“…Among different restorative solutions, implants have been successfully used to support single-tooth restorations (crowns), fixed partial dentures (bridgeworks), full arch fixed or removable dentures and restore function and aesthetics in fully and partially edentulous patients [9][10][11][12]. Worldwide statistics show that a high success rate of dental implants (over 95 %) occurs if implants are properly designed and manufactured [13], and if they are inserted in a bone segment characterized by good quality and quantity [14,15]. Nevertheless, success of the prosthetic treatment is widely affected by a number of factors that can change the biomechanical coupling between implant and bone, such as implant location, mechanical and morphological properties of bone, mechanical and geometrical features of implant as well as the prosthesis, and type and magnitude of the load transferred by the implant to the bone, as well as by host factors such as smoking and bacterial environment [16][17][18][19][20].…”