Medical Management of Blepharitis

Hakim, Farida; Farooq, Asim V.

doi:10.1007/978-3-030-65040-7_6

Cited by 3 publications

(2 citation statements)

References 35 publications

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“…1 Blepharitis is classified as anterior or posterior according to anatomical location, although the two types overlap and are often present together. 2 In anterior blepharitis outer edge of the eyelid margin that is eyelid skin and eyelash follicles are affected due to Staphylococcal Infection or seborrhoea. In posterior Blepharitis inner edge of the eye lid is affected due to meibomian gland dysfunction and alternations in meibomian gland secretions.…”

Section: Introductionmentioning

confidence: 99%

Frequency and Antibiotic Susceptibility of Bacteria Isolated in Patients with Blepharitis

Mahmood,

Muhammad Shahid,

Faisal Hanif

et al. 2023

PAFMJ

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Objective: To determine the frequency and antibiotic susceptibility of bacteria isolated in patients with blepharitis. StudyDesign: Cross-sectional study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi Pakistan, from Oct 2019 to Oct 2021. Methdology: 160 cases of blepharitis, during a period of 2 years, who were not using topical or systemic antibiotics were recruited in this cross-sectional study. After detailed history and slit-lamp examination of eyelids and tears film each patient underwent sample collection under aseptic conditions, from the eyelid margin. The samples were inoculated in a culture of blood agar and chocolate agar (Biomeriux) , Then the susceptibility of the identified bacteria to common systemic and topical antibiotics were tested using the disc diffusion method (Rosco Neo-Sensitab). Results: In 160 patients,118(73.7%) were males and 42(26.3%) were females. According to type of blepharitis, 98(61.3%) had posterior blepharitis and 62(38.7%) had anterior blepharitis.Culture of eyelid sample of 77(48.1%) patients showed growth of coagulase-negative staphylococcus Coagulase-negative staphylococcus (CoNS) show greater resistance towards Penicillin 77(100%), Ciprofloxacin 55(72.5%) and Erythromycin 33(42.8%) however more susceptibility was shown towards Linezolid (CoNS). 71(45%) had Staphylococcus aureus isolated from their culture. 77(100%),Vancomycin 77(100%), Gentamycin 66(85.8%), Chloramphenicol 56(74.5%) and Cotrimoxazole 55(72.5%).Staphylococcus aureus show greater resistance towards Penicillin 72(100%),Ciprofloxacin 41(56.9%) and Tetracyclins 30(41.6%) however more susceptibility was found towards Gentamycin 72(100%), Linezolid 72(100%),Vancomycin 72(100%) and Chloramphenicol 61(84.7%). Conclusion: Coagulase-negative staphylococcus (CoNS) and Staphylococcus aureus have been the main isolated organisms in blepharitis. These bacteria have been shown to be resistant to Penicillin,

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Section: Introductionmentioning

confidence: 99%

Frequency and Antibiotic Susceptibility of Bacteria Isolated in Patients with Blepharitis

Mahmood,

Muhammad Shahid,

Faisal Hanif

et al. 2023

PAFMJ

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“…Treatment goals in blepharitis are decreasing symptoms, the number of bacteria in eyelid margins and inflammation as well as improving the function of meibomian gland that are achieved through washing and warm compress of eyelids, and the use of anti-inflammatory and antibacterial agents such as erythromycin, tobramycin, cyclosporine, local dexamethasone, and oral doxycycline [8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

The Efficacy of Kohl (Surma) and Erythromycin in Treatment of Blepharitis: An Open-Label Clinical Trial

Karbassi

Amiri‐Ardekani

Farsinezhad

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Introduction. Blepharitis is a common and chronic form of eyelid inflammation. Blepharitis treatment aims to decrease symptoms through antibacterial effects. One of the most common treatments of eyelid diseases in traditional medicine is using kohl. This clinical trial aimed to investigate its efficacy as a complementary treatment in staphylococcal blepharitis through an open-label clinical trial. Materials and Methods. Thirty patients were randomized to receive kohl in one eye contralateral and erythromycin ointment in another eye for 90 days. At baseline and after 90 days of treatment, symptoms, clinical signs, and side effects of treatments were recorded. Statistical analysis was carried out using SPSS software, version 19. Results. Despite randomization, there was a significant difference between the intervention and control eyes in the baseline mean clinical score (intervention eye: 9.86 (2.95) and control eye: 4.30 (2.81), P < 0.001 ). The degree of reduction of related signs and symptoms in the eyes treated with kohl was significantly higher than that in the control group: (5.2 vs. 2.20, P < 0.001 ) for symptoms and (7.40 vs. 2.46, P < 0.001 ) for clinical signs. Cohen’s d statistic for mean difference of sign and symptom was 2.4 and 1.75, respectively, indicating a very strong effect. Conclusion. The present study results demonstrated a significant improvement in blepharitis-related signs and symptoms. The degree of improvement in the eyes treated with kohl was much higher than that in the control eyes.

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Tear Film Lipid Layer Changes Following Combined Effect of Heated Eye Mask with Intense Pulsed Light Therapy for Evaporative Dry Eye: A Randomized Control Study

Li,

Chen,

Qin

et al. 2023

Photobiomodulation, Photomedicine, and Laser Surgery

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Medical Management of Blepharitis

Cited by 3 publications

References 35 publications

Frequency and Antibiotic Susceptibility of Bacteria Isolated in Patients with Blepharitis

Frequency and Antibiotic Susceptibility of Bacteria Isolated in Patients with Blepharitis

The Efficacy of Kohl (Surma) and Erythromycin in Treatment of Blepharitis: An Open-Label Clinical Trial

Tear Film Lipid Layer Changes Following Combined Effect of Heated Eye Mask with Intense Pulsed Light Therapy for Evaporative Dry Eye: A Randomized Control Study

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