2015
DOI: 10.1016/j.jtos.2014.12.002
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Meibomian Glands and Ocular Surface Inflammation

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Cited by 85 publications
(95 citation statements)
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References 88 publications
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“…This finding suggests that MGD is associated with cardiovascular diseases, which was demonstrated earlier in a tertiary hospital of Taiwan 13. Furthermore, MGD has been regarded as the primary cause of blepharitis over the past decades,23 suggesting that a significant correlation may exist between cardiovascular diseases and blepharitis. In the current study, blepharitis was associated with several cardiovascular diseases, including hyperlipidaemia and coronary artery diseases.…”
Section: Discussionsupporting
confidence: 61%
“…This finding suggests that MGD is associated with cardiovascular diseases, which was demonstrated earlier in a tertiary hospital of Taiwan 13. Furthermore, MGD has been regarded as the primary cause of blepharitis over the past decades,23 suggesting that a significant correlation may exist between cardiovascular diseases and blepharitis. In the current study, blepharitis was associated with several cardiovascular diseases, including hyperlipidaemia and coronary artery diseases.…”
Section: Discussionsupporting
confidence: 61%
“…Therefore, dysfunction of the meibomian glands (MGD) leads to an impairment of ocular surface lubrication and wetness (dry eye syndrome) as well as induction of local inflammatory responses in the ocular surface. In turn, Suzuki et al (2015) proposed a concept of one unit, i.e., the “meibomian gland and ocular surface” by encountering patients with meibomitis (an inflammatory form of MGD) of which successful management is essential to the treatment of inflammation in the ocular surface.…”
Section: Introductionmentioning
confidence: 99%
“…Más esetekben a kötőhártya epithel sejtekben az intercelluláris adhéziós molekula-1 (ICAM-1) és a HLA-DR gyulladásos markerek emelkedett szintjeit mérték. Egy tanulmány során oculáris rosaceás betegek bőréből vett biopsziás mintákban a veleszületett immunitásban résztvevő interleukin-1β, interleukin-1, őssejtfaktor, monocyta kemoattraktáns protein-1 (MCP-1) és α-interferon emelkedett szinteket mértek, bizonyítva szerepüket a betegségben (13,14). Mikroorganizmusok, mint a Helicobacter pylori, Demodex folliculorum, Demodex brevis és Staphylococcus epidermidis is felmerülnek okozati tényezőként, de szerepük vitatott (13,15 …”
Section: Etiológia éS Patofiziológiaunclassified
“…Fontos lenne egy pontos diagnosztikai teszt kidolgozása, azonban a mai napig nem találtak megfelelő szerológiai vagy szövettani markert. Potenciális teszt lehet a glikánok vizsgálata, ugyanis csökkent N-glikán szintet mértek rosaceás betegek esetén könnyben és nyálban (13,14).…”
Section: áBraunclassified
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