“…BPD primarily affects infants who have required prolonged MV with positive pressure delivered via an endotracheal tube and high inspired oxygen concentrations for management [14,28,59,61,68,92,96,99]. These children have a higher incidence of lower respiratory tract infections including bronchopneumonia and/or bronchiolitis, but the majority of children improve clinically during the first one to three years of life and manifest no impairment of cardiopulmonary function or increased susceptibility to pulmonary infections by school age [14,15,28,37,40,59,60,61,109,112]. However, ehest radiographic abnormalities with interstitial Infiltrates and/or hyperexpansion [14,55,59,61,90,109,111,113] and electrocardiographic abnormalities, with right ventricular hypertrophy [55,61,90], may persist.…”