Medication adherence and influencing factors in patients with type 2 diabetes attending a tertiary hospital in South-West Nigeria

Onwuchuluba, E.; Soremekun, Rebecca; Oyetunde, Olubukola O.

doi:10.4103/jcls.jcls_40_19

Cited by 6 publications

(9 citation statements)

References 22 publications

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“…The cost of insulin for low wage earners may be responsible for its lower uptake in this study. A similar trend was observed in Lagos, Nigeria where many people do not receive insulin therapy, 35 but this finding was opposite to that of a study in Ethiopia, where most (47.0%) respondents were on insulin therapy. 36 Commencement of insulin therapy once OHAs have failed has long been recommended in the treatment guidelines.…”

Section: Discussionsupporting

confidence: 42%

“…9,39 In contrast, Onwuchuluba et al found no significant relationship between adherence and glycemic control. 35 Adherence in this study (62.0%) was relatively good given that the reported medication adherence with a chronic medical condition is approximately 30% to 50%. 37 Patients with T2DM and comorbid conditions require multiple medications and a high adherence rate to achieve good glycemic control, as observed in this study and reported in other studies.…”

Section: Discussionmentioning

confidence: 67%

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Glycemic control and its association with sociodemographics, comorbid conditions, and medication adherence among patients with type 2 diabetes in southwestern Nigeria

Ibrahim¹,

Agboola

Elegbede

et al. 2021

J Int Med Res

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Objective We determined the prevalence of poor glycemic control and associations with sociodemographics, comorbid conditions, and medication adherence among patients with type 2 diabetes mellitus (T2DM) at a tertiary hospital in southwestern Nigeria. Methods We conducted a retrospective observational study among 300 patients with T2DM using systematic random sampling. We used a semi-structured questionnaire to collect information on respondents’ sociodemographic profile, lifestyle, comorbid conditions, and antidiabetic medications. Adherence was determined using the Morisky Medication Adherence Scale. Fasting blood samples were tested using a glycated hemoglobin marker. Multivariate logistic regression was used to identify factors associated with poor glycemic control. Results Respondents’ mean age was 61.9 ± 11.8 years. The prevalence of poor glycemic control was 40.0% (95% confidence interval [CI]: 34.4%–45.8%). The adjusted odds ratio (95% CI) for factors associated with poor glycemic control was 2.522 (1.402–4.647) for older age, 1.882 (1.021–3.467) for low income, 1.734 (1.013–3.401) for obesity, 2.014 (1.269–5.336) for non-initiation of insulin therapy, and 1.830 (1.045–3.206) for poor medication adherence. Conclusion Older age, lower income, obesity, non-initiation of insulin, and poor medication adherence were associated with poor glycemic control. These variables may help clinicians identify patients at high risk of poor glycemic control.

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Section: Discussionsupporting

confidence: 42%

Section: Discussionmentioning

confidence: 67%

Glycemic control and its association with sociodemographics, comorbid conditions, and medication adherence among patients with type 2 diabetes in southwestern Nigeria

Ibrahim¹,

Agboola

Elegbede

et al. 2021

J Int Med Res

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show abstract

“…These studies demonstrate the importance of medication adherence even in the elderly diabetic patient. However, from a study by Onwuchuluba et al [49] no association was found between medication adherence and good glycaemic control. This difference may be a reflection of the fact that adherence to medication may not be the only factor that contributes to improved glycaemic control even among elderly patients; a concept that gave rise to this study which aimed at identifying other factors that may be associated with improved glycaemic control aside from medication adherence.…”

Section: Discussionmentioning

confidence: 89%

Glycemic Control and its Associated Factors among Elderly Diabetic Patients in a Tertiary Hospital in Lagos, Nigeria

Angela¹,

Mirian

Nneamaka³

2022

CRDOJ

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Background: Glycaemic control in the elderly diabetic patient is highly individualized and achieving desired targets in the presence of comorbid conditions could be very challenging. This study was conducted to assess the glycemic control of elderly diabetics and identify associated factors at the Lagos University Teaching Hospital (LUTH). Methods: A hospital-based, cross-sectional descriptive study involving 199 randomly selected elderly diabetic patients receiving care at LUTH. A pretested, interviewer-administered questionnaire was used in data collection, which include sociodemographic characteristics, clinical history, and glycaemic control. Glycemic control was assessed using glycated haemoglobin (HBA1C). HBA1C<7.0% was tight; 7-8% targeted and >8% poor glycaemic control. Associations between glycemic control and independent variables was assessed using the chi-square test and its predictors identified by logistic regression analysis. Level of significance was set at p<0.05. Results: The mean age of the participants was 68.6 years ± 6.7 years. Tight and poor glycemic control was seen in 35.1% and 34.2% respectively. Significant associations existed between glycemic control, age (ꭓ2 =9.310; p – 0.010), and marital status (ꭓ2 = 9.934; p – 0.007). Independent predictors include >2 antidiabetic medication (aOR – 2.55; p – 0.048) Conclusion: Poor glycaemic control was high among the elderly and there was a negative correlation between age and glycaemic control among the participants. Statistically significant association was also found between glycaemic control and marital status of the participants as well as the number of diabetic medications, the presence of co-morbid conditions and adherence to medications. The need for individualized care among elderly diabetics cannot be overemphasized in order to reduce the risk of hypoglycaemia, improve clinical outcome, while considering other factors which could have an impact on glycaemic control among the elderly.

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“…1 It comprises of several sub-classification among which is type 2 diabetes mellitus. Although it is a preventable disease, high prevalence has been reported in various parts of Nigeria, with alarm of impending epidemic, 2 , 3 , 4 , 5 and this has been attributed to increased urbanization and its associated lifestyle changes. 2…”

Section: Introductionmentioning

confidence: 99%

Drug therapy and medication adherence in type 2 diabetes in a care facility: A cross sectional survey

Eze

Akhumi

Iheanacho

et al. 2022

Exploratory Research in Clinical and Social Pharmacy

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Medication adherence and influencing factors in patients with type 2 diabetes attending a tertiary hospital in South-West Nigeria

Cited by 6 publications

References 22 publications

Glycemic control and its association with sociodemographics, comorbid conditions, and medication adherence among patients with type 2 diabetes in southwestern Nigeria

Glycemic control and its association with sociodemographics, comorbid conditions, and medication adherence among patients with type 2 diabetes in southwestern Nigeria

Glycemic Control and its Associated Factors among Elderly Diabetic Patients in a Tertiary Hospital in Lagos, Nigeria

Drug therapy and medication adherence in type 2 diabetes in a care facility: A cross sectional survey

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