Meconium-stained amniotic fluid

Wood, Carol L.

doi:10.1016/0091-2182(94)90068-x

Cited by 6 publications

(2 citation statements)

References 28 publications

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“…Although 69 % of newborns pass meconium by 12 hours of age, many infants pass meconium prior to birth as well 1 . Various studies have reported an incidence of meconium stained amniotic fluid ranging from 1.5 to 18 % 2 .It has been suggested that the fetus passes meconium in response to hypoxia and that meconium therefore signals fetal compromise.…”

Section: Introductionmentioning

confidence: 99%

The Significance of Meconium Stained Amniotic Fluid – A Cross Sectional Study in a Rural Setup

Tayade¹

2013

Int J of Biomed & Adv Res

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Background: The significance of meconium in amniotic fluid is a widely debated subject. Traditionally meconium has been viewed as a harbinger of impending or ongoing fetal compromise; however some investigators believe that it is not associated with fetal hypoxia, acidosis or fetal distress. Others have found lower Apgar scores in meconium stained neonates. Objectives: To study the correlation of meconium in amniotic fluid with perinatal outcome. Methods: 120 consecutive, term, labouring women with meconium stained amniotic fluid on spontaneous/artificial rupture of membranes were monitored during labour with fetal heart rate abnormalities, one and five minute apgar score , umbilical cord pH at birth and neonatal complications, as outcome variables. Results:. Fetal heart rate variations were more often in cases with thick meconium (86.36%) than with thin meconium (9.75%%) (p value < 0.005). Thick meconium group neonates had lower Apgar scores as compared to moderate and thin meconium group. The umbilical cord blood pH was below 7.2 in 4(11.4%) neonates of thin meconium, 15(42.85%) in moderate meconium g and 30(68.18%) in thick meconium group (P value below 0.001). Neonatal complications were found in 36.36% of thick meconium group as compared to 14.28% of moderate meconium and none in thin meconium. Conclusions: Thick meconium should suggest immediate intervention, need for skilled paediatrician at the time of delivery and intensive care in the neonatal period to give a positive outcome

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Section: Introductionmentioning

confidence: 99%

The Significance of Meconium Stained Amniotic Fluid – A Cross Sectional Study in a Rural Setup

Tayade¹

2013

Int J of Biomed & Adv Res

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“…20 Although 70% of newborns pass meconium by 12 hours of age, many infants pass meconium prior to birth as well. 21 It has been suggested that the fetus passes meconium in response to hypoxia signaling fetal compromise. Alternatively, in utero passage of meconium may represent normal gastrointestinal tract maturation under neuronal control.…”

Section: Original Articlementioning

confidence: 99%

Prediction of Perinatal Outcome with Meconium-stained Liquor

Khatun

Parvin

Naurin

2020

Ibrahim card. med. j.

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Background & objective: Passage of meconium in the amniotic fluid during labor has long been considered as fetal compromise resulting from fetal hypoxia or increased vagal activity from cord compression. It is also a sign of normal gastrointestinal tract maturation under neuronal control. However, presence of meconium in the amniotic fluid is traditionally viewed as unfavorable perinatal outcome. So, the present study was contemplated to find the association between grade of meconium during labor and perinatal outcome. Methods: The present prospective study was conducted in the North Bengal Medical College, Sirajganj between January 2016 – April 2017. Based on predefined criteria, 53 singleton pregnant women with meconium-stained liquor (MSL) on spontaneous or artificial rupture of membrane after 37 completed weeks of gestation were included in the study. Meconium-stained liquor was graded as “Thick” if the fluid was dark green in colour, viscous, tenacious, opalescent or opaque containing large amount of particulate materials and “Thin” if the fluid was translucent, light yellow green in colour without particulate material. The perinatal outcome was evaluated in terms of APGAR score of neonates at 1 and at 5 minutes of birth, NICU admission, resuscitation needed, jaundice and respiratory distress syndrome (RDS) due to meconium aspiration. Asphyxia neonatorum was diagnosed if APGAR at birth and/or at 5 minutes was < 7. All the outcomes were then compared between mothers forming ‘Thick’ and ‘Thin’ meconium cohort. Result: Of the 53 meconium-stained liquor, nearly half (49%) was with ‘Thick’ meconium and the half (51%) was with ‘Thin’ meconium. Approximately 85% of the neonates were delivered by lower uterine caesarean section (LUCS) and 80% of the neonates were asphyxiated at birth which reduced to 15.1% at 5 minutes. More than three-quarters (75.5%) of the neonates required resuscitation and 28.3% had respiratory distress syndrome (RDS). The incidences of asphyxia neonatorum, resuscitation needed and RDS were significantly higher in ‘Thick’ meconium cohort than those in ‘Thin’ meconium cohort with risks of having these conditions in the former cohort being 6(95% CI = 1.1–31.2), 4.5(95% CI = 1.1–18.9) and 4.2(95% CI = 1.1–15.7) times higher respectively than those in the latter cohort (p = 0.021, p = 0.031 and p = 0.026 respectively). Conclusion: Majority of the neonates born of mothers with thick meconium cohort are asphyxiated, need resuscitation and/or develop RDS. Asphyxia neonatorum, need for resuscitation and RDS are significantly higher in ‘Thick’ meconium cohort than those in ‘Thin’ meconium cohort with risks of having these conditions in the former cohort being several times higher than those in the latter cohort. Ibrahim Card Med J 2019; 9 (1&2): 67-73

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