unit (DIA) bone growth is the best in four topological scaffolds. Through computational fluid dynamics (CFD) analysis, the permeability, velocity and flow trajectory inside the scaffold structure were calculated. The internal fluid velocity difference of the DIA structure is the smallest, and the trajectory of fluid flow inside the scaffold is the longest. It is beneficial to the growth of blood vessels and the transport of nutrients, and can promote bone formation. In this study, the mechanism of bone growth in different structures was revealed by the method of in vivo experiment combined with CFD, providing a new theoretical basis for the design of bone scaffolds in the future.

show abstract

Mechanical behaviours and mass transport properties of bone-mimicking scaffolds consisted of gyroid structures manufactured using selective laser melting

Abstract:  Gyroid scaffold has superior mechanical properties to mimic human bone;  Gyroid scaffold has adjustable permeability properties to match human bone;  SLM-produced gyroid scaffold has good consistency with its designing CAD model.

Cited by 175 publications

References 43 publications

Mechanical performance of highly permeable laser melted Ti6Al4V bone scaffolds

Mechanical performance of highly permeable laser melted Ti6Al4V bone scaffolds

The Effects of Post Heat Treatment on the Microstructural and Mechanical Properties of an Additive-Manufactured Porous Titanium Alloy

3d Printed Ti6al4v Bone Scaffolds With Different Pore Structure Effects on Bone Ingrowth

Contact Info

Product

Resources

About