Melanoma Epidemiology and Prevention

Murali, Sowmiya; Logue, Mary E.; Talamantes, Yvonne; Berwick, Marianne

doi:10.1007/978-3-319-78310-9_3

Cited by 3 publications

(1 citation statement)

References 263 publications

(265 reference statements)

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“…It has been estimated that an extra 10 percent decrease in ozone levels could lead to an additional 4,500 cases of melanoma and 300,000 cases of nonmelanoma skin cancers. Melanoma is a serious type of skin malignancies that continue to promote throughout the world especially within the white population of the United States from 1975 to 2013 (Murali et al, 2018). Furthermore, according to the National Cancer Institute reports, more than 91,000 new cases of melanoma cancer were accounted for in the United States in 2018 and more than one million Americans are living with melanoma cancer.Skin cancer is divided into two main types: nonmelanoma (keratinocyte cancer) and melanoma skin cancer.…”

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confidence: 99%

Strategies in DNA vaccine for melanoma cancer

Rezaei

Davoudian

Khalili

et al. 2020

Pigment Cell Melanoma Res

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Cancer is considered as one of the leading causes of human death worldwide. According to the National Centre for Health Statistics (NCHS), over 600,000 people have died of cancer just in the United States in 2019. Moreover, the NCHS reported that there will be approximately more than 90,000 new cases of melanoma in situ of the skin in 2020 (Siegel et al., 2019). However, the World Health Organization (WHO) has predicted that these statistics may be changed by coronavirus disease 2019 (COVID-19) outbreak in 2020.According to the WHO, 2 to 3 million cases of nonmelanoma skin cancer and more than 132,000 cases of melanomas are diagnosed annually. It has been estimated that an extra 10 percent decrease in ozone levels could lead to an additional 4,500 cases of melanoma and 300,000 cases of nonmelanoma skin cancers. Melanoma is a serious type of skin malignancies that continue to promote throughout the world especially within the white population of the United States from 1975 to 2013 (Murali et al., 2018). Furthermore, according to the National Cancer Institute reports, more than 91,000 new cases of melanoma cancer were accounted for in the United States in 2018 and more than one million Americans are living with melanoma cancer.Skin cancer is divided into two main types: nonmelanoma (keratinocyte cancer) and melanoma skin cancer. The keratinocyte cancer results from skin cells named keratinocytes and rarely spreads to other parts of the body. Keratinocyte cancer has two main subtypes including squamous cell carcinoma (SCC) and basal cell carcinoma (BCC). SCC is most common in those areas of the body that are frequently exposed to the sunlight; it also develops in the areas that do not receive sun exposure such as genitals, lips, and the mouth. BCC

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mentioning

confidence: 99%

Strategies in DNA vaccine for melanoma cancer

Rezaei

Davoudian

Khalili

et al. 2020

Pigment Cell Melanoma Res

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Effects of pesticides on human physiology, genetics, and evolution

Karwal

Mittal

Nagar

et al. 2022

Emerging Contaminants in the Environment

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Primary Hepatic Melanoma: A Diagnostic Surprise

Krishan,

Pandey,

Sakhuja

et al. 2024

Int J Surg Pathol

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Melanoma is a relatively rare malignancy with a highly aggressive biological behavior. Metastases to other sites, like lymph nodes and liver are common, but primary hepatic melanoma is a rarity with poor survival ranging from months to few years. Diagnosis of primary hepatic melanoma via clinical features and imaging technology is difficult because of its ambiguous features. Here, we present a 26-year-old North Indian woman admitted in the department of gastrointestinal surgery at our tertiary care hospital with the complaint of pain in the abdomen for a month associated with the loss of appetite and subsequent weight loss. The liver function tests were within normal limits and viral markers were negative. The triple-phase computed tomography scan of abdomen showed significant hepatomegaly and two well-defined lesions in both lobes of the liver. Histopathological evaluation was performed on the core liver biopsies submitted from the liver lesions. A malignant tumor with abundant black intracytoplasmic pigment was identified. Immunohistochemistry proved the tumor to be melanoma. The detailed clinical history, laboratory, and radiological investigations were acquired and analyzed to rule out a metastatic lesion of the same. A final diagnosis of primary hepatic melanoma was thus rendered. Primary hepatic melanoma is extremely uncommon and has been rarely reported. Preoperative diagnosis is challenging due to low index of suspicion and nonspecific clinical features. In this case report, we discuss the clinicopathological features of primary hepatic melanoma and review the literature so as to increase the awareness and improve our understanding of the disease.

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Melanoma Epidemiology and Prevention

Cited by 3 publications

References 263 publications

Strategies in DNA vaccine for melanoma cancer

Strategies in DNA vaccine for melanoma cancer

Effects of pesticides on human physiology, genetics, and evolution

Primary Hepatic Melanoma: A Diagnostic Surprise

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