Melt spinning and hydrolysis of poly(glycolic acid).

Biodegradation in vivo of modified and unmodified PG (polyglycolide) and PGL (copolymer glycolide — L — lactide) monofilament sutures were studied using 1H‐ NMR, wide and small angle X‐ray scattering, differential scanning calorimetry (DSC), electron microscopy (EM), Fourier transform (FT) Raman spectroscopy methods. It was found that the process includes a steady‐state and accelerated stages of biodegradation. The suture biostability depends on polymer morphology changing widely over the suture draw ratio. The modification of polymer chain results in an increase in suture useful lifetime without significant changes of complete polymer degradation time. It was also established the important role of weak intermolecular hydrogen bonds such as CH–‐O=C in the suture stability.

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Kinetics and mechanism of biodegradation of (co)polyglycolide sutures

Belen'kaya

Sakharova

Sinevich

et al. 1999

Macromolecular Symposia

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Preparation of block copoly(ester-ether) comprising poly(l-lactide) and poly(oxypropylene) and degradation of its fibre in vitro and in vivo

Kimura

Matsuzaki

Yamane

et al. 1989

Polymer

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Absorbable Suture Materials: Preparation and Properties

Singhal

Singh

Ray

1988

Journal of Macromolecular Science, Part C: Polymer Reviews

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Melt spinning and hydrolysis of poly(glycolic acid).

Cited by 3 publications

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Kinetics and mechanism of biodegradation of (co)polyglycolide sutures

Kinetics and mechanism of biodegradation of (co)polyglycolide sutures

Preparation of block copoly(ester-ether) comprising poly(l-lactide) and poly(oxypropylene) and degradation of its fibre in vitro and in vivo

Absorbable Suture Materials: Preparation and Properties

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