Mechanical skin thinning-to-thickening transition observed in vivo through 2D high frequency elastography

Mofid, Yassine; Josse, Gwendal; Gahagnon, Solène; Delalleau, Alexandre; Ossant, F.

doi:10.1016/j.jbiomech.2010.07.014

Cited by 7 publications

(5 citation statements)

References 32 publications

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“…As the experimental methods differ highly between studies in literature, it is not surprising that differences in outcomes occur. Mofid et al compared the mean tension on the volar forearm between participants by applying traction and found values between 1.25 and 1.44 N [29] , which is close to our own findings. Flynn uses a micro-robot that is attached to the skin with one pad and thus combines traction and compression and concluded that the reaction force of the skin at maximum displacement was around 1.6 N for both the volar forearm and the posterior upper arm [30] .…”

Section: Discussionsupporting

confidence: 91%

“…To mimic wound closure, a force of 3 N was chosen. From skin tension studies performed on intact skin, the amount of compression of the skin in response to an applied force of 3 N has been estimated to be maximally 30 mm [24] , [28] , [29] . The distance between the pads and the unloaded length of the spring have been adjusted to this.…”

Section: Methods and Proceduresmentioning

confidence: 99%

“…The stress can be applied in the form of compression, traction, suction or a combination of those options. Some of the described devices only measure the direction in which the tension is dominant [20] , [21] , while others also quantify the tension on average [22] , [23] or in a certain direction [24] – [30] . Only the devices applying traction and/or compression have shown to be capable of providing both stress level and direction.…”

Section: Introductionmentioning

confidence: 99%

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The Compressiometer: Toward a New Skin Tensiometer for Research and Surgical Planning

Scheepens

Marsidi

Genders

et al. 2022

IEEE J. Transl. Eng. Health Med.

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After surgery, around 35% of patients experience problems of excessive scarring, causing disfiguring and impaired function. An incision placed in the wrong direction causes unnecessary skin tension on the wound, resulting in increased collagen disposition and potentially hypertrophic scars. Currently, skin tension lines are used for incision planning. However, these lines are not universal and are a static representation of the skin tension that is in fact under influence of muscle action. By designing a new skin force measurement device the authors intend to make research on dynamic skin characteristics possible and to objectify incision planning and excision closure planning. The device applies a known compressive force to the skin in standardized directions and measures the displacement of the skin. This allows users to measure the skin reaction force in response to compression and to determine the optimal incision line or best wound closure direction. The device has an accuracy of 96% and a sensitivity of < 0.01 mm. It is compact, works non-invasively and standardizes measurement directions and is therefore an improvement over previously designed skin tensiometers.

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Section: Discussionsupporting

confidence: 91%

Section: Methods and Proceduresmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Compressiometer: Toward a New Skin Tensiometer for Research and Surgical Planning

Scheepens

Marsidi

Genders

et al. 2022

IEEE J. Transl. Eng. Health Med.

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“…Numerous studies on the skin have been performed to isolate the mechanical properties of the individual skin layers . Up to date, many researchers assume that the skin elasticity depends on the dermis, and most studies were focused on this layer . However, despite the small thickness of the SC compared to the whole skin (one hundredth), the SC modulus is much higher than that of dermis and is roughly 10 to 100 times higher than the entire skin modulus .…”

Section: Introductionmentioning

confidence: 99%

Raman spectroscopy: a tool for biomechanical characterization of Stratum Corneum

Vyumvuhore

Tfayli

Duplan

et al. 2013

J Raman Spectroscopy

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The mechanical properties of the Stratum Corneum (SC) have been studied by different authors at the macroscopic level, but the modification of its ultra structure during mechanical extension remains unknown. Moreover, little is described about the effect of the mechanical stress on SC barrier function. In this study, we have examined the SC structure changes, at the molecular level, during uniaxial tensile experiments. This was performed on isolated SC samples using Raman spectroscopy. We could identify the strain status of the analyzed samples by using combination of Raman spectra and Partial Least Squares processing. In addition, this approach provided information about lipids and proteins behavior during the sample extension. The structure of the intercellular lipids bilayer became less organized up to ~9% deformation. For higher strains, a plateau corresponding to the minimum organization is observed till the complete failure of the sample. In the same time, protein structures including desmosomes, were characterized by monotonic secondary structure modifications for deformations up to ~9% followed by a plateau. These observations are relevantly demonstrating the effect of extension on the skin barrier state. Such an approach could be objectively used for clinical applications to evaluate skin discomfort degree and skin elastic behavior. This could therefore help with proof of efficacy for cosmetic and dermatologic products. Copyright © 2013 John Wiley & Sons, Ltd.

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“…Quasi-static tests such as traction [4], suction [5,6] or indentation [7][8][9] have been performed in order to measure in vivo the external displacements of the skin tissue. Subsequently, Finite Element Model Updating (FEMU) was developed to determine the skin elastic behavior.…”

Section: Introductionmentioning

confidence: 99%

Measurement of the quadriceps muscle displacement and strain fields with ultrasound and Digital Image Correlation (DIC) techniques

Affagard

Feissel

Bensamoun

2015

IRBM

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Mechanical skin thinning-to-thickening transition observed in vivo through 2D high frequency elastography

Cited by 7 publications

References 32 publications

The Compressiometer: Toward a New Skin Tensiometer for Research and Surgical Planning

The Compressiometer: Toward a New Skin Tensiometer for Research and Surgical Planning

Raman spectroscopy: a tool for biomechanical characterization of Stratum Corneum

Measurement of the quadriceps muscle displacement and strain fields with ultrasound and Digital Image Correlation (DIC) techniques

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