1997
DOI: 10.1136/bjo.81.1.85
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Mechanism of fluid transport across corneal endothelium and other epithelial layers: a possible explanation based on cyclic cell volume regulatory changes

Abstract: Maintenance of normal corneal transparency and the possible loss of it in disease continue to be relevant clinical issues. The possibility of control of corneal hydration (hence transparency) by the active intervention of the corneal limiting layers was raised for the first time by Davson in an article in the BJO in 1949.

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Cited by 39 publications
(15 citation statements)
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“…Together with fluxes of other ions, e.g. HCO3 − , the net transport generates osmotic gradients that drive water transport, with Cl − secretion providing a primary driving force for water transport across the corneal epithelium (Fischbarg, 1997). …”
Section: Electric Fields In the Corneamentioning
confidence: 99%
“…Together with fluxes of other ions, e.g. HCO3 − , the net transport generates osmotic gradients that drive water transport, with Cl − secretion providing a primary driving force for water transport across the corneal epithelium (Fischbarg, 1997). …”
Section: Electric Fields In the Corneamentioning
confidence: 99%
“…Interestingly, in the realm of electro-osmotic coupling, water secretion can also assume the paracellular pathway 5, 2831. As we strive to further delineate the nature of the solute-solvent coupling, it appears that mechanisms of cell volume regulation in response to acute osmotic shocks are invaluable 32. This is because cell volume changes, which can be measured in realtime,710, 33 are also brought about by ion transport mechanisms that are implicated in fluid transport (Fig.…”
Section: Fluid Transport By the Corneal Endotheliummentioning
confidence: 99%
“…Voriconazole is highly effective against Candida, Aspergillus, Fusarium, Paecilomyces and Scedosporium species with a MIC 90 of 0.015, 1, 2, 0.5 and 0.25 µg/ml, respectively [19][20][21][22]. It is a synthetic derivative of fluco nazole.…”
Section: Introduction To Voriconazolementioning
confidence: 99%