Mechanical characterization of arteries affected by fetal growth restriction in guinea pigs (Cavia porcellus)

Biomechanical characterization of the passive response of the thoracic aorta in chronic hypoxic newborn lambs using an evolutionary strategy

“…Also in the Table 3 is presented the circumferential stress for three different loading conditions (pressures 60, 120 and 170 mmHg). The comparison between the CN and MN groups was made by means of circumferential stresses of the inner and outer faces ( and respectively), its difference ( ) and its average ( ) 16 , 40 . The comparison between the MN and CN groups in general do not present significant changes.…”

“…However, it is insufficient to achieve a robust mechanical characterization, since it does not allow to replicate the complex loading conditions present in a physiological state 37 , 38 . Its main result is the stress-stretch relation under uniform deformation and it provides a set of parameters that have been used to compare the mechanical responses on soft tisues 2 , 16 , 39 , 40 .…”

Study of the Effect of Treatment With Atrial Natriuretic Peptide (ANP) and Cinaciguat in Chronic Hypoxic Neonatal Lambs on Residual Strain and Microstructure of the Arteries

“…For the observation of the residual circumferential deformations of the aorta, carotid, and femoral arteries, the same rings extracted to measure thickness and diameter of the arteries are used in this assay. 2 mm long rings were extracted for each zone (Cañas et al, 2018), which are indicated in Figure 1A. Three of the samples were meant for testing and one for histology.…”

“… Wang et al (2013) by means of static and sinusoidal pressure-inflation test performed in pulmonary artery, in order to determine differences in viscoelastic behavior of chronic hypoxia-induced pulmonary hypertension and normoxic condition, concluding that static and some dynamic parameters experiment significant changes under pulmonary hypertension condition. By other side, numerical modeling is a technique widely used to describe mechanical response of arterial tissue under different conditions, where implemented models require experimental information obtained by means of the biomechanical test mentioned below ( Labrosse et al, 2009 ; García-Herrera et al, 2012 , 2016 ; Cañas et al, 2018 ). In this sense ( de Gelidi et al, 2017 ), has determined the effect of thickness and critical levels of pressure on aneurysm formation, using uniaxial tensile test and a finite element analysis of the pressurization-inflation test.…”

Biomechanical Characterization of Scallop Shells Exposed to Ocean Acidification and Warming

“…The calculation of the cross-sectional area is the same followed experimentally, described in Figure 1B . The specimen grip will act as rigid surfaces on the specimen, and the contact model used [a complete description of the contact penalty method is described by Cañas et al (2018) ] is considers that the contact pressure [ p n (MPa)] increases quadratically with the penetration [ g n (mm)] of the surfaces, i.e. : Where E n 0 (N/mm 3 ) and E n (N/mm 4 ) are constants that control the penetration.…”