Membranas de látex natural na herniorrafia diafragmática experimental em cães

Zimmermann, M.; Raiser, Alceu Gaspar; Braga, Felipe Vieira; Trindade, Ana Luiza; Lopes, Sonia T.A.

doi:10.1590/s0102-09352008000600026

Cited by 8 publications

(3 citation statements)

References 14 publications

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“…Furthermore, NRL has been used in several biomedical applications due to its angiogenesis potential and biocompatibility, such as bone regeneration [33][34][35], chronic and diabetic ulcers healing [36,37], repair of tympanum [38] and of diaphragmatic defects in dogs [39], and construction of medical prostheses and grafts [29].…”

Section: Introductionmentioning

confidence: 99%

Silver nanoparticles effect on drug release of metronidazole in natural rubber latex dressing

et al. 2021

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Natural rubber latex (NRL) from Hevea brasiliensis has shown great potential for dermal applications due to its angiogenesis capacity and biocompatibility. Metronidazole (MET) is a synthetic antibiotic used to treat various infections. However, this drug reports dangerous effects when high concentrations are administered. In this study, we used silver nanoparticles (AgNPs) in order to minimize these toxicological effects. For this, the membranes were characterized by physicochemical, molecular modeling, in vitro release and hemocompatibility assays. In the release assays, 14.25% of the MET and 27.28% of the AgNP + MET complex were released simultaneously, indicating that these nanoparticles work as drug carriers. Molecular modeling simulation helped to explain the in vitro release results, showing that AgNPs can interact more efficiently with MET molecules. Moreover, similarities in reactivity between NRL and MET suggested that some drug molecules may remain in the matrix during the release process. The membranes did not present significant hemolytic activity after 24 h of incubation. These results demonstrated that the NRL + AgNP + MET membrane can be used as a dressing in the treatment of infectious processes.

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Section: Introductionmentioning

confidence: 99%

Silver nanoparticles effect on drug release of metronidazole in natural rubber latex dressing

et al. 2021

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“…Após a segunda semana da ruptura, o tecido diafragmático sofre formações de aderências com elevado nível de tecido fibrovascular organizado (Zimmermann et al, 2008), impossibilitando a aproximação das bordas durante a herniorrafia simples, com aumento da tensão na linha de sutura e inevitável predisposição à deiscência dos planos de sutura, dificultando a cicatrização por primeira intenção. Nestes casos, são necessários procedimentos cirúrgicos mais apropriados, como a utilização de enxertos (Mazzanti et al, 2001) o que coincide com o observado no animal atendido.…”

Section: Discussionunclassified

Histerocele diafragmática en una gata gestante: Reporte de un caso

Cavalcanti¹,

Yamaguchi²,

Silva³

et al. 2017

Pubvet

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RESUMO.Descreve-se um caso de atendimento a animal, felino, adulto, fêmea, com diagnóstico de hérnia diafragmática crônica tendo o útero gravídico em fase final de gestação como parte do conteúdo herniário. O gradativo crescimento fetal no decorrer da gestação determinou importante comprometimento respiratório. A gravidade do quadro exigiu interrupção cirúrgica da gestação com posterior herniorrafia por flape peritoneal, porém não houve êxito e o animal veio a óbito ao final do procedimento cirúrgico. O óbito foi atribuído à cronicidade e gravidade da condição clínica em que se encontrava. Este relato ressalta a importância da correção imediata de hérnias diafragmáticas e do acompanhamento pré-natal durante a gestação. Palavras chave: Dispneia, interrupção gestacional, trauma torácicoDiaphragmatic hernia containing pregnant uterus as content in feline: Case report ABSTRACT. A case of animal care, feline, adult, female is described, with diagnosis of chronic diaphragmatic hernia with the gravid uterus in the final stage of gestation as part of the hernial content. Gradual fetal growth during pregnancy led to significant respiratory impairment. The severity of the condition necessitated a surgical interruption of gestation with posterior herniorrhaphy with peritoneal flap, but it did not succeed and the animal died at the end of the surgical procedure. The death was attributed to the chronicity and severity of the clinical condition in which it was found. This report highlights the importance of immediate correction of diaphragmatic hernias and prenatal follow-up during pregnancy. Keyword: Dyspnea, gestational interruption, thoracic traumaHisterocele diafragmática en una gata gestante: Reporte de un caso RESUMEN. Se describe el reporte de un caso de una felina adulta, en fase final de gestación con diagnóstico de hernia diafragmática crónica conteniendo útero con fetos. El progresivo crecimiento fetal durante el transcurso de la gestación determinó una importante complicación respiratoria. La gravedad del cuadro requirió de la interrupción quirúrgica de la gestación con posterior herniorrafia por flape peritoneal, pero no hubo éxito y el animal murió al final del procedimiento quirúrgico. El fallecimiento fue atribuido a la cronicidad y gravedad de la condición clínica en que se encontraba. Este reporte resalta la importancia de la corrección inmediata de hernias diafragmáticas y del acompañamiento prenatal durante la gestación.

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“…Access to this structure can be performed by median laparotomy, sternotomy, lateral intercostal thoracotomy, or the association of these techniques (BESALTI et al, 2011;OZER et al, 2007). Extensive diaphragmatic defects can be corrected with the use of biological or synthetic implants (ZIMMERMANN et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Clinical, surgical, and radiographic aspects in a white‑eared opossum (Didelphis albiventris) with traumatic diaphragmatic hernia

Souza

Piccoli

Quintana

et al. 2021

AVB

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This is the case of a specimen of Didelphis albiventris with signs of respiratory difficulty after a dog attack. Thoracic radiographic examination revealed pneumothorax, pulmonary contusion, and rib fracture, but no alteration compatible with diaphragmatic hernia was observed. Pneumothorax was reduced and the other alterations were treated. However, clinical manifestations persisted, and thus a contrast-gastrointestinal radiographic study was performed, showing abdominal organs in the thoracic cavity and loss of diaphragmatic line. The surgical approach was instituted, with access to the diaphragm through median laparotomy. Through the diaphragmatic rupture, present in the left antimere, there were herniated liver and gastric portions, intestinal segments, and omentum. After inspection and repositioning of the abdominal organs, the diaphragm raffia was performed with single sutures interrupted with 3-0 Nylon thread. The patient’s complete recovery occurred 14 days after the surgical procedure, with remission of clinical manifestations and normality of thoracic images in radiographic studies.

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Membranas de látex natural na herniorrafia diafragmática experimental em cães

Cited by 8 publications

References 14 publications

Silver nanoparticles effect on drug release of metronidazole in natural rubber latex dressing

Silver nanoparticles effect on drug release of metronidazole in natural rubber latex dressing

Histerocele diafragmática en una gata gestante: Reporte de un caso

Clinical, surgical, and radiographic aspects in a white‑eared opossum (Didelphis albiventris) with traumatic diaphragmatic hernia

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