Medical Etiologies of Secondary Psychosis in Children and Adolescents

Merritt, Jessica; Tanguturi, Yasas; Fuchs, Cathérine; Cundiff, Allyson Witters

doi:10.1016/j.chc.2019.08.005

Cited by 13 publications

(10 citation statements)

References 55 publications

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“…Among infectious disorders initially presenting as psychosis, neurocysticercosis with multifocal scolex localizations was recurrently reported (Miranda 2020;Verma and Kumar 2013;Mahajan et al 2004), although almost any pathogen can be associated with psychotic symptoms (J. Merritt et al 2020). Beside direct neurological lesions, immune-and inflammatory-related injuries are probably involved in psychosis' pathophysiology, as suggested by the frequent association between primary psychoses and inflammatory infectious or auto-immune disorders (Cullen et al 2019;Khandaker et al 2015).…”

Section: In Secondary Psychosismentioning

confidence: 99%

Brain anomalies in early psychosis: From secondary to primary psychosis

Iftimovici

Chaumette

Duchesnay

et al. 2022

Neuroscience & Biobehavioral Reviews

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Section: In Secondary Psychosismentioning

confidence: 99%

Brain anomalies in early psychosis: From secondary to primary psychosis

Iftimovici

Chaumette

Duchesnay

et al. 2022

Neuroscience & Biobehavioral Reviews

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“…See Table 2 for a list of medical illnesses for which symptoms can include psychosis. [67][68][69] Environmental Exposure…”

Section: Genetic Factorsmentioning

confidence: 99%

“…112 See Table 2 for a list of medical illnesses, the symptoms of which can include psychosis, and recommended testing. [67][68][69] There is limited evidence supporting imaging studies for patients who do not present with associated focal neurologic signs, although it may be helpful in those with a history of head trauma. 30 Patients with positive antinuclear antibody titers should be referred to pediatric rheumatology, and neuroimaging studies should be performed for evaluation of possible lupus cerebritis.…”

Section: Laboratory and Imaging Studiesmentioning

confidence: 99%

Collaborative Care in the Identification and Management of Psychosis in Adolescents and Young Adults

Hua

2021

Pediatrics

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Pediatricians are often the first physicians to encounter adolescents and young adults presenting with psychotic symptoms. Although pediatricians would ideally be able to refer these patients immediately into psychiatric care, the shortage of child and adolescent psychiatry services may sometimes require pediatricians to make an initial assessment or continue care after recommendations are made by a specialist. Knowing how to identify and further evaluate these symptoms in pediatric patients and how to collaborate with and refer to specialty care is critical in helping to minimize the duration of untreated psychosis and to optimize outcomes. Because not all patients presenting with psychotic-like symptoms will convert to a psychotic disorder, pediatricians should avoid prematurely assigning a diagnosis when possible. Other contributing factors, such as co-occurring substance abuse or trauma, should also be considered. This clinical report describes psychotic and psychotic-like symptoms in the pediatric age group as well as etiology, risk factors, and recommendations for pediatricians, who may be among the first health care providers to identify youth at risk.

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“…Although relevant guidelines for organicity investigations are available [ 1 , 3 , 5 , 6 ], many of the disorders present without easily recognized phenotypes and are thus easily missed [ 7 ]. Nevertheless, it is important to ensure these diagnoses are made, because even if most of psychoses of organic origins remain inaccessible to specific treatment, some can benefit from suitable treatment and significant clinical improvement [ 8 ]. Diagnosing medical and genetic causes and risk factors of early psychosis is a challenge [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Implementing organicity investigations in early psychosis: Spreading expertise

Kurukgy

Bourgin²,

Benoı̂t

et al. 2021

PLoS ONE

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Background Many medical disorders may contribute to adolescent psychoses. Although guidelines for thorough organicity investigations (OI) exist, their dissemination appears scarce in nonacademic healthcare facilities and some rare disorders remain undiagnosed, many of them presenting without easily recognized phenotypes. This study aims to understand the challenges underlying the implementation of OI in non-academic facilities by practitioners trained in expert centers. Methods Sixteen psychiatrists working at French non-academic facilities were interviewed about their use of OI for adolescents suspected of early psychosis. Interviews were analyzed with Grounded Theory. Results Organicity investigations were found to be useful in rationalizing psychiatric care for the young patient all the while building trust between the doctor and the patient’s parents. They also are reassuring for psychiatrists confronted with uncertainty about psychosis onset and the consequences of a psychiatric label. However, they commonly find themselves facing the challenges of implementation alone and thus enter a renunciation pathway: from idealistic missionaries, they become torn between their professional ethics and the non-academic work culture. Ultimately, they abandon the use of OI or delegate it to expert centers. Conclusion Specific hindrances to OI implementation must be addressed.

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Medical Etiologies of Secondary Psychosis in Children and Adolescents

Cited by 13 publications

References 55 publications

Brain anomalies in early psychosis: From secondary to primary psychosis

Brain anomalies in early psychosis: From secondary to primary psychosis

Collaborative Care in the Identification and Management of Psychosis in Adolescents and Young Adults

Implementing organicity investigations in early psychosis: Spreading expertise

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