Medicated Chewing Gum is an Excellent Drug Delivery System for Self Medication

Khairnar, Dhiraj A.; Darekar, A. B.; Saudagar, R. B.

doi:10.5958/2231-5713.2016.00004.0

Cited by 6 publications

(3 citation statements)

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“…The tensile testing machine is set for the determination of force-elongation properties. Engineering stress and strain are obtained as describe below [44]: The first part of the curve obeys Hook's law where the ratio of stress to strain is constant, and a linear relationship can be observed.…”

Section: Mechanical Propertiesmentioning

confidence: 99%

Recent Formulation Development Advances and Drug Delivery Insights for Medicated Chewing Gums

Sahu¹,

Prasad²

2023

IJMPS

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Oral medication delivery system research has resulted in the development of new formulations and technology. Such studies demonstrate the importance of the oral route among patients. We’ve gone through all of the benefits and drawbacks of medicated chewing gum as a contemporary medication delivery system, including the history, benefits and drawbacks, production processes, composition variations, assessment tests, and samples of different medicated chewing gum kinds. The acceptance of medicated chewing gum has grown over time. Chewing gum’s advantages and therapeutic benefits encourage its development, as shown by the fact that new formulations including new pharmaceuticals have been generated in the past and will be found in the market by the formation of new medicated chewing gums. Medicated chewing gums have a broad range of potential uses that will be identified in the future. Chewing gums now have the same qualification criteria as pills. Patients’ compliance is improved by using medicated chewing gums as a delivery strategy in patient-centered research.

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Section: Mechanical Propertiesmentioning

confidence: 99%

Recent Formulation Development Advances and Drug Delivery Insights for Medicated Chewing Gums

Sahu¹,

Prasad²

2023

IJMPS

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“…By adding elastomer solvent to the gum base, the Tg is desirably changed, but not more than ±3°C (Miladinov & Amarista, 2007), and therefore, the elasticity, cohesion, and softness of the gum base are improved. Elastomer solvents act as a connector between elastomers and other materials and maintain the balance between the elastic and plastic traits of the gum base (Khairnar et al, 2016). Also, they enhance the texture of the gum base to achieve better chewing traits and a superior mouthfeel.…”

Section: Gum Base Compositionsmentioning

confidence: 99%

Chewing gum base: A comprehensive review of composition, production, and assessment methods: Advances and approaches in biodegradability

kaveh¹,

Yeganehzad²,

Ashkezary

et al. 2023

Journal of Texture Studies

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The gum base mass is a colloidal system and the main component of chewing gum; which is an inert, non‐nutritious, indigestible, and insoluble part of chewing gum, therefore this substance does not dissolve in the mouth when chewed. The gum base plays the most crucial role in determining the mechanical properties, flexibility, and overall quality of chewing gum. Moreover, it acts as a delivery system to transport sweeteners, flavorings, and other ingredients in chewing gum. Despite the massive market for chewing gum and the provision of a list of the main ingredients in gum base by the Code of Federal Regulations and some international organizations, there is a lack of information about chewing gum base and its compositions in the literature. Therefore, the purpose of this review is to present an overview of the characteristics, ingredients and applications, production process, assessment, and modification methods of the gum base along with the advances and approaches in biodegradability. Biodegradability concerns play a promoting role in the research and development of chewing gum and its applications in the food industry, medical and dental sectors. Reviewing previous studies can surely help for faster development of this path.

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“…The formulation of chewing gum of antidepressant will enhance the patient's compliance by providing the systemic effect immediately by directly affecting the central nervous system 13,14 . There are various case studies and clinical trials done for chewing gum and concluded by higher patient compliance 11,18,24 . Hence, the objective of the research work is to formulate a venlafaxinecontaining medicated chewing gum that has greater bioavailability and compliances than conventional treatment strategies.…”

Section: Quick Response Codementioning

confidence: 99%

Untitled

2021

IJPSR

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The objective of research work is to formulate a venlafaxine HCl containing medicated chewing gum that has greater bioavailability and compliances than conventional treatment strategies. The four different formulations were prepared after some trial batches, containing different concentrations of the gum base and sucrose (MCG-I-MCG-IV). These batches were optimized on basis of softness and sweetness. Batch MCG-II was found to be optimized containing 60% gum base and 15% of sucrose. Further batches were characterized on basis of Physical characterization, texture analysis, drug content and in-vitro drug release. All batches show good color, softness, and taste. Drug content was found out in a range of 98.43-99.24%. The in-vitro drug release data revealed that MCG-II shows better drug release than other formulations. Medicated chewing gum can be a better choice for the treatment of depression in the coming years, which may provide several benefits to patient.

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Medicated Chewing Gum is an Excellent Drug Delivery System for Self Medication

Cited by 6 publications

References 0 publications

Recent Formulation Development Advances and Drug Delivery Insights for Medicated Chewing Gums

Recent Formulation Development Advances and Drug Delivery Insights for Medicated Chewing Gums

Chewing gum base: A comprehensive review of composition, production, and assessment methods: Advances and approaches in biodegradability

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