Mechanosensation: Alpha-7 nAChR transduces sound signals in earless C. elegans

CHRFAM7A diversifies human immune adaption through Ca2+ signalling and actin cytoskeleton reorganization

“…These cellular responses imply that CHRFAM7A enables cellular adaptation to the mechanical properties of the tissue environment through modulation of Ca 2+ dynamics (soft) 64 , 65 and through PM localized α7/CHRFAM7A nAChR (stiff). 62 , 63 During evolution, tissue and organ specialization lead to diversity in tissue mechanics which is affected by pathological processes ( Fig. 4 a).…”