Medications in pregnancy and lactation

Della-Giustina, Karen; Chow, Greg

doi:10.1016/s0733-8627(03)00037-3

Cited by 38 publications

(24 citation statements)

References 70 publications

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“…General guidelines for physicians treating pregnant women are as follows: determine if the medication is necessary and choose the safest drug available (eg, diazepam, lorazepam, or clonazepam) at the lowest dosage for the shortest duration, avoiding during the first trimester if possible [70,72].…”

Section: Diet and Lifestylementioning

confidence: 99%

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Sleep problems across the life cycle in women

Moline

Broch²,

R³

2004

Curr Treat Options Neurol

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Across the life cycle of women, the quality and quantity of sleep can be markedly impacted by internal (eg, hormonal changes and vasomotor symptoms) and external (financial and child-care responsibilities; marital issue) factors. This paper will outline some of the major phases of the life cycle in women that have been associated with sleep problems. The main messages from this paper include 1) that very little systematic, large-scale research has been performed in virtually every area reviewed; and 2) once identified, the sleep problem is generally best addressed by the standard therapeutic approach, except in the case of pregnant and lactating women in which concern for the fetus and child must be considered in the treatment decision. This paper is organized into sections that address sleep problems associated with the menstrual cycle, pregnancy, postpartum, and perimenopause. Anecdotal reports recommend treatment that addresses the specific physical discomfort experienced by the woman (eg, analgesics for premenstrual pain, pregnancy pillows for backache, and hormone replacement therapy for hot flashes). The importance of developing standard treatment recommendations is stressed because the development of chronic insomnia has been linked to precipitating events. In addition, primary sleep disorders (eg, sleep apnea or restless legs syndrome) have been shown to increase during pregnancy and menopause, but treatment recommendations may be contraindicated or are not specific for women.

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Section: Diet and Lifestylementioning

confidence: 99%

“…• Suggest the mother seek assistance, especially early postpartum, so that fatigue may be mitigated. • General guidelines regarding medication during lactation include the following [72]: -Establish the risk/benefit ratio to determine if the medication is necessary.…”

Section: Diet and Lifestylementioning

confidence: 99%

Sleep problems across the life cycle in women

Moline

Broch²,

R³

2004

Curr Treat Options Neurol

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“…Оптимальная терапия вклю-чает оценку результатов непрерывного использования безопасных ЛС или прекращение использования либо небезопасных, либо несущественных медикаментов [8]. Наряду с этим следует отметить, что производители ред-ко рекомендуют разработанное ими ЛС использовать во время беременности и лактации [12]. Следовательно, термин «Противопоказание» в инструкции о применении ЛС не всегда отражает установленный для него терато-генный риск.…”

Section: информационное обеспечение доказательности безопасного исполunclassified

Safe Use of Drugs During Pregnancy in Focus of International Practice of Pharmacovigilance System and Teratological Information Service Organization

Луцевич¹,

Reshetko²,

Санина³

2012

Pediatr. farmakol.

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“…Each condition presents a distinctive set of problems. 4,5,6 It is well-established that all drugs are excreted into breast milk and are bioavailable to the infant. In general, the majority of drugs do not pose a significant problem to the nursing infant.…”

Section: Introductionmentioning

confidence: 99%

Use of Traditional Drugs in Pregnant and Nursing Mothers: A Review of Associated Adverse Drug Reactions

Hamiduddin¹,

Aslam²,

Sofi³

et al. 2016

J. Pharm. Sci. Innov.

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The condition of carrying a developing embryo in the uterus and breast feeding of baby by mothers requires special precautions in term of intake of medicines. Usage of traditional drugs also requires some vigilance in respects of its adverse drugs reactions. The particular dangers of these preparations come rather from the belief that they are natural and therefore necessarily safe in pregnancy. Since last few decades' tremendous research work has been done of the various aspect of medicinal plants on pharmacognostic and chemical aspect, but aspect of safety and toxicity particularly, in pregnancy and lactation, is the most neglected area. These medicines are considering safer then allopathic drugs, but several plant species are proven be toxic in these conditions. For example, volatile oil containing drugs can be abortifacient, Irritant to genitourinary tract (can cause uterine contractions). Some constituents also have got action on uterus. Pyrrolizidine alkaloids can cause Hepatotoxicity in a new born. Some are strong diuretic and laxative (can cause water / salt lose), hormonally active, mutagenic, ginotoxic, teratogenic, etc. So these drugs are better avoided during pregnancy and lactations. An attempt can be made to identify herbal / traditional ingredients that have potential toxic effect on pregnancy and lactating women and also about their potential interfere with specific categories of conventional drugs based on their phytochemical, pharmacological properties and many documented side effects and also due to adulteration by heavy metals & microbial contaminations in relevance with classical Unani & Ayurvedic / traditional literature. Details of these drugs will be discussed in the present work.

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Medications in pregnancy and lactation

Cited by 38 publications

References 70 publications

Sleep problems across the life cycle in women

Sleep problems across the life cycle in women

Safe Use of Drugs During Pregnancy in Focus of International Practice of Pharmacovigilance System and Teratological Information Service Organization

Use of Traditional Drugs in Pregnant and Nursing Mothers: A Review of Associated Adverse Drug Reactions

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