Melorheostosis of the sacrum causing acute-onset neurological symptoms

Yoon, Joongchul; Shafai, Laila Al; Nahal, Ayoub; Turcotte, Robert; Martin, Marie-Hélène

doi:10.1007/s00256-011-1216-1

Cited by 7 publications

(5 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…7 8 Cases with myelopathic symptoms secondary to the spinal cord or nerve root compression by hyperostotic bone in melorheostosis have been reported. 9 10 11 12 13 14 …”

Section: Discussionmentioning

confidence: 99%

Spinal Melorheostosis Associated with Intradural Fibrous Band and Extensive Lipomatosis Causing Thoracic Cord Tethering and Myelomalacia: A Unique Case Highlighting Importance of MRI in Management

Dhanokar

Thippeswamy

Shetty

et al. 2022

Indian J Radiol Imaging

View full text Add to dashboard Cite

Axial melorheostosis is rare with only few cases reported and even fewer with symptoms. While symptoms secondary to neural foramen or spinal canal stenosis caused by hyperostotic bone are common, only three symptomatic cases of spinal melorheostosis with associated intradural lipomatous lesions have been reported to date. In none of them the fibrous component of lipofibromatous lesion was identified preoperatively on magnetic resonance imaging. We report here a case of 18-year-old male who presented with thoracic myelopathy secondary to widespread spinal melorheostosis associated with extensive intradural lipomatosis and fibrous component in thoracic lipoma, causing tethering of thoracic spinal cord and myelomalacia. The patient was treated with T2 to T9 posterior instrumented stabilization followed by T3 to T8 laminectomy along with selective thoracic lipofibromatous tumor debulking. Detection of the fibromatous component in multilevel extensive intradural lipomatosis associated with melorheostosis is helpful in planning selection of the level of surgical excision and decompression.

show abstract

“…7 8 Cases with myelopathic symptoms secondary to the spinal cord or nerve root compression by hyperostotic bone in melorheostosis have been reported. 9 10 11 12 13 14 …”

Section: Discussionmentioning

confidence: 99%

Spinal Melorheostosis Associated with Intradural Fibrous Band and Extensive Lipomatosis Causing Thoracic Cord Tethering and Myelomalacia: A Unique Case Highlighting Importance of MRI in Management

Dhanokar

Thippeswamy

Shetty

et al. 2022

Indian J Radiol Imaging

View full text Add to dashboard Cite

show abstract

“…. An open method is preferred for biopsy rather than a percutaneous approach 20) . Although the radiographic and bone scintigraphic appearances of melorheostosis have been well described, CT and MRI help confirm and accurately localize zones of hyperostosis in the spine and provide means of assessing degrees of spinal canal and foraminal narrowing 8) .…”

Section: Discussionmentioning

confidence: 99%

“…Common causes of the condition include soft disc herniation, neural foraminal stenosis by an osteophyte, ossification of the posterior longitudinal ligament, or traumatic fracture, but rare conditions like neoplasia also need to be considered 4,19) . Melorheostosis is a rare connective tissue disease that causes overgrowth of cortical bone 16,20) . The condition is also called as Léri disease after it was first described by Léri and Joanny 9) in 1922.…”

Section: Introductionmentioning

confidence: 99%

Cervical Radiculopathy from Spinal Melorheostosis: A Case Report and a Review of the Literature

Kim

Ryu

Shinn

et al. 2020

Nerve

View full text Add to dashboard Cite

Cervical radiculopathy is caused by mechanical compression and subsequent inflammation of a cervical nerve root and is usually caused by soft disc herniation. Melorheostosis is a rare connective tissue disease causing overgrowth of cortical bone. We describe a rare presentation of melorheostosis and its successful surgical treatment. A 59-year-old woman with persistent neck pain and radiating pain to the left arm of duration 3 months visited our out-patient clinic. On neurologic examination, the patient showed left C7 dermatome hypoesthesia. Her symptoms did not respond to medication or physical therapy, and thus, biopsy and surgery were performed under suspicion of melorheostosis. Persistent pain was relieved and the histologic examination was consistent with melorheostosis. Spine melorheostosis is rare but symptoms such as pain are responsive to surgery.

show abstract

“…Review of literature reveals symptomatic cases may present with scoliosis, stiffness, back pain, progressive myelopathy, radiculopathy, giddiness, and symptoms of vertebrobasilar insufficiency. [5678910] Soft tissue abnormalities consisting of osseous, chondroid, vascular, and fibrocartilaginous tissue have been reported in 76% of cases of melorheostosis. Vascular and lymphatic malformations associated with melorheostosis have been enlisted in Table 1.…”

Section: Discussionmentioning

confidence: 99%

Melorheostosis: Two atypical cases

Sureka

Mittal

Udhaya

et al. 2014

Indian Journal of Radiology and Imaging

View full text Add to dashboard Cite

Melorheostosis is an uncommon mesenchymal dysplasia that rarely affects the axial skeleton. We describe two atypical cases of melorheostosis with classical imaging findings – the first one involving the cervico-dorsal spine with encroachment of left vertebral artery canal causing attenuation of the left vertebral artery and the second one of mixed sclerosing bony dysplasia (monomelic involvement coexisting with osteopoikilosis).

show abstract

Melorheostosis of the sacrum causing acute-onset neurological symptoms

Cited by 7 publications

References 11 publications

Spinal Melorheostosis Associated with Intradural Fibrous Band and Extensive Lipomatosis Causing Thoracic Cord Tethering and Myelomalacia: A Unique Case Highlighting Importance of MRI in Management

Spinal Melorheostosis Associated with Intradural Fibrous Band and Extensive Lipomatosis Causing Thoracic Cord Tethering and Myelomalacia: A Unique Case Highlighting Importance of MRI in Management

Cervical Radiculopathy from Spinal Melorheostosis: A Case Report and a Review of the Literature

Melorheostosis: Two atypical cases

Contact Info

Product

Resources

About