Mediterranean Diet, Lifestyle and Quality of Life in Sardinian Patients Affected with Hidradenitis Suppurativa

Velluzzi, Fernanda; Anedda, Jasmine; Pisanu, Silvia; Dell'Antonia, Massimo; Deledda, Andrea; Boi, A.; Ferreli, Caterina; Atzori, Laura

doi:10.4081/jphr.2021.2706

Cited by 14 publications

(16 citation statements)

References 60 publications

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Section: Discussionsupporting

confidence: 86%

“…Similar to the findings of earlier literature, HS patients (= total group of assessed HS patients) had a higher BMI and waist circumference, but consumed less kilocalories and carbohydrates than the control group. 21 It is previously described that losing weight is more complex than solely lowering kilocalorie intake, which might contribute to the difference in the HS patients' low kilocalorie intake and inversely high BMI. 22,23 Other explanations for the high BMI and lower than expected kilocalorie intake of HS patients could be their higher consumption of artificially sweetened products (that can lead to the development of glucose intolerance), 24 lower levels of PA and possible self-(under)reporting of food intake.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Diet and physical activity as risk‐reducing factors for hidradenitis suppurativa

Bouwman,

Moazzen,

Kroah‐Hartman

et al. 2023

Acad Dermatol Venereol

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BackgroundHidradenitis suppurativa (HS) is a multifactorial inflammatory skin disease that is considered to be an immune‐mediated inflammatory disease (IMID). Up till now, the impact of lifestyle on (the development of) HS has not been thoroughly investigated.ObjectivesTo investigate the effect of dietary intake and physical activity (PA) on (the development of) HS.Materials and MethodsA nested case–control study was performed within the longitudinal Lifelines Cohort Study, that took place in the Northern Netherlands, and identified 1004 adult eligible HS patients and 5000 age‐matched controls. Dietary data were collected using a validated food frequency questionnaire, subsequently translated to the Lifelines Diet Score (LLDS), alternate Mediterranean Diet Score (aMED) and Dutch Dietary Guidelines score (DDG), with higher scores reflecting healthier dietary habits. PA was measured by the Short Questionnaire to Assess Health‐enhancing PA score. Logistic regression analyses were performed between dietary/PA scores, and the prevalence/development and severity of HS.ResultsCompared to controls, HS patients scored lower on the LLDS [OR = 0.98; 95% CI 0.96–0.99], aMED [0.93; 0.89–0.97] and DDG [0.93; 0.88–0.97] with multivariable regression analysis. Overall, this indicates less adherence to dietary recommendations and consumption of a low‐quality diet in the HS population. Lower adherence to the LLDS and DDG was also significantly associated with a higher likelihood to HS development in univariable regression analysis [0.96; 0.94–0.99 and 0.91; 0.84–0.99, respectively], and a trend of decreased adherence to the aMED [0.93; 0.85–1.02] was noted. Besides, PA levels were found significantly lower in HS patients (p ≤ 0.001).Conclusions and RelevancePoor diet quality and lower quantities of PA were associated with HS in the general population. Identifying dietary and PA habits of HS patients can contribute to the development of prevention strategies for HS specifically, and for IMIDs in general.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Diet and physical activity as risk‐reducing factors for hidradenitis suppurativa

Bouwman,

Moazzen,

Kroah‐Hartman

et al. 2023

Acad Dermatol Venereol

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“…In fact, MD represents a balanced nutritional model and is able to improve the lowgrade inflammation and the gut microbiota alterations typical of visceral obesity [76,77], MS, and non-communicable or inflammatory diseases [41,78,79].…”

Section: Discussionmentioning

confidence: 99%

Effect of a Low-Moderate Exercise Program on Dysmetabolism in Older Adults: Results of a Randomized Controlled Trial

et al. 2022

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Physical exercise has been shown to improve dysmetabolism in older adults, reducing cardiovascular risk, while its role in preventing dysmetabolism is less known. Moreover, most of the trials use exercise programs that are difficult to put into daily practice. The purpose of this Randomized Controlled Trial (RCT) was to evaluate the effectiveness of a 3-month moderate exercise program in improving or preventing dysmetabolism in 120 older adults, randomly selected for the exercise program (experimental group) or cultural activities (control group). None of the subjects were following a hypocaloric diet, and all of them reported healthy eating habits. Anthropometric (Body Mass Index (BMI) and Waist Circumference (WC)) and metabolic variables (fasting plasma glucose (FPG), High-Density Lipoprotein Cholesterol (HDL-C), and triglycerides (TG)) were assessed at baseline (T0) and at the end of the trial (T1). Dysmetabolism was defined by the presence of an increased WC plus at least two metabolic alterations. At T0, the two groups did not differ by sex, age, education, BMI, WC, FPG, HDL-C levels, and prevalence of dysmetabolism. The mean BMI value indicated overweight, and WC values were higher than the cut-off. At T1, a slight reduction in the number of people with dysmetabolism was found only in the experimental group. However, none of the individuals without dysmetabolism at T0 in the experimental group developed it at T1, while 11.4% developed it in the control group (p = 0.032). This study highlights that a moderate exercise program, accessible in daily practice, can prevent dysmetabolism in older adults, even while being overweight, while if dysmetabolism is already present, more prolonged combined nutritional and exercise interventions will be needed.

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“…In the particular case of visceral adiposity, they are associated with an increased risk of cardiovascular and metabolic morbidity and mortality [ 51 ]. The biological mechanisms linked to the excess of visceral fat, among which low-grade chronic inflammation, oxidative stress, and altered adipokine pattern, also favor the development of other pathological conditions such as osteoarticular [ 52 ], respiratory [ 53 ], dermatological [ 54 ] diseases, or some types of cancer [ 55 ]. Furthermore, people with overweight or obesity frequently show sleep [ 56 ] and psychological disturbances [ 57 ] which in turn could worsen the outcome of obesity.…”

Section: Introductionmentioning

confidence: 99%

Application of Artificial Neural Networks (ANN) to Elucidate the Connections among Smell, Obesity with Related Metabolic Alterations, and Eating Habit in Patients with Weight Excess

Velluzzi

Deledda

Lombardo³

et al. 2023

Metabolites

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Obesity is a severe health problem linked to an increased risk of comorbidity and mortality and its etiopathogenesis includes genetic, epigenetic, microbiota composition, and environmental factors, such as dietary habits. The olfactory system plays an important role in controlling food intake and meal size, influencing body weight and energy balance. This study aims to identify the connection between olfactory function and clinical and nutritional aspects related to weight excess in a group of 68 patients with overweight or obesity. All participants underwent the evaluation of olfactory function, anthropometric data (weight, height, BMI, waist circumference), clinical data (hypertension, disglycemia, dyslipidemia, metabolic syndrome), and adherence to the Mediterranean diet (Mediterranean Diet Score). A fourth-generation artificial neural network data mining approach was used to uncover trends and subtle associations between variables. Olfactory tests showed that 65% of patients presented hyposmia. A negative correlation was found between olfactory scores and systolic blood pressure, fasting plasma glucose, and triglycerides levels, but a positive correlation was found between olfactory scores and the Mediterranean diet score. The methodology of artificial neural networks and the semantic connectivity map “Auto-Contractive Map” highlighted the underlying scheme of the connections between the variables considered. In particular, hyposmia was linked to obesity and related metabolic alterations and the male sex. The female sex was connected with normosmia, higher adherence to the Mediterranean diet, and normal values of blood pressure, lipids, and glucose levels. These results highlight an inverse correlation between olfactory skills and BMI and show that a normosmic condition, probably because of greater adherence to the Mediterranean diet, seems to protect not only from an excessive increase in body weight but also from associated pathological conditions such as hypertension and metabolic syndrome.

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Mediterranean Diet, Lifestyle and Quality of Life in Sardinian Patients Affected with Hidradenitis Suppurativa

Cited by 14 publications

References 60 publications

Diet and physical activity as risk‐reducing factors for hidradenitis suppurativa

Diet and physical activity as risk‐reducing factors for hidradenitis suppurativa

Effect of a Low-Moderate Exercise Program on Dysmetabolism in Older Adults: Results of a Randomized Controlled Trial

Application of Artificial Neural Networks (ANN) to Elucidate the Connections among Smell, Obesity with Related Metabolic Alterations, and Eating Habit in Patients with Weight Excess

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