Medial meniscus replacement by a fat pad autograft

Kohn, Dieter; Rudert, Maximilian; Wirth, Carl Joachim; Plitz, W.; Reiss, G; Maschek, H.

doi:10.1007/s002640050157

Cited by 55 publications

(28 citation statements)

References 29 publications

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“…These outcomes were poor with regard to biomechanical weakness. 32,33 Because combinative transplantation with collagen scaffold and IPFP showed good outcomes for partial defects, we are going to conduct further research using a large defect model and biomechanical analysis.…”

Section: Controlmentioning

confidence: 99%

A new method for meniscus repair using type I collagen scaffold and infrapatellar fat pad

et al. 2015

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Section: Controlmentioning

confidence: 99%

A new method for meniscus repair using type I collagen scaffold and infrapatellar fat pad

et al. 2015

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“…In the past, various tissues have been used in an attempt to replace missing meniscal tissue, including autologous tissues such as patellar, Achilles or semitendinosus tendon autograft (Johnson and Feagin 2000;Kohn 1993;Kohn et al 1992), fat pad autograft (Kohn et al 1997) and autologous rib perichondral grafts (Bruns et al 1998), as well as synthetic silastic (Kenny et al 1983), carbon fibre (Veth et al 1983), Dacron (Sommerlath and Gillquist 1992) and Teflon (Messner 1994) prostheses. These various innovations have, unfortunately, met fairly universally with poor results.…”

Section: The History and Results Of Meniscal Transplantationmentioning

confidence: 99%

What tissue bankers should know about the use of allograft meniscus in orthopaedics

McDermott

2009

Cell Tissue Bank

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The menisci of the knee are two crescent shaped cartilage shock absorbers sitting between the femur and the tibia, which act as load sharers and shock absorbers. Loss of a meniscus leads to a significant increase in the risk of developing arthritis in the knee. Replacement of a missing meniscus with allograft tissue can reduce symptoms and may potentially reduce the risk of future arthritis. Meniscal allograft transplantation is a complex surgical procedure with many outstanding issues, including 'what techniques should be used for processing and storing grafts?', 'how should the allografts be sized?' and 'what surgical implantation techniques might be most appropriate?' Further clinical research is needed and close collaboration between the users (surgeons) and the suppliers (tissue banks) is essential. This review explores the above subject in detail.

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“…Not only is our algorithm useful in the short term for the selection of meniscal allografts, but also the algorithm will be useful in the long term for the selection of meniscal replacements other than allografts, including collagen scaffolds, 22 prosthetic menisci constructed from either Dacron, 23,24 Teflon 23 or porous polyurethane, 25 autologous fat pads, 26 small intestinal submucosa, 27 and autologous perichondral tissue. 28 Of these, only collagen scaffolds have been tested in humans to date with some promising results, 22 while the others are more preliminary with testing restricted to animal models.…”

Section: Discussionmentioning

confidence: 99%

New algorithm for selecting meniscal allografts that best match the size and shape of the damaged meniscus

2006

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Procedures used by tissue banks in selecting meniscal allografts that will best restore normal contact pressure at the time of surgical implantation into a recipient's knee should be improved. Our objective was to develop regression equations that use dimensions measured from magnetic resonance (MR) images of the contralateral knee to predict values of important meniscal parameters of the injured knee. Another objective was to incorporate these equations into an algorithm for selecting allografts that best match the size and shape of the damaged meniscus (either medial or lateral). In each of 10 knee specimens, four transverse and six cross-sectional parameters of the medial and lateral menisci were quantified from measurements obtained using a laser-based, noncontacting, 3-D coordinate digitizing system. In each of 10 contralateral knee specimens, six transverse and 24 cross-sectional (i.e., perpendicular to transverse plane) dimensions were measured for the medial and lateral menisci from MR images of each knee specimen. Simple linear regression equations related these 10 parameters to each of 38 predictor variables determined from magnetic resonance imaging (MRI) dimensions and the best regression equation for each parameter was identified. Requiring only 9 of the 30 dimensions as predictor variables, the best regression equations predicted 8 of 10 and 10 of 10 medial and lateral menisci parameters, respectively, with R 2 values >0.500. The algorithm for selecting meniscal allografts involves: collecting an inventory of meniscal allografts and determining the 10 meniscus parameter values for all allografts in the inventory; measuring the dimensions as required from MRI scans of the uninjured knee; using the dimensions as inputs to the regression equations to predict values of meniscal parameters; and selecting the meniscal allograft from the inventory that best matches the predicted values of meniscal parameters. Selecting meniscal allografts using our new algorithm may enable allografts to better meet the clinical objectives of meniscal transplantation, which are to reduce pain in some patients following meniscal resection and to inhibit the degeneration of the articular cartilage.

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Medial meniscus replacement by a fat pad autograft

Cited by 55 publications

References 29 publications

A new method for meniscus repair using type I collagen scaffold and infrapatellar fat pad

A new method for meniscus repair using type I collagen scaffold and infrapatellar fat pad

What tissue bankers should know about the use of allograft meniscus in orthopaedics

New algorithm for selecting meniscal allografts that best match the size and shape of the damaged meniscus

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