Melt-Electrospun Fibers for Advances in Biomedical Engineering, Clean Energy, Filtration, and Separation

Góra, Aleksander; Sahay, Rahul; Thavasi, Velmurugan; Ramakrishna, Seeram

doi:10.1080/15583724.2011.594196

Cited by 70 publications

(31 citation statements)

References 48 publications

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“…As an eco‐friendly microfiber/nanofiber spinning method, melt electrospinning has recently attracted scientific attention and broadened the scope for direct 3D writing of biopolymers for a range of scaffold designs in tissue engineering …”

Section: Introductionmentioning

confidence: 99%

The effects of processing parameters on the morphology of PLA/PEG melt electrospun fibers

Nazari

Garmabi

2017

Polymer International

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Electrospinning of a polymer melt is an ideal technique to produce highly porous nanofibrous or microfibrous scaffolds appropriate for biomedical applications. In recent decades, melt electrospinning has been known as an eco‐friendly procedure as it eliminates the cytotoxic effects of the solvents used in solution electrospinning. In this work, the effects of spinning conditions such as temperature, applied voltage, nozzle to collector distance and collector type as well as polyethylene glycol (PEG) concentration on the diameter of melt electrospun polylactic acid (PLA)/PEG fibers were studied. The thermal stability of PLA/PEG blends was monitored through TGA and rheometry. Morphological investigations were carried out via optical and scanning electron microscopy. Based on the results, blends were almost stable over the temperature range of melt electrospinning (170 − 230 °C) and a short spinning time of 5 min. To obtain non‐woven meshes with uniform fiber morphologies, experimental parameters were optimized using ANOVA. While increasing the temperature, applied voltage and PEG content resulted in thinner fibers, PEG concentration was the most influential factor on the fiber diameter. In addition, a nozzle to collector distance of 10 cm was found to be the most suitable for preparing uniform non‐woven PLA/PEG meshes. At higher PEG concentrations, alterations in the collector distance did not affect the uniformity of fibers, although at lower distances vigorous bending instabilities due to polarity augmentation and viscosity reduction resulted in curly fibrous meshes. Finally, the finest and submicron scale fibers were obtained through melt electrospinning of PLA/PEG (70/30) blend collected on a metallic frame. © 2017 Society of Chemical Industry

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Section: Introductionmentioning

confidence: 99%

The effects of processing parameters on the morphology of PLA/PEG melt electrospun fibers

Nazari

Garmabi

2017

Polymer International

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“…Due to the nanoscale diameter range of electrospun fibers, electrospun nanofibrous webs have high surface area and highly porous structure, in addition, design flexibility and easy encapsulation of active agents is a great advantage of electrospun nanofibers. Although melt electrospinning is possible (Góra, Sahay, Thavasi, & Ramakrishna, 2011), solution electrospinning is mostly employed for producing nanofibers in which polymers are being dissolved and electrospun from their concentrated solutions (Uyar & Kny, 2017;Wendorff et al, 2012). Since most of the polymers are synthetic-based and the majority of the polymers are dissolved in organic solvents having environmental hazards, the electrospinning process which involves the use of organic solvents somewhat limits the application of such electrospun materials in healthcare, pharmaceuticals, food and food packaging.…”

Section: Introductionmentioning

confidence: 99%

Electrospinning of cyclodextrin/linalool-inclusion complex nanofibers: Fast-dissolving nanofibrous web with prolonged release and antibacterial activity

et al. 2017

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a b s t r a c tThe volatility and limited water solubility of linalool is a critical issue to be solved. Here, we demonstrated the electrospinning of polymer-free nanofibrous webs of cyclodextrin/linalool-inclusion complex (CD/linalool-IC-NFs). Three types of modified cyclodextrin (HPbCD, MbCD, and HPcCD) were used to electrospin CD/linalool-IC-NFs. Free-standing CD/linalool-IC-NFs facilitate maximum loading of linalool up to 12% (w/w). A significant amount of linalool (45-89%) was preserved in CD/linalool-IC-NFs, due to enhancement in the thermal stability of linalool by cyclodextrin inclusion complexation. Remarkably, CD/linalool-IC-NFs have shown fast-dissolving characteristics in which these nanofibrous webs dissolved in water within two seconds. Furthermore, linalool release from CD/linalool-IC-NFs inhibited growth of model Gram-negative (E. coli) and Gram-positive (S. aureus) bacteria to a great extent. Briefly, characteristics of liquid linalool have been preserved in a solid nanofiber form and designed CD/linalool-IC-NFs confer high loading capacity, enhanced shelf life and strong antibacterial activity of linalool.

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“…The possibilities for the reduction in the fibre diameter with the additives could be: (i) the reduction in the melt viscosity and/ or (ii) increase in the electrical conductivity [21,22]. Therefore, the shear viscosity and the electrical conductivity of the polymer melt with the additives were evaluated.…”

Section: Resultsmentioning

confidence: 99%

Melt-electrospinning of polypropylene with conductive additives

et al. 2012

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In this paper, the feasibility of fabricating polypropylene (PP) nanofibres was investigated using conductive additives such as sodium oleate (SO) and sodium chloride (NaCl) during melt-electrospinning. PP of high melt flow index (MFI = 2000) was used with varying amounts of additives. The effects of amount of additives on the fibre diameter and morphology were investigated. The lowest fibre diameters of 0.371 ± 0.106 and 0.310 ± 0.102 lm were achieved with 7 % SO and 5 % NaCl, respectively. The fabrication of nanofibres was attributed to the increase in the electrical conductivity with the introduction of the additives. The increase in the electrical conductivity was greater in the case of NaCl, due to the smaller ionic size of NaCl. Differential scanning calorimetry results showed complex melting behaviour during the heating cycles for the fibres containing SO; and double melting peaks during the second heating cycle for the fibres containing NaCl. X-ray diffraction studies showed the fibres fabricated with the additives contained lower degrees of crystallinity compared to the as-spun fibre and the crystallinity was increased after annealing. The fibres fabricated with the additives contained a-form crystals only which did not change after annealing. The fibres fabricated from pure polymer and with the additives were hydrophobic in nature. The hydrophobicity was marginally decreased with the addition of SO and NaCl.

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Melt-Electrospun Fibers for Advances in Biomedical Engineering, Clean Energy, Filtration, and Separation

Cited by 70 publications

References 48 publications

The effects of processing parameters on the morphology of PLA/PEG melt electrospun fibers

The effects of processing parameters on the morphology of PLA/PEG melt electrospun fibers

Electrospinning of cyclodextrin/linalool-inclusion complex nanofibers: Fast-dissolving nanofibrous web with prolonged release and antibacterial activity

Melt-electrospinning of polypropylene with conductive additives

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