Mechanism of Action of Certain Synergists for DDT against Resistant House Flies

The inhibition of 1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane (DDT) dehydrochlorinase and gluthathione S-aryltransferase in grass-grub and housefly preparations

“…Previous attempts to find synergists for DDT have concentrated on compounds having a structural similarity to DDT (March, Metcalf & Lewallen, 1952;Speroni, 1952;Neeman, Mer, Cwilich, Modiano & Zacks, 1957;Metcalf, 1965). These compounds have been assumed to compete with DDT for the detoxication enzyme and to decrease the amount of detoxication product formed (Moorefield & Kearns, 1955). With the sensitivity of the g.l.c.…”

Insecticide Synergism, Mode of Action of Di-(p-Chlorophenyl)-(Trifluoromethyl)-Carbinol, as a Synergist to DDT Against DDT-Resistant Houseflies

“…Potatoes, however, generally were not off-flavor when lighter rates of application of chlordan were employed (4,5,7,8,10). No significant differences in flavor due to chlordan treatments were noted udth carrots (6, 7, 9, 14), snap beans (9, 11, 74), sweet potatoes (7), peas (74), tomatoes (4,6,15), cucumbers (14), or beets (6). Gould and associates (4) reported off-flavors in tomatoes, carrots, potatoes, and lima beans when chlordan sprays were employed under certain conditions.…”

“…When the reaction was carried out in presence of the carbinol, the latter was added together with the DDT, using an acetone solution of the two compounds for the deposition on the glass beads. The extraction, the correction for the presence of the carbinol, and the determination of DDT and DDE in the reaction mixture were carried out according to Moorefield and Kearns (6). The results are shown in Table VII.…”

“…Soil and foliage applications of aldrin had no 1 Present address, Wisconsin Alumni Research Foundation, Madison. Wis. effect on the flavor of potatoes (4, 7, 8, 10, 15), tomatoes (4, 6, 75), carrots (6, 7), sweet potatoes (7), and beets (6). Hening, Davis, and Robinson (6) found off-flavors in pureed squash when aldrin had been applied to the soil at the rate of 4 pounds per acre.…”

Insect Metabolism of Insecticides, The Enzymatic in vitro Degradation of DDT by Susceptible and DDT-Resistant Body Lice

“…If a particular variety of plant is preferentially attacked by insects, it may be that this variety possesses a factor which attracts the insect to the plant. Many host-plant relationships have been investigated from this point of view and, in several cases, chemicals have been isolated which function as attractants (6)(7)(8)(9)(10)(11)16,17). On the other hand, the lack of a repellan!…”