Medikamentöse Therapie der Angst bei Patienten mit fortgeschrittenen Tumorerkrankungen bzw. Patienten in der palliativen Situation

Abstract

With the existing evidence no general recommendations for pharmacological treatment of anxiety in palliative care can be given. Even for the commonly used benzodiazepines, neuroleptics, antidepressants, antihistamines and beta blockers for the treatment of anxiety no evidence based recommendations can be made. However, these medications are commonly used to treat anxiety in other patient populations and can also be used in palliative care patients. According to our review we cannot recommend a single drug or give recommendations regarding the dosage of drugs. There is a strong need for randomized controlled trials to evaluate the effect of drug treatment of anxiety in palliative care patients. The English full text version of this article will be available in SpringerLink as of November 2012 (under "Supplemental").

‘Worried to death’: the assessment and management of anxiety in patients with advanced life-limiting disease, a national survey of palliative medicine physicians

“…Also, as part of the statistical analysis multiple tests were carried out without adjustments as it was an exploratory analysis. Finally, the survey was conducted in 2014 and it is possible that there have been changes in practice since, particularly as new or updated guidelines (for cancer patients and the general population) were produced shortly before and after the data collection [ 18 – 20 , 24 ].…”

Guidance on Conducting and REporting DElphi Studies (CREDES) in palliative care: Recommendations based on a methodological systematic review

“…13–15 As a consequence, sparse evidence from RCTs and observational studies has been identified for relevant areas of symptom treatment. 16–21…”

MVP–Medical Situation, Values, and Plan: A Memorable and Useful Model for All Serious Illness Conversations

“… 20 , 33 Consequently, effective SICs require that clinicians continuously empathize, by which we mean anticipate, appreciate, validate, and explore the emotions the conversations evoke. 34 , 35 , 36 , 37 Although strong patient emotions are uncomfortable for most clinicians, it is neither empathic nor productive to comfort patients or family members by avoiding, minimizing, or suppressing them. On the contrary, strong emotions are to be expected, and they may actually be evidence of clinician authenticity, skill, and compassion.…”