Melasma in Men: A Hormonal Profile

Sialy, R; Hassan, Iffat; Kaur, Inderjeet; Dash, R. J.

doi:10.1111/j.1346-8138.2000.tb02122.x

Cited by 47 publications

(33 citation statements)

References 4 publications

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“…74 Furthermore, increased levels of LH and reduced levels of testosterone were identified in 15 men with melasma in India. 75 In France, it was reported the case of a man with complete hypogonadism - which increases LH and FSH levels, and reduces testosterone levels - who developed facial melasma. 76 …”

Section: Etiology Physiopathology and Risk Factorsmentioning

confidence: 99%

Melasma: a clinical and epidemiological review

Handel¹,

Miot

2014

An. Bras. Dermatol.

298

320

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Melasma is a chronic acquired hypermelanosis of the skin, characterized by irregular brown macules symmetrically distributed on sun-exposed areas of the body, particularly on the face. It is a common cause of demand for dermatological care that affects mainly women (especially during the menacme), and more pigmented phenotypes (Fitzpatrick skin types III-V). Due to its frequent facial involvement, the disease has an impact on the quality of life of patients. Its pathogeny is not yet completely understood, although there are some known triggering factors such as sun exposure, pregnancy, sexual hormones, inflammatory processes of the skin, use of cosmetics, steroids, and photosensitizing drugs. There is also a clear genetic predisposition, since over 40% of patients reported having relatives affected with the disease. In this manuscript, the authors discuss the main clinical and epidemiological aspects of melasma.

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Section: Etiology Physiopathology and Risk Factorsmentioning

confidence: 99%

Melasma: a clinical and epidemiological review

Handel¹,

Miot

2014

An. Bras. Dermatol.

298

320

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“…[8] Other etiological factors that have been described in men with melasma include the use of vegetable oil especially mustard oil on the face[57] and diethylstilboestrol therapy for prostate cancer. [8]…”

Section: Epidemiologymentioning

confidence: 99%

Melasma update

Arora

Garg

Sonthalia

et al. 2014

Indian Dermatol Online J

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Melasma is an acquired pigmentary disorder characterized by symmetrical hyperpigmented macules on the face. Its pathogenesis is complex and involves the interplay of various factors such as genetic predisposition, ultraviolet radiation, hormonal factors, and drugs. An insight into the pathogenesis is important to devise treatment modalities that accurately target the disease process and prevent relapses. Hydroquinone remains the gold standard of treatment though many newer drugs, especially plant extracts, have been developed in the last few years. In this article, we review the pathogenetic factors involved in melasma. We also describe the newer treatment options available and their efficacy. We carried out a PubMed search using the following terms “melasma, pathogenesis, etiology, diagnosis, treatment” and have included data of the last few years.

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“…On the other hand, previous studies have suggested that the main associated factors of melasma in men are: UV irradiation, genetic influences, and subtle testicular resistance. [2][3][4]9 Knowledge of the morphologic and histopathological characteristics of melasma in men is essential to understand its pathogenesis. The aim of the current study was to investigate the histopathological differences between male melasma skin and the adjacent control skin, and to compare the histopathological characteristics of male melasma skin with those of female melasma and nonmelasma skin with solar lentigo.…”

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confidence: 99%