Mechanism of exercise-induced augmentation of lymphokine activated killer (LAK) cell activity in the horse

Horohov, David W.; Keadle, Tammie L.; Pourciau, Susan; Littlefield-Chabaud, Martha A.; Kamerling, S.G.; Keowen, Michael L.; French, Dennis D.; Melrose, Patricia A.

doi:10.1016/s0165-2427(96)05610-3

Cited by 27 publications

(25 citation statements)

References 16 publications

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“…Increased LAK activity immediately following peak exercise has been reported for humans [64,78,79] and horses [67]. This increase in LAK function is likely the result of a repartitioning of the cells in response to exercise and the increased cytotoxic activity of the cells in response to increased cytokine or other mediator production [80][81][82]. The overall effect we observed was intensity-dependent, as there was no effect of the initial light exercise test on either marker, similar to what occurs to LAK function following low-intensity exercise in the horse [67].…”

Section: Discussionmentioning

confidence: 90%

The Effect of Exercise and Nutritional Supplementation on Proinflammatory Cytokine Expression in Young Racehorses During Training

Horohov

Sinatra

Chopra

et al. 2012

Journal of Equine Veterinary Science

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Section: Discussionmentioning

confidence: 90%

The Effect of Exercise and Nutritional Supplementation on Proinflammatory Cytokine Expression in Young Racehorses During Training

Horohov

Sinatra

Chopra

et al. 2012

Journal of Equine Veterinary Science

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“…Numerosos estudos demonstram aumento transitório dos leucócitos após o exercício (Rose 1982, Snow et al 1983b, Iversen et al 1994, Orozco et al 2006, Orozco 2007, Ferraz et al 2009). Acredita-se que este aumento pode ser chamado de pseudoleucocitose, porque esta reação não está relacionada com a produção de novas células (resultante do aumento da secreção de adrenalina) e se deve, principalmente, pelo aumento de linfócitos em conseqüência da sua introdução em sangue periférico pelo baço e em menor escala pela medula óssea e gânglios linfáticos (Iversen et al 1994, Horohov et al 1996.…”

Section: Discussionunclassified

Perfil hematológico de equinos submetidos à prova de Team Penning

et al. 2011

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RESUMO.-As variações nos parâmetros hematológicos são utilizadas com intuito de avaliar o grau de treinamento ou estado clínico do animal. A avaliação hematológica de eqüinos em repouso tem sido objeto de estudo, a fim de estabelecer uma relação com treinamento ou capacidade atlética. Objetivou-se avaliar o perfil hematológico de eqüinos submetidos à prova de Team Penning, correlacionando o sexo e freqüência da atividade física. Mediante punção da veia jugular externa coletaram-se dois mL de sangue de 29 eqüinos, 18 machos e 11 fêmeas, em repouso (Momento I) e após o exercício (Momento II Variations in hematologic parameters are used to assess the degree of training or clinical state of the animal. The hematologic evaluation of horses at rest has been an object of study in order to establish a correlation with training or athletic capacity. The purpose of this study was to evaluate the hematologic profile of horses subjected to Team Penning competitions, correlating sex and frequency of physical activity. Two milliliters of blood were drawn through a puncture made in the external jugular vein from 29 horses, 18 males and 11 females, at rest (Moment I) and after exercising (Moment II). The blood samples were processed in an ABC VET automated veterinary hematology analyzer (Horiba ABX Diagnostics). The animals were divided into Group A, B, C and D according to the number of times they participated in the competition. The values of globular volume, hemoglobin, erythrocytes, rod-shaped segmented neutrophils and monocytes increased after the physical exercise, unlike the number of lymphocytes and eosinophils, which decreased. A comparison of the before/after exercise correlations showed no significant differences (p<0.05) between males and females. In addition, it was found that the value of the MI/MII ratio for the globular volume, hemoglobin and number of erythrocytes varied according to the frequency of the exercise. It was concluded that the Team Penning competition produces hematologic alterations in horses, which are affected by the frequency of exercising, regardless of sex.INDEX TERMS: Equus caballus, exercise, hematology.

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“…9,10 Ninety-eight days after vaccination, all ponies were challenge exposed to equine influenza virus and monitored for an additional 30 days. The third group was maintained as an unvaccinated control group.…”

mentioning

confidence: 99%

Safety, efficacy, and immunogenicity of a modified-live equine influenza virus vaccine in ponies after induction of exercise-induced immunosuppression

Lunn

Hussey²,

Sebing³

et al. 2001

javma

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Mechanism of exercise-induced augmentation of lymphokine activated killer (LAK) cell activity in the horse

Cited by 27 publications

References 16 publications

The Effect of Exercise and Nutritional Supplementation on Proinflammatory Cytokine Expression in Young Racehorses During Training

The Effect of Exercise and Nutritional Supplementation on Proinflammatory Cytokine Expression in Young Racehorses During Training

Perfil hematológico de equinos submetidos à prova de Team Penning

Safety, efficacy, and immunogenicity of a modified-live equine influenza virus vaccine in ponies after induction of exercise-induced immunosuppression

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