Meiotic inheritance of a fungal supernumerary chromosome and its effect on sexual fertility in Nectria haematococca

Garmaroodi, H. Sadeghi; Taga, Masatoki

doi:10.1016/j.funbio.2015.07.004

Cited by 6 publications

(2 citation statements)

References 46 publications

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“…However, in contrast, to the meiotic drive in Z. tritici the supernumerary chromosome 14 in N. haematococca appears to be preferentially inherited from the male parent. In a more recent study unpaired chr14 of N. haematococca showed Mendelian segregation during meiosis (Garmaroodi and Taga, 2015), and therefore the linkage of female fertility and supernumerary chromosome inheritance is still mechanistically unclear. The example from N. haematococca however underlines that inheritance of supernumerary chromosomes can be influenced by the sexual roles of the parental strains.…”

Section: Discussionmentioning

confidence: 99%

Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus

Habig

Kema

Stukenbrock

2018

eLife

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Meiosis is a key cellular process of sexual reproduction that includes pairing of homologous sequences. In many species however, meiosis can also involve the segregation of supernumerary chromosomes, which can lack a homolog. How these unpaired chromosomes undergo meiosis is largely unknown. In this study we investigated chromosome segregation during meiosis in the haploid fungus Zymoseptoria tritici that possesses a large complement of supernumerary chromosomes. We used isogenic whole chromosome deletion strains to compare meiotic transmission of chromosomes when paired and unpaired. Unpaired chromosomes inherited from the male parent as well as paired supernumerary chromosomes in general showed Mendelian inheritance. In contrast, unpaired chromosomes inherited from the female parent showed non-Mendelian inheritance but were amplified and transmitted to all meiotic products. We concluded that the supernumerary chromosomes of Z. tritici show a meiotic drive and propose an additional feedback mechanism during meiosis, which initiates amplification of unpaired female-inherited chromosomes.

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Section: Discussionmentioning

confidence: 99%

Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus

Habig

Kema

Stukenbrock

2018

eLife

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“…The accessory chromosome of the rice blast fungus M. oryzae (called mini-chromosomes in this species) also shows non-Mendelian transmission during crosses due to nondisjunction during meiosis I or meiosis II (Orbach et al 1996 ). Loss and corresponding disomy of the accessory chromosome PDA1-CDC in N. haematococca MPVI (called conditionally dispensable chromosome in this species) suggest the occurrence of nondisjunction of chromosomes in meiosis I (Miao et al 1991 ; Garmaroodi and Taga 2007 , 2015 ). Accessory chromosomes in Z. tritici also show non-Mendelian inheritance with up to 20% of the progeny from a meiotic cross being reported to have lost one or more accessory chromosomes (Fouché et al 2018 ; Wittenberg et al 2009 ).…”

Section: Non-mendelian Segregation and Meiotic Drives Of Accessory Ch...mentioning

confidence: 96%

Non-Mendelian transmission of accessory chromosomes in fungi

2022

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Non-Mendelian transmission has been reported for various genetic elements, ranging from small transposons to entire chromosomes. One prime example of such a transmission pattern are B chromosomes in plants and animals. Accessory chromosomes in fungi are similar to B chromosomes in showing presence/absence polymorphism and being non-essential. How these chromosomes are transmitted during meiosis is however poorly understood—despite their often high impact on the fitness of the host. For several fungal organisms, a non-Mendelian transmission or a mechanistically unique meiotic drive of accessory chromosomes have been reported. In this review, we provide an overview of the possible mechanisms that can cause the non-Mendelian transmission or meiotic drives of fungal accessory chromosomes. We compare processes responsible for the non-Mendelian transmission of accessory chromosomes for different fungal eukaryotes and discuss the structural traits of fungal accessory chromosomes affecting their meiotic transmission. We conclude that research on fungal accessory chromosomes, due to their small size, ease of sequencing, and epigenetic profiling, can complement the study of B chromosomes in deciphering factors that influence and regulate the non-Mendelian transmission of entire chromosomes.

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2 Origin, Function, and Transmission of Accessory Chromosomes

Habig

Stukenbrock

2020

Genetics and Biotechnology

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Meiotic inheritance of a fungal supernumerary chromosome and its effect on sexual fertility in Nectria haematococca

Cited by 6 publications

References 46 publications

Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus

Meiotic drive of female-inherited supernumerary chromosomes in a pathogenic fungus

Non-Mendelian transmission of accessory chromosomes in fungi

2 Origin, Function, and Transmission of Accessory Chromosomes

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