Mechanisms of Action of Herbal Cholagogues

Spiridonov, Nikolay A.

doi:10.4172/2167-0412.1000107

Cited by 4 publications

(2 citation statements)

References 37 publications

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“…Herbal cholagogues target different components of the complex bile production and secretion system, and exert their action via diverse routes, such as cholecystokinin-dependent and independent gallbladder contraction, up-regulation of the bile acid synthesis, stimulation of the bile salt export pump, multidrug resistance protein transporter system, and osmotic bile flow. 17 Since 2017, we have been trying one established regimen named as "Srivastava regimen for biliary sludge" which contains oral ampicillin, UDCA and Phaltrikadi Kvatha (decoction) or Ghanbati (Tablet) for minimum of 45 days, dietary fat restriction, plenty of water intake and avoiding all the possible confounding factors of gallstone diseases. 7 The results have been very promising and acceptable.…”

Section: Discussionmentioning

confidence: 99%

https://medcraveonline.com/GHOA/efficacy-of-omlivtm-an-indigenous-polyherbal-formulation-in-the-management-of-gallbladderbiliary-sludge-diseases.html

Srivastava¹

2021

GHOA

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Biliary sludge is thick concretions or precipitates like substance present in gallbladder and is considered as precursor of the gallstones. In recent era, cases have been increasing significantly because of the routine ultrasonography examination of the abdomen in any abdominal problem. Therefore, asymptomatic incidental capture of the sludge in gallbladder is common now. Most patients undergo operations due to fear of biliary complications. Omliv TM , one tablet twice daily for 45 days has been tried in these patients with acceptable results. Gallbladder sludge has been washed out by this regime. Even nonmeasurable small concretions were also washed off. I present case series of three cases of different age groups to establish the possibility of the conservative management with Omliv TM in gallbladder/biliary sludge cases. The main objective of the present case report is the successful implication of the nonsurgical conservative approach to this subset of patients in whom the Omliv TM tablet has not only proved as economic mode of treatment but can avoid surgery also.

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Section: Discussionmentioning

confidence: 99%

https://medcraveonline.com/GHOA/efficacy-of-omlivtm-an-indigenous-polyherbal-formulation-in-the-management-of-gallbladderbiliary-sludge-diseases.html

Srivastava¹

2021

GHOA

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“…Medicinal plants having hepatobiliary effect are important therapeutic agents for cholestasis. These are called as choleretics (increasing bile production) and cholagogues (promoting the flow of bile from the liver and gall bladder into the intestines) [7] .…”

Section: Introductionmentioning

confidence: 99%

Choleretic and cholagogic effects of anti-cholelithiatic plants

Ahmed¹,

Zaheer²,

Mallick³

et al. 2021

J Pharmacogn Phytochem

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A large number of people suffer from gall stone worldwide and this problem is now being increased significantly due to the malnutrition, changes in living style, lack of exercise and conditions i.e. industrialization. Medicinal plants are used from centuries due to their cultural acceptability, efficacy, safety and fewer side effects as compared to modern synthetic medicines. The aim of this review is to gather the information of the plants utilized in various parts and societies of the world against gallstones. The information provided is not only useful for common people but also for the scientific community for further phytochemical, toxicological and pharmacological studies which may lead to discovery of new, more effective and safer medicines for gallstones.

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Chemical and herbal treatment for gallstone treatment

Tendulkar,

Tendulkar

2024

Gallstone Formation, Diagnosis, Treatment and Prevention

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Mechanisms of Action of Herbal Cholagogues

Cited by 4 publications

References 37 publications

https://medcraveonline.com/GHOA/efficacy-of-omlivtm-an-indigenous-polyherbal-formulation-in-the-management-of-gallbladderbiliary-sludge-diseases.html

https://medcraveonline.com/GHOA/efficacy-of-omlivtm-an-indigenous-polyherbal-formulation-in-the-management-of-gallbladderbiliary-sludge-diseases.html

Choleretic and cholagogic effects of anti-cholelithiatic plants

Chemical and herbal treatment for gallstone treatment

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