Melanosis of the areola in dermoscopy

Blum, Andreas; Metzler, Gisela; Caroli, Ulrich M.

doi:10.1016/j.jaad.2004.04.011

Cited by 17 publications

(34 citation statements)

References 7 publications

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“…Only a few cases of melanoses of the areola are reported in the literature [1,2,3]. Blum et al [3] described the dermoscopic findings in a case of melanosis of the areola.…”

Section: Discussionmentioning

confidence: 99%

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Diagnostic Pitfall: Pigmented Lesion of the Nipple – Correlation between Dermoscopy, Reflectance Confocal Microscopy and Histopathology

Kolm¹,

Kamarashev²,

Kerl³

et al. 2010

Dermatology

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We present an unusual case of a nevus of the nipple changing during pregnancy which caused a diagnostic pitfall. Nevi on the nipple and areola are infrequent, and diagnostic criteria for clinical, dermoscopy or reflectance confocal microscopy examination for nevi in this ‘special location’ are still missing. We comment on the literature on dermoscopic findings in mammary lesions and their management during pregnancy, as well as the challenging histopathology of nevi along the milk line. Finally, we focus on two main limitations of reflectance confocal microscopy: the misinterpretation of dendritic cells and the limitation of the imaging depth.

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“…Only a few cases of melanoses of the areola are reported in the literature [1,2,3]. Blum et al [3] described the dermoscopic findings in a case of melanosis of the areola.…”

Section: Discussionmentioning

confidence: 99%

“…Blum et al [3] described the dermoscopic findings in a case of melanosis of the areola. They found that the hyperpigmentation was arranged in a cobblestone pattern due to the anatomy of the normal skin of the areola.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Pitfall: Pigmented Lesion of the Nipple – Correlation between Dermoscopy, Reflectance Confocal Microscopy and Histopathology

Kolm¹,

Kamarashev²,

Kerl³

et al. 2010

Dermatology

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“…The differential diagnosis of pigmented lesions of the nipple includes melanocytic nevus, nevoid hyperkeratosis of the nipple, reactive hyperkeratosis, melanosis of the areola, melanoma and pigmented Paget’s disease [1,2,3,4,8]. Dermoscopy and RCM have been described only in few of these conditions.…”

Section: Discussionmentioning

confidence: 99%

“…Dermoscopy and RCM have been described only in few of these conditions. Melanosis of the areola and nipple is characterized on dermoscopy by a cobblestone pattern combined with hyperpigmentation [2]. Pigmented Paget’s disease shows on dermoscopy a non-specific pattern with a pigmented area that is characterized by light brown diffuse pigmentation with irregular black dots and small grey-blue structures and a whitish-pink area that shows irregular linear vessels resembling an area of regression [3].…”

Section: Discussionmentioning

confidence: 99%

“…In some cases, the differential diagnosis between melanocytic nevus, nevoid hyperkeratosis of the nipple, reactive hyperkeratosis, melanosis of the areola, melanoma and pigmented Paget’s disease on clinical grounds alone is difficult [1,2,3,4]. Dermoscopy and in vivo reflectance confocal microscopy (RCM) may improve diagnostic accuracy, but to date only few case reports concerning dermoscopy and RCM features of these entities occurring on the nipple have been reported [5].…”

Section: Introductionmentioning

confidence: 99%

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Dermoscopy and in vivo Reflectance Confocal Microscopy of a Congenital Nevus of the Nipple

et al. 2010

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We report a 26-year-old male with a 4 mm diameter, asymmetric, irregularly pigmented and bordered, brown maculopapular lesion on the right nipple present since childhood with enlargement of the lesion within the last 3 months. Dermoscopy revealed a global globular pattern with the presence of focally light brown globules and irregular black globules in its centre. In vivo reflectance confocal microscopy (RCM) revealed dense junctional and dermal melanocytic nests of different sizes and shapes that appeared as sharply demarcated round to oval reflective structures; cellular outlines of single melanocytes were not always detected. In the centre of the lesion within the upper dermis, irregularly shaped, homogeneously reflecting structures were observed. As a clear differentiation between clusters of melanophages and melanocytic nests could not be made with certainty, an excisional biopsy was performed to establish the diagnosis of compound nevus with features of congenital nevus. Therefore, to prove that dermoscopic globules correlated with melanophages, the correlation between dermoscopic RCM and histopathology was necessary.

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