Medically sound, cost-effective treatment for pelvic inflammatory disease and tuboovarian abscess

McNeeley, S. Gene; Hendrix, Susan L.; Mazzoni, Marcel M.; Kmak, David; Ransom, Scott B.

doi:10.1016/s0002-9378(98)70333-3

Cited by 123 publications

(72 citation statements)

References 10 publications

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“…Tubo-ovarian abscesses (TOAs) are classically treated with intravenous followed by oral antibiotics over a prolonged period 1 . The response rate to antimicrobial treatment alone is about 70%.…”

Section: Introductionmentioning

confidence: 99%

Comparison of CT‐ or ultrasound‐guided drainage with concomitant intravenous antibiotics vs. intravenous antibiotics alone in the management of tubo‐ovarian abscesses

Goharkhay

Verma

Maggiorotto

2006

Ultrasound in Obstet & Gyne

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Section: Introductionmentioning

confidence: 99%

Comparison of CT‐ or ultrasound‐guided drainage with concomitant intravenous antibiotics vs. intravenous antibiotics alone in the management of tubo‐ovarian abscesses

Goharkhay

Verma

Maggiorotto

2006

Ultrasound in Obstet & Gyne

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“…After persistent fever or pain, ampicillin was added to their regimen. Some studies indicate that ampicillin, gentamicin, and clindamycin are superior to a gentamicin and clindamycin regimen [6]. Starting with triple antibiotics may thus provide optimal treatment and decrease hospital stay.…”

Section: Discussionmentioning

confidence: 99%

“…A single agent broad-spectrum antibiotic (i.e., cefoxitin) plus doxycycline has shown a 75% clinical response rate, equivalent to that of a clindamycin and aminoglycoside regimen [5]. However, other studies suggest that a triple antibiotic regimen (i.e., ampicillin, gentamicin, and clindamycin) is superior, with an 85% cure rate [6]. No official recommendation exists, leaving institution and provider preference as the determinant in treatment selection.…”

Section: Introductionmentioning

confidence: 99%

Surgical, Ultrasound Guided Drainage, and Medical Management of Tuboovarian Abscesses

Crespo

Ganesh

et al. 2014

ISRN Infectious Diseases

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Objective. To compare surgical, ultrasound guided drainage, and medical management of tuboovarian abscesses (TOA) and determine if different characteristics in patient presentation influence treatment and outcome. Methods. Retrospective cohort study of 158 patients admitted to Jackson Memorial Hospital between 2007 and 2012 with a TOA. Results. Patients treated with IV antibiotics (IV) alone were hospitalized for 5.59 days (SD 2.52), IV antibiotics and US guided drainage (IV/US) were hospitalized for 9.63 days (SD 7.58), and IV antibiotics and surgery (IV/surgery) were hospitalized for 8.14 days ((SD 3.9), ( < 0.001)). A total of 52 patients were readmitted with TOA; 41.8% were treated with IV; 26.9% were readmitted with IV/US; 7.1% were readmitted with IV/surgery ( < 0.022). Patients with a TOA measuring 0-8 cm were hospitalized for 5.97 days (SD 4.24), while those greater than 8 cm were hospitalized for 7.71 days ((SD 4.69), ( < 0.029)). Patients treated with a triple antibiotic regimen were hospitalized for 8.42 days (SD 5.70) versus 5.8 days (SD 3.24) when receiving an alternative regimen ( < 0.002). Conclusions. Longer hospitalization in patients treated uniformly with either triple antibiotics, ultrasound guided drainage, or surgery represents a delay in optimal treatment. Tailoring treatment plans based on patient presentation may allow for shorter hospital stays and improved morbidity.

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“…Failure to respond to medical therapy is suggested by lack of defervescence within 72 hours or an increase in size of mass.Eightyfive percent of abscesses with a diameter of 4 to 6 cm respond to antibiotics alone, but only 40% of those 10 cm or larger respond. Triple-agent therapy with ampicillin.clindamycin,and gentamycin would seem to be the regimen of choice, although other combination regimens have been used effectively [27,28].Surgical intervention for tuboovarian abscess that does not respond to antimicrobial therapy can be performed laproscopically,percutaneously,or transvaginally or by laparotomy. A patient with a suspected leaking or ruptured abscess should undergo immediate surgical exploration after rapid stabilization and institution of broad spectrum antibiotics [29].…”

Section: Tuboovarian Abscessmentioning

confidence: 99%

Pelvic Inflammatory Disease: Current notions

Mustafa¹,

Yanggau²,

Lasimbang³

et al. 2014

IJPSI

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Medically sound, cost-effective treatment for pelvic inflammatory disease and tuboovarian abscess

Cited by 123 publications

References 10 publications

Comparison of CT‐ or ultrasound‐guided drainage with concomitant intravenous antibiotics vs. intravenous antibiotics alone in the management of tubo‐ovarian abscesses

Comparison of CT‐ or ultrasound‐guided drainage with concomitant intravenous antibiotics vs. intravenous antibiotics alone in the management of tubo‐ovarian abscesses

Surgical, Ultrasound Guided Drainage, and Medical Management of Tuboovarian Abscesses

Pelvic Inflammatory Disease: Current notions

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