Median Raphe Cysts of the Penis

A case of epidermoid median raphe cyst traversing the corpora cavernosa

“…1 Another theory is that the cysts develop from abnormal closure of the median raphe and urethral groove. 2 Histologically, there are three patterns: urethral type, lined with pseudostratified columnar epithelium; epidermoid type, lined with squamous stratified epithelium; and mixed type, which incorporates both types of epithelium. 3 We suggest that our patient had an epidermoid type of median raphe cyst.…”

Median raphe cyst on the scrotum and perineum

“…1 Some canals have been successfully treated by marsupialization or by surgical incision followed by electrosurgical destruction of the epithelial lining. 1,5 In our case, the parents refused any treatment because of his age. To the Editor: Botulinum toxin type A (BTX-A) is known to inhibit acetylcholine release in eccrine sweat glands, and is an effective therapy for primary …”

“…Two proposed explanations as to its origin are as follows: (1) they arise from epithelial rests incidental to incomplete closure of the urethral or genital folds; or (2) they develop from split-off outgrowths of embryologic epithelium after primary closure of the folds. 5 Previously reported cases demonstrated perineal nodules without involvement of the scrotum and perineum. Our case had distinct clinical features of papules on the scrotum and perineum.…”

Pigmented Median Raphe Cysts of the Penis

“…The ®rst possible explanation is embryologic defective closure of the median raphe (7). The second theory is anomalous development of ectopic periurethral glands of Littre (8).…”