Mechanical Pleurodesis Does Not Reduce Recurrence of Spontaneous Pneumothorax: A Randomized Trial

Xiao, Min; Huang, Yuqing; Yang, Yingshun; Chen, Yingtai; Cui, Jian; Wang, Chong; Huang, Yueqin; Li, Jun; Wang, Jun

doi:10.1016/j.athoracsur.2014.06.034

Cited by 58 publications

(61 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The increasing operation duration and longer chest tube removal days in BLPA group could be an explanation of this higher financial burden. Our results together with other published studies (7,14), gave further evidence that pleura abrasion should not be routinely used in PSP patients.…”

Section: Discussionsupporting

confidence: 67%

“…Besides, adhesions formed by pleurodesis might complicate future thoracic surgery. Recently, the efficiency of pleurodesis in controlling the recurrence of PSP has been challenged by several authors (6,7). In one prospective randomized clinical trial conducted by Min and colleagues (7), 289 patients were enrolled in BLPA and bullectomy group.…”

Section: Discussionmentioning

confidence: 99%

“…Though various methods have been used in PSP treatment, including simple aspiration, chest drainage, bullectomy, medical pleurodesis, and surgical pleurodesis (2)(3)(4), bullectomy with surgical pleurodesis (abrasion, pleurectomy, surgical chemical pleurodesis, et al) under video-assisted thoracoscopy (VATS) was the most popular operative technique in PSP treatment due to its low recurrent risks (2-14%) (3,5,6). While recently a lot more evidence have shown that pleurodesis could not lower the recurrence rate of PSP (7). Besides, it might introduce the risk of bleeding and of injury to surrounding structures, which could lead to more postoperative drainage, prolonged in-hospital stay, and extra medical related cost.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pleural abrasion should not routinely preferred in treatment of primary spontaneous pneumothorax

Zhang

Feng

et al. 2017

J. Thorac. Dis.

View full text Add to dashboard Cite

Background: The aim of this study was to find out whether thoracoscopic bullectomy with pleural abrasion (BLPA) could lower the recurrence ratio in primary spontaneous pneumothorax (PSP) patients compared with bullectomy alone. (4,700.69±1,591.56 vs. 4,211.45±1,207.7, P<0.01) were observed in BLPA group. There was no significant recurrence difference between BLPA group and bullectomy group (2.6% vs. 5.3%, P=0.30).Conclusions: Compared with bullectomy, BLPA could provide similar recurrence for PSP patients, but at the price of longer operation days, longer chest tube removal days, and more medical cost, and should not be performed in PSP patients.

show abstract

Section: Discussionsupporting

confidence: 67%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Pleural abrasion should not routinely preferred in treatment of primary spontaneous pneumothorax

Zhang

Feng

et al. 2017

J. Thorac. Dis.

View full text Add to dashboard Cite

show abstract

“…Whether the pleurodesis procedure is a risk factor for the postoperative recurrence of PSP is still controversial (16,17). Apical parietal pleurectomy is another common method of mechanical pleurodesis for PSP.…”

Section: Multivariate Analysismentioning

confidence: 99%

Risk factors for recurrence of primary spontaneous pneumothorax after thoracoscopic surgery

Huang

Hua

Tian

2015

BST

View full text Add to dashboard Cite

“…4) However, as the pathogenesis associated with the formation of new growing bullae has not been elucidated, the decision to apply additional procedures, such as visceral pleural coverage, and chemical and mechanical pleurodesis, remains controversial. 3,[11][12][13] No single surgical procedure has been achieved complete satisfactory results. 4) From the results of the present study, VATS bullectomy following staple line coverage with PGA sheets may be less effective for preventing recurrence in PSP patients with apical lung blebs.…”

Section: Discussionmentioning

confidence: 99%

The Presence of a Reticulated Trabecula-Like Structure Increases the Risk for the Recurrence of Primary Spontaneous Pneumothorax after Thoracoscopic Bullectomy

Ota

Kawai

Kuriyama

2016

ATCS

View full text Add to dashboard Cite

Introduction: Deteriorated alveolar structure at the base of blebs and bullae is known as the reticulated trabecula-like structure. Its clinical significance in primary spontaneous pneumothorax (PSP) remains unclear. This study aimed to investigate the impact of the structure on recurrence of PSP after video-assisted thoracoscopic surgery (VATS) bullectomy. Methods: Between April 2010 and March 2014, 80 cases of PSP in 76 patients who underwent VATS bullectomy using endoscopic staplers were included. The staple line was covered with polyglycolic acid sheets and fibrin glue. Cases were assigned to a normal alveolar structure (NAS) group (n = 54) and a reticulated trabecula-like structure (RT) group (n = 26) based on the histological analysis. Factors associated with recurrence were analysed using logistic regression. Results: The reticulated trabecula-like structure was significantly related to apical lung blebs. The recurrence rate of PSP was significantly higher in the RT group than in the NAS group (38.5% vs. 3.7%; P <0.001). On multivariate analysis, the reticulated trabecula-like structure was an independent factor for recurrence of PSP after VATS bullectomy. Conclusion: The change of alveolar structure at the base of apical lung blebs would increase the risk for recurrence of PSP after VATS bullectomy.

show abstract

Mechanical Pleurodesis Does Not Reduce Recurrence of Spontaneous Pneumothorax: A Randomized Trial

Cited by 58 publications

References 22 publications

Pleural abrasion should not routinely preferred in treatment of primary spontaneous pneumothorax

Pleural abrasion should not routinely preferred in treatment of primary spontaneous pneumothorax

Risk factors for recurrence of primary spontaneous pneumothorax after thoracoscopic surgery

The Presence of a Reticulated Trabecula-Like Structure Increases the Risk for the Recurrence of Primary Spontaneous Pneumothorax after Thoracoscopic Bullectomy

Contact Info

Product

Resources

About