Mechanochemical synthesis and antibacterial effect of CuBi₂O₄ nanoparticles against P. aeruginosa and S. aureus

Abstract

Nanoparticles (NPs) of CuBi2O4 with an average size around 25 nm were obtained by a novel and eco-friendly synthesis method. X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HR-TEM) reveal that CuBi2O4 NPs possess a tetragonal crystal structure. These NPs were characterised by Raman scattering, ultraviolet-visible (UV-Vis) absorption, photoluminescence (PL), and electron paramagnetic resonance (EPR) spectroscopies. Furthermore, an in vitro study of the antibacterial effect of CuBi2O4 NPs against two bacterial strains, Pseudomonas aeruginosa (ATCC 43636) and Staphylococcus aureus (ATCC 25923), was carried out. The results obtained from the counting of colony-forming units (CFUs) and by the XTT-PMS cell viability assay showed an inhibition of the bacterial growth by 88%–87% for P. aeruginosa and 100% for S. aureus, at 50 mg ml−1 of NPs concentration. The results of this work suggest that these nanoparticles have the potential to be used as antibacterial agents by embedding them into different surfaces or being dispersed in a coating, to prevent the bacterial colonisation.

Membraneless, self-powered immunosensing of a cardiac biomarker by exploiting a PEC platform based on CaBi2Ta2O9 combined with bismuth oxyiodides

“…S2. † The sample exhibited the XRD peaks of tetragonal CuBi 2 O 4 (ICSD, 67 018), SnO 2 (ICSD, 16 635) from the FTO substrate, [38][39][40] and some minor peaks attributed to Bi 2 O 3 . Fig.…”

Deposition and Characterization of Innovative Bulk Heterojunction Films Based on CuBi2O4 Nanoparticles and Poly(3,4 ethylene dioxythiophene):Poly(4-styrene sulfonate) Matrix

“…2a). All peaks in the pattern correspond to the single crystalline phase [13,15,16], and there are no other diffraction peaks attributed to impurities. An average crystallite size of 24 ± 2 nm was estimated using Scherrer's equation on the (200), (211) and (202) diffraction peaks.…”

“…The structure of CuBi 2 O 4 , space group P4/ncc and tetragonal symmetry was discovered by Boivin et al in 2001 [6]. CuBi 2 O 4 nanoparticles (NPs) have been obtained by different methodologies such as solid-state reaction [7][8][9], the hydrothermal method [10], the sonochemical approach [11] and the sol-gel method [12], as well as an innovative and environmentally friendly one-step synthesis method [13]. Until now, the main applications of this oxide are in photocatalysis, generation of hydrogen from H 2 O, degradation of water contaminants such as dyes and as microbicides [5,[13][14][15][16].…”

“…CuBi 2 O 4 nanoparticles (NPs) have been obtained by different methodologies such as solid-state reaction [7][8][9], the hydrothermal method [10], the sonochemical approach [11] and the sol-gel method [12], as well as an innovative and environmentally friendly one-step synthesis method [13]. Until now, the main applications of this oxide are in photocatalysis, generation of hydrogen from H 2 O, degradation of water contaminants such as dyes and as microbicides [5,[13][14][15][16]. Moreover, under AM1.5 and EQE (external quantum efficiency) equal to 1, the maximum theorical Jsc is 29 mA/cm 2 , which potentiates its use for solar cell applications [17].…”