Medical vs. surgical treatment for clomiphene citrate-resistant women with polycystic ovary syndrome

Malkawi, H. Y.; Qublan, Hussein S.; Hamaideh, A. H.

doi:10.1080/01443610306068

Cited by 22 publications

(40 citation statements)

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“…Two studies in the literature compared metformin with LOD in CC-resistant patients without considering insulin resistance as a prerequisite, and the results were conflicting [11,12]. In the first study [11], no significant difference was found in the ovulation or pregnancy rates between patients who received metformin or LOD; however, the second study reported a higher pregnancy rate in the metformin group [12].…”

Section: Introductionmentioning

confidence: 93%

Retracted: Metformin versus laparoscopic ovarian drilling in clomiphene‐ and insulin‐resistant women with polycystic ovary syndrome

Hamed

Hasan

Ahmed

et al. 2009

Intl J Gynecology & Obste

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Section: Introductionmentioning

confidence: 93%

Retracted: Metformin versus laparoscopic ovarian drilling in clomiphene‐ and insulin‐resistant women with polycystic ovary syndrome

Hamed

Hasan

Ahmed

et al. 2009

Intl J Gynecology & Obste

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“…20 Malkawi et al reported, 83.5% ovulation rate in LOD plus CC group and successful ovulation rate of 70.6% and 66.7% with human menopausal gonadotropins (hMG) and pure follicle stimulating hormone (FSH) respectively. 21,22 In present study, inGroup A, out of 12 ovulated women in 1st cycle, 1 (8.3%) got pregnant. In 2 nd cycle of CC, out of total 12 ovulated women, 3 (25%) got pregnant.…”

Section: Resultsmentioning

confidence: 99%

Comparison of clinical outcomes in clomiphene citrate resistant infertile polycystic ovarian syndrome women after treatment with laparoscopic ovarian drilling (LOD) versus gonadotropins

Rupa

Jain

Dutta

et al. 2018

Int J Reprod Contracept Obstet Gynecol

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Background: Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year. Objective of present study was to compare the clinical outcome of laparoscopic ovarian drilling with gonadotropin ovulation induction in patients with clomiphene resistant Polycystic Ovarian Syndrome.Methods: Present study was a comparative interventional study conducted at the Institute of Obstetrics and Gynaecology, Sir Ganga Ram Hospital, New Delhi for a period of one and a half year. We enrolled 40 clomiphene citrate resistant infertile PCOS women who were undergoing treatment for infertility, after taking written informed consent. The women were randomly divided into two equal groups: one for LOD (laparoscopic ovarian drilling) (group A) and other for gonadotropins (group B).Results: Out of 20, 16 women (80%) in group A ovulated with clomiphene citrate and 18 women (90%) ovulated in group B. Pregnancy was the second major outcome and 4 women (20%) in group A with clomiphene citrate got pregnant and 9 women (45%) got pregnant in group B.Conclusions: Out of 20, 16 women (80%) in group A ovulated with clomiphene citrate and 18 women (90%) ovulated in group B. Pregnancy was the second major outcome and 4 women (20%) in group A with clomiphene citrate got pregnant and 9 women (45%) got pregnant in group B. The treatment option can be selected and tailored according to the individual needs and desires of the patient.

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“…Most investigators use between 4 and 10 punctures; more punctures have been associated with premature ovarian failure (120)(121)(122). As in all surgical procedures, an important issue of successful outcome is the expertise of the surgeon.…”

Section: Methods and Dosementioning

confidence: 99%

Consensus on infertility treatment related to polycystic ovary syndrome

Thessaloniki¹,

Greece²

2008

Fertility and Sterility

621

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Medical vs. surgical treatment for clomiphene citrate-resistant women with polycystic ovary syndrome

Cited by 22 publications

References 0 publications

Retracted: Metformin versus laparoscopic ovarian drilling in clomiphene‐ and insulin‐resistant women with polycystic ovary syndrome

Retracted: Metformin versus laparoscopic ovarian drilling in clomiphene‐ and insulin‐resistant women with polycystic ovary syndrome

Comparison of clinical outcomes in clomiphene citrate resistant infertile polycystic ovarian syndrome women after treatment with laparoscopic ovarian drilling (LOD) versus gonadotropins

Consensus on infertility treatment related to polycystic ovary syndrome

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