Membrane Resting and Action Potentials of Single Cardiac Muscle Fibers

Abstract

An initial report is made on the electrocardiogram of a single heart muscle cell in vivo. The On the basis of experience gained in a series of preliminary experiments, the tip of the microelectrode was assumed to lie in the interior of a relatively undamaged fiber when the record obtainecl showed the following characteristics:(1) a series of monophasic action potentials showing (2) overshoot and (3) no appreciable change of shape or form during the series; (4) a resting, potential of more than 50 millix olts;and (5)

Prolonged Action Potentials From Single Nodes of Ranvier

“…The applied solutions contained no sodium. The action potentials recorded by Katz and Fatt were similar to those obtained from heart muscle by intracellular recording (Draper and Weidmann, 1951;Woodbury et al, 1950;Trautwein and Zink, 1952). Tasaki (1953) reported a prolongation of single fiber action potential in heroine and sinomenine.…”

The membrane resting and action potentials of the cat auricle

“…Measurements of membrane and action potentials in single fibres of cardiac tissue have been reported by Woodbury, Woodbury & Hecht (1950) and Woodbury, Hecht & Christopherson (1951) for the frog ventricle; and by Coraboeuf & Weidmann (1949a, b), Draper & Weidmann (1951) and Weidmann (1951) for conducting tissue of the mammalian ventricle. As yet no reports have appeared on the nature of auricular muscle fibre potentials.…”

A Simplified Sucrose-Gap Method for Recording from Bullfrog Cardiac Muscle

“…This method is similar to that described by Koketsu and Nishi (1968) for recording from sympathetic ganglion cells. It will be shown that the membrane potential 1 Fig.1). B: Schematic drawing of the bridge circuit used for hyperpolarization or depolarization of the membrane by DC current through the E1 and E2 electrodes.…”